DNA Methylation in Osteoarthritis

por den Hollander, Wouter, Meulenbelt, Ingrid
Publicado 2015

Genotype-Based Score Test for Association Testing in Families

por Uh, Hae-Won, Beekman, Marian, Meulenbelt, Ingrid, Houwing-Duistermaat, Jeanine J.
Publicado 2015

Genetic Contribution to the Development of Radiographic Knee Osteoarthritis in a Population Presenting with Nonacute Knee Symptoms a Decade Earlier

por Huétink, Kasper, van der Voort, Paul, Bloem, Johan L., Nelissen, Rob G. H. H., Meulenbelt, Ingrid
Publicado 2016

A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis

por Katsoula, Georgia, Steinberg, Julia, Tuerlings, Margo, Coutinho de Almeida, Rodrigo, Southam, Lorraine, Swift, Diane, Meulenbelt, Ingrid, Wilkinson, J Mark, Zeggini, Eleftheria
Publicado 2022

Hyper-physiologic mechanical cues, as an osteoarthritis disease relevant environmental perturbation, cause a critical shift in set-points of methylation at transcriptionally active...

por Bloks, Niek GC, Dicks, Amanda, Harissa, Zainab, Nelissen, Rob GHH, Hajmousa, Ghazaleh, Ramos, Yolande FM, Almeida, Rodrigo Coutinho, Guilak, Farshid, Meulenbelt, Ingrid
Publicado 2023

Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility—Towards Identification of Applicable Early OA Biomarkers

por Ramos, Yolande F. M., Coutinho de Almeida, Rodrigo, Lakenberg, Nico, Suchiman, Eka, Mei, Hailiang, Kloppenburg, Margreet, Nelissen, Rob G. H. H., Meulenbelt, Ingrid
Publicado 2021

Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis

por Coutinho de Almeida, Rodrigo, Tuerlings, Margo, Ramos, Yolande, Den Hollander, Wouter, Suchiman, Eka, Lakenberg, Nico, Nelissen, Rob G H H, Mei, Hailiang, Meulenbelt, Ingrid
Publicado 2022

GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis-associated factors

por Leijten, Jeroen CH, Bos, Steffan D, Landman, Ellie BM, Georgi, Nicole, Jahr, Holger, Meulenbelt, Ingrid, Post, Janine N, van Blitterswijk, Clemens A, Karperien, Marcel
Publicado 2013

An epigenome-wide view of osteoarthritis in primary tissues

por Kreitmaier, Peter, Suderman, Matthew, Southam, Lorraine, Coutinho de Almeida, Rodrigo, Hatzikotoulas, Konstantinos, Meulenbelt, Ingrid, Steinberg, Julia, Relton, Caroline L., Wilkinson, J. Mark, Zeggini, Eleftheria
Publicado 2022

The role of TNFRSF11B in development of osteoarthritic cartilage

por Rodríguez Ruiz, Alejandro, Tuerlings, Margo, Das, Ankita, Coutinho de Almeida, Rodrigo, Suchiman, H Eka D, Nelissen, Rob G H H, Ramos, Yolande F M, Meulenbelt, Ingrid
Publicado 2021

Vitamin K antagonist anticoagulant usage is associated with increased incidence and progression of osteoarthritis

por Boer, Cindy G, Szilagyi, Ingrid, Nguyen, N Long, Neogi, Tuhina, Meulenbelt, Ingrid, Ikram, M Arfan, Uitterlinden, André G, Bierma-Zeinstra, Sita, Stricker, Bruno H, van Meurs, Joyce B
Publicado 2021

Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis

por Houtman, Evelyn, van Hoolwerff, Marcella, Lakenberg, Nico, Suchiman, Eka H. D., van der Linden-van der Zwaag, Enrike, Nelissen, Rob G. H. H., Ramos, Yolande F. M., Meulenbelt, Ingrid
Publicado 2021

Characterizing the secretome of licensed hiPSC-derived MSCs

por Ramos, Yolande F. M., Tertel, Tobias, Shaw, Georgina, Staubach, Simon, de Almeida, Rodrigo Coutinho, Suchiman, Eka, Kuipers, Thomas B., Mei, Hailiang, Barry, Frank, Murphy, Mary, Giebel, Bernd, Meulenbelt, Ingrid
Publicado 2022

Aberrant Calreticulin Expression in Articular Cartilage of Dio2 Deficient Mice

por Bomer, Nils, Cornelis, Frederique M. F., Ramos, Yolande F. M., den Hollander, Wouter, Lakenberg, Nico, van der Breggen, Ruud, Storms, Lies, Slagboom, P. Eline, Lories, Rik J. U., Meulenbelt, Ingrid
Publicado 2016

High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II

por van Hoolwerff, Marcella, Rodríguez Ruiz, Alejandro, Bouma, Marga, Suchiman, H. Eka D., Koning, Roman I., Jost, Carolina R., Mulder, Aat A., Freund, Christian, Guilak, Farshid, Ramos, Yolande F. M., Meulenbelt, Ingrid
Publicado 2021

Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis

por Garcia de Vinuesa, Amaya, Sanchez‐Duffhues, Gonzalo, Blaney‐Davidson, Esmeralda, van Caam, Arjan, Lodder, Kirsten, Ramos, Yolande, Kloppenburg, Margreet, Meulenbelt, Ingrid, van der Kraan, Peter, Goumans, Marie‐José, ten Dijke, Peter
Publicado 2021

Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells

por Rodríguez Ruiz, Alejandro, Dicks, Amanda, Tuerlings, Margo, Schepers, Koen, van Pel, Melissa, Nelissen, Rob G. H. H., Freund, Christian, Mummery, Christine L., Orlova, Valeria, Guilak, Farshid, Meulenbelt, Ingrid, Ramos, Yolande F. M.
Publicado 2021

Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants

por Houtman, Evelyn, Tuerlings, Margo, Riechelman, Janne, Suchiman, Eka H. E. D., van der Wal, Robert J. P., Nelissen, Rob G. H. H., Mei, Hailiang, Ramos, Yolande F. M., Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Publicado 2021

Radiographic endophenotyping in hip osteoarthritis improves the precision of genetic association analysis

por Panoutsopoulou, Kalliope, Thiagarajah, Shankar, Zengini, Eleni, Day-Williams, Aaron G, Ramos, Yolande FM, Meessen, Jennifer MTA, Huetink, Kasper, Nelissen, Rob GHH, Southam, Lorraine, Rayner, N William, Doherty, Michael, Meulenbelt, Ingrid, Zeggini, Eleftheria, Wilkinson, J Mark
Publicado 2017

Elucidating Epigenetic Regulation by Identifying Functional cis‐Acting Long Noncoding RNAs and Their Targets in Osteoarthritic Articular Cartilage

por van Hoolwerff, Marcella, Metselaar, Paula I., Tuerlings, Margo, Suchiman, H. Eka D., Lakenberg, Nico, Ramos, Yolande F.M., Cats, Davy, Nelissen, Rob G.H.H., Broekhuis, Demiën, Mei, Hailiang, de Almeida, Rodrigo Coutinho, Meulenbelt, Ingrid
Publicado 2020