P1036: REAL-WORLD EFFICACY AND SAFETY OF MIDOSTAURIN-TREATMENT IN PATIENTS WITH ADVANCED SYSTEMIC MASTOCYTOSIS

por Lübke, Johannes, Naumann, Nicole, Metzgeroth, Georgia, Fabarius, Alice, Brand, Timo, Horny, Hans-Peter, Sotlar, Karl, Hofmann, Wolf-Karsten, Schwaab, Juliana, Reiter, Andreas
Publicado 2023

An increased bone mineral density is an adverse prognostic factor in patients with systemic mastocytosis

por Riffel, Philipp, Schwaab, Juliana, Lutz, Christopher, Naumann, Nicole, Metzgeroth, Georgia, Fabarius, Alice, Schoenberg, Stefan O., Hofmann, Wolf-Karsten, Valent, Peter, Reiter, Andreas, Jawhar, Mohamad
Publicado 2020

Myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions: reevaluation of the defining characteristics in a registry-based cohort

por Metzgeroth, Georgia, Steiner, Laurenz, Naumann, Nicole, Lübke, Johannes, Kreil, Sebastian, Fabarius, Alice, Haferlach, Claudia, Haferlach, Torsten, Hofmann, Wolf-Karsten, Cross, Nicholas C. P., Schwaab, Juliana, Reiter, Andreas
Publicado 2023

Response and resistance to cladribine in patients with advanced systemic mastocytosis: a registry-based analysis

por Lübke, Johannes, Naumann, Nicole, Metzgeroth, Georgia, Kreil, Sebastian, Brand, Timo, Horny, Hans-Peter, Sotlar, Karl, Cross, Nicholas C. P., Fabarius, Alice, Valent, Peter, Hofmann, Wolf-Karsten, Reiter, Andreas, Schwaab, Juliana
Publicado 2023

Inhibitory effects of midostaurin and avapritinib on myeloid progenitors derived from patients with KIT D816V positive advanced systemic mastocytosis

por Lübke, Johannes, Naumann, Nicole, Kluger, Sebastian, Schwaab, Juliana, Metzgeroth, Georgia, Evans, Erica, Gardino, Alexandra K., Lengauer, Christoph, Hofmann, Wolf-Karsten, Fabarius, Alice, Cross, Nicholas C. P., Reiter, Andreas, Jawhar, Mohamad
Publicado 2019

The clinical and molecular diversity of mast cell leukemia with or without associated hematologic neoplasm

por Jawhar, Mohamad, Schwaab, Juliana, Meggendorfer, Manja, Naumann, Nicole, Horny, Hans-Peter, Sotlar, Karl, Haferlach, Torsten, Schmitt, Karla, Fabarius, Alice, Valent, Peter, Hofmann, Wolf-Karsten, Cross, Nicholas C.P., Metzgeroth, Georgia, Reiter, Andreas
Publicado 2017

Functional imaging with dual-energy computed tomography for supplementary non-invasive assessment of mast cell burden in systemic mastocytosis

por Riffel, Julia, Lübke, Johannes, Naumann, Nicole, Kreil, Sebastian, Metzgeroth, Georgia, Fabarius, Alice, Sotlar, Karl, Horny, Hans-Peter, Jawhar, Mohamad, Overhoff, Daniel, Schoenberg, Stefan, Hofmann, Wolf-Karsten, Henzler, Thomas, Schwaab, Juliana, Reiter, Andreas, Riffel, Philipp
Publicado 2022

Cytogenetically cryptic ZMYM2-FLT3 and DIAPH1-PDGFRB gene fusions in myeloid neoplasms with eosinophilia

por Jawhar, Mohamad, Naumann, Nicole, Knut, Marcin, Score, Joannah, Ghazzawi, Muna, Schneider, Brigitte, Kreuzer, Karl-Anton, Hallek, Michael, Drexler, Hans G, Chacko, Joseph, Wallis, Louise, Fabarius, Alice, Metzgeroth, Georgia, Hofmann, Wolf-Karsten, Chase, Andrew, Tapper, Will, Reiter, Andreas, Cross, Nicholas C.P.
Publicado 2017

Bone marrow derived stromal cells from myelodysplastic syndromes are altered but not clonally mutated in vivo

por Jann, Johann-Christoph, Mossner, Maximilian, Riabov, Vladimir, Altrock, Eva, Schmitt, Nanni, Flach, Johanna, Xu, Qingyu, Nowak, Verena, Obländer, Julia, Palme, Iris, Weimer, Nadine, Streuer, Alexander, Jawhar, Ahmed, Darwich, Ali, Jawhar, Mohammad, Metzgeroth, Georgia, Nolte, Florian, Hofmann, Wolf-Karsten, Nowak, Daniel
Publicado 2021

Replication stress signaling is a therapeutic target in myelodysplastic syndromes with splicing factor mutations

por Flach, Johanna, Jann, Johann-Christoph, Knaflic, Antje, Riabov, Vladimir, Streuer, Alexander, Altrock, Eva, Xu, Qingyu, Schmitt, Nanni, Obländer, Julia, Nowak, Verena, Danner, Justine, Mehralivand, Arwin, Hofmann, Franziska, Palme, Iris, Jawhar, Ahmed, Wuchter, Patrick, Metzgeroth, Georgia, Nolte, Florian, Hofmann, Wolf-Karsten, Nowak, Daniel
Publicado 2020

Significant improvement of bone marrow-derived MSC expansion from MDS patients by defined xeno-free medium

por Altrock, Eva, Sens-Albert, Carla, Hofmann, Franziska, Riabov, Vladimir, Schmitt, Nanni, Xu, Qingyu, Jann, Johann-Christoph, Rapp, Felicitas, Steiner, Laurenz, Streuer, Alexander, Nowak, Verena, Obländer, Julia, Weimer, Nadine, Palme, Iris, Göl, Melda, Darwich, Ali, Wuchter, Patrick, Metzgeroth, Georgia, Jawhar, Mohamad, Hofmann, Wolf-Karsten, Nowak, Daniel
Publicado 2023

Adverse Prognostic Impact of the KIT D816V Transcriptional Activity in Advanced Systemic Mastocytosis

por Naumann, Nicole, Lübke, Johannes, Baumann, Sofie, Schwaab, Juliana, Hoffmann, Oliver, Kreil, Sebastian, Dangelo, Vito, Reiter, Lukas, Bugert, Peter, Kristensen, Thomas, Sotlar, Karl, Haselmann, Verena, Schneider, Sven, Metzgeroth, Georgia, Weiss, Christel, Popp, Henning D., Fabarius, Alice, Hofmann, Wolf-Karsten, Cross, Nicholas C. P., Reiter, Andreas, Jawhar, Mohamad
Publicado 2021

ICON: Eosinophil Disorders

por Valent, Peter, Klion, Amy D, Rosenwasser, Lanny J, Arock, Michel, Bochner, Bruce S, Butterfield, Joseph H, Gotlib, Jason, Haferlach, Torsten, Hellmann, Andrzej, Horny, Hans-Peter, Leiferman, Kristin M, Metzgeroth, Georgia, Matsumoto, Kenji, Reiter, Andreas, Roufosse, Florence, Rothenberg, Marc E, Simon, Hans-Uwe, Sotlar, Karl, Vandenberghe, Peter, Weller, Peter F, Gleich, Gerald J
Publicado 2012

Proposed refined diagnostic criteria and classification of eosinophil disorders and related syndromes

por Valent, Peter, Klion, Amy D., Roufosse, Florence, Simon, Dagmar, Metzgeroth, Georgia, Leiferman, Kristin M., Schwaab, Juliana, Butterfield, Joseph H., Sperr, Wolfgang R., Sotlar, Karl, Vandenberghe, Peter, Hoermann, Gregor, Haferlach, Torsten, Moriggl, Richard, George, Tracy I., Akin, Cem, Bochner, Bruce S., Gotlib, Jason, Reiter, Andreas, Horny, Hans‐Peter, Arock, Michel, Simon, Hans‐Uwe, Gleich, Gerald J.
Publicado 2022

Genome-wide DNA methylation analysis pre- and post-lenalidomide treatment in patients with myelodysplastic syndrome with isolated deletion (5q)

por Hecht, Anna, Meyer, Julia A., Jann, Johann-Christoph, Sockel, Katja, Giagounidis, Aristoteles, Götze, Katharina S., Letsch, Anne, Haase, Detlef, Schlenk, Richard F., Haferlach, Torsten, Schafhausen, Philippe, Bug, Gesine, Lübbert, Michael, Thol, Felicitas, Büsche, Guntram, Schuler, Esther, Nowak, Verena, Obländer, Julia, Fey, Stephanie, Müller, Nadine, Metzgeroth, Georgia, Hofmann, Wolf-Karsten, Germing, Ulrich, Nolte, Florian, Reinwald, Mark, Nowak, Daniel
Publicado 2021

Preclinical evaluation of eltrombopag in a PDX model of myelodysplastic syndromes

por Schmitt, Nanni, Jann, Johann-Christoph, Altrock, Eva, Flach, Johanna, Danner, Justine, Uhlig, Stefanie, Streuer, Alexander, Knaflic, Antje, Riabov, Vladimir, Xu, Qingyu, Mehralivand, Arwin, Palme, Iris, Nowak, Verena, Obländer, Julia, Weimer, Nadine, Haselmann, Verena, Jawhar, Ahmed, Darwich, Ali, Weis, Cleo-Aron, Marx, Alexander, Steiner, Laurenz, Jawhar, Mohamad, Metzgeroth, Georgia, Boch, Tobias, Nolte, Florian, Hofmann, Wolf-Karsten, Nowak, Daniel
Publicado 2021

KIT D816 mutated/CBF-negative acute myeloid leukemia: a poor-risk subtype associated with systemic mastocytosis

por Jawhar, Mohamad, Döhner, Konstanze, Kreil, Sebastian, Schwaab, Juliana, Shoumariyeh, Khalid, Meggendorfer, Manja, Span, Lambert L. F., Fuhrmann, Stephan, Naumann, Nicole, Horny, Hans-Peter, Sotlar, Karl, Kubuschok, Boris, von Bubnoff, Nikolas, Spiekermann, Karsten, Heuser, Michael, Metzgeroth, Georgia, Fabarius, Alice, Klein, Stefan, Hofmann, Wolf-Karsten, Kluin-Nelemans, Hanneke C., Haferlach, Torsten, Döhner, Hartmut, Cross, Nicholas C. P., Sperr, Wolfgang R., Valent, Peter, Reiter, Andreas
Publicado 2019

MARS: Mutation-Adjusted Risk Score for Advanced Systemic Mastocytosis

por Jawhar, Mohamad, Schwaab, Juliana, Álvarez-Twose, Iván, Shoumariyeh, Khalid, Naumann, Nicole, Lübke, Johannes, Perkins, Cecelia, Muñoz-González, Javier I., Meggendorfer, Manja, Kennedy, Vanessa, Metzgeroth, Georgia, Fabarius, Alice, Pfeifer, Dietmar, Sotlar, Karl, Horny, Hans-Peter, von Bubnoff, Nikolas, Haferlach, Torsten, Cross, Nicholas C.P., Hofmann, Wolf-Karsten, Sperr, Wolfgang R., García-Montero, Andrés C., Valent, Peter, Gotlib, Jason, Orfao, Alberto, Reiter, Andreas
Publicado 2019

Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation

por Heil, Joschka, Olsavszky, Victor, Busch, Katrin, Klapproth, Kay, de la Torre, Carolina, Sticht, Carsten, Sandorski, Kajetan, Hoffmann, Johannes, Schönhaber, Hiltrud, Zierow, Johanna, Winkler, Manuel, Schmid, Christian David, Staniczek, Theresa, Daniels, Deborah E., Frayne, Jan, Metzgeroth, Georgia, Nowak, Daniel, Schneider, Sven, Neumaier, Michael, Weyer, Vanessa, Groden, Christoph, Gröne, Hermann-Josef, Richter, Karsten, Mogler, Carolin, Taketo, Makoto Mark, Schledzewski, Kai, Géraud, Cyrill, Goerdt, Sergij, Koch, Philipp-Sebastian
Publicado 2021

Inhibition of lysyl oxidases synergizes with 5-azacytidine to restore erythropoiesis in myelodysplastic and myeloid malignancies

por Xu, Qingyu, Streuer, Alexander, Jann, Johann-Christoph, Altrock, Eva, Schmitt, Nanni, Flach, Johanna, Sens-Albert, Carla, Rapp, Felicitas, Wolf, Julia, Nowak, Verena, Weimer, Nadine, Obländer, Julia, Palme, Iris, Kuzina, Mariia, Jawhar, Ahmed, Darwich, Ali, Weis, Cleo-Aron, Marx, Alexander, Wuchter, Patrick, Costina, Victor, Jäger, Evelyn, Sperk, Elena, Neumaier, Michael, Fabarius, Alice, Metzgeroth, Georgia, Nolte, Florian, Steiner, Laurenz, Levkin, Pavel A., Jawhar, Mohamad, Hofmann, Wolf-Karsten, Riabov, Vladimir, Nowak, Daniel
Publicado 2023