Experimental demonstration of tethered gene drive systems for confined population modification or suppression

por Metzloff, Matthew, Yang, Emily, Dhole, Sumit, Clark, Andrew G., Messer, Philipp W., Champer, Jackson
Publicado 2022

A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles

por Yang, Emily, Metzloff, Matthew, Langmüller, Anna M, Xu, Xuejiao, Clark, Andrew G, Messer, Philipp W, Champer, Jackson
Publicado 2022

Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations

por Langmüller, Anna M, Champer, Jackson, Lapinska, Sandra, Xie, Lin, Metzloff, Matthew, Champer, Samuel E, Liu, Jingxian, Xu, Yineng, Du, Jie, Clark, Andrew G, Messer, Philipp W
Publicado 2022