Combinatorial Effects of Double Cardiomyopathy Mutant Alleles in Rodent Myocytes: A Predictive Cellular Model of Myofilament Dysregulation in Disease

por Davis, Jennifer, Metzger, Joseph M.
Publicado 2010

Ex Vivo Stretch Reveals Altered Mechanical Properties of Isolated Dystrophin-Deficient Hearts

por Barnabei, Matthew S., Metzger, Joseph M.
Publicado 2012

Inexpensive, serotype-independent protocol for native and bioengineered recombinant adeno-associated virus purification

por Arden, Erik, Metzger, Joseph M.
Publicado 2016

Cardiac myocyte intrinsic contractility and calcium handling deficits underlie heart organ dysfunction in murine cancer cachexia

por Law, Michelle L., Metzger, Joseph M.
Publicado 2021

Thin Filament Protein Dynamics in Fully Differentiated Adult Cardiac Myocytes: Toward A Model of Sarcomere Maintenance

por Michele, Daniel E., Albayya, Faris P., Metzger, Joseph M.
Publicado 1999

Direct, Differential Effects of Tamoxifen, 4-Hydroxytamoxifen, and Raloxifene on Cardiac Myocyte Contractility and Calcium Handling

por Asp, Michelle L., Martindale, Joshua J., Metzger, Joseph M.
Publicado 2013

Prominent Heart Organ-Level Performance Deficits in a Genetic Model of Targeted Severe and Progressive SERCA2 Deficiency

por Heinis, Frazer I., Andersson, Kristin B., Christensen, Geir, Metzger, Joseph M.
Publicado 2013

Molecular inotropy mediated by cardiac miR-based PDE4D/PRKAR1α/phosphoprotein signaling

por Bedada, Fikru B., Martindale, Joshua J., Arden, Erik, Metzger, Joseph M.
Publicado 2016

Muscle membrane integrity in Duchenne muscular dystrophy: recent advances in copolymer-based muscle membrane stabilizers

por Houang, Evelyne M., Sham, Yuk Y., Bates, Frank S., Metzger, Joseph M.
Publicado 2018

Microtubule-Mediated Misregulation of Junctophilin-2 Underlies T-Tubule Disruptions and Calcium Mishandling in mdx Mice

por Prins, Kurt W., Asp, Michelle L., Zhang, Huiliang, Wang, Wang, Metzger, Joseph M.
Publicado 2016

Colchicine Depolymerizes Microtubules, Increases Junctophilin‐2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension

por Prins, Kurt W., Tian, Lian, Wu, Danchen, Thenappan, Thenappan, Metzger, Joseph M., Archer, Stephen L.
Publicado 2017

Dysregulation of Calcium Handling in Duchenne Muscular Dystrophy-Associated Dilated Cardiomyopathy: Mechanisms and Experimental Therapeutic Strategies

por Law, Michelle L., Cohen, Houda, Martin, Ashley A., Angulski, Addeli Bez Batti, Metzger, Joseph M.
Publicado 2020

Early Detection of Myocardial Bioenergetic Deficits: A 9.4 Tesla Complete Non Invasive (31)P MR Spectroscopy Study in Mice with Muscular Dystrophy

por Cui, Weina, Jang, Albert, Zhang, Pengyuan, Thompson, Brian, Townsend, DeWayne, Metzger, Joseph M., Zhang, Jianyi
Publicado 2015

Investigation of human iPSC-derived cardiac myocyte functional maturation by single cell traction force microscopy

por Wheelwright, Matthew, Win, Zaw, Mikkila, Jennifer L., Amen, Kamilah Y., Alford, Patrick W., Metzger, Joseph M.
Publicado 2018

Investigations of an inducible intact dystrophin gene excision system in cardiac and skeletal muscle in vivo

por Bez Batti Angulski, Addeli, Bauer, John, Cohen, Houda, Kobuke, Kazuhiro, Campbell, Kevin P., Metzger, Joseph M.
Publicado 2020

Sarcomere dynamics revealed by a myofilament integrated FRET-based biosensor in live skeletal muscle fibers

por Martin, Ashley A., Thompson, Brian R., Davis, Jonathan P., Vang, Hluechy, Hahn, Dongwoo, Metzger, Joseph M.
Publicado 2022

Rapid restitution of contractile dysfunction by synthetic copolymers in dystrophin-deficient single live skeletal muscle fibers

por Hahn, Dongwoo, Quick, Joseph D., Thompson, Brian R., Crabtree, Adelyn, Hackel, Benjamin J., Bates, Frank S., Metzger, Joseph M.
Publicado 2023

Duchenne muscular dystrophy: disease mechanism and therapeutic strategies

por Bez Batti Angulski, Addeli, Hosny, Nora, Cohen, Houda, Martin, Ashley A., Hahn, Dongwoo, Bauer, Jack, Metzger, Joseph M.
Publicado 2023

Cardiac Muscle Membrane Stabilization in Myocardial Reperfusion Injury

por Houang, Evelyne M., Bartos, Jason, Hackel, Benjamin J., Lodge, Timothy P., Yannopoulos, Demetris, Bates, Frank S., Metzger, Joseph M.
Publicado 2019

Membrane-stabilizing copolymers confer marked protection to dystrophic skeletal muscle in vivo

por Houang, Evelyne M, Haman, Karen J, Filareto, Antonio, Perlingeiro, Rita C, Bates, Frank S, Lowe, Dawn A, Metzger, Joseph M
Publicado 2015