Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment

por Ko, Juyeon, Meyer, April N., Haas, Martin, Donoghue, Daniel J.
Publicado 2021

Transmembrane Domain Sequence Requirements for Activation of the p185(c-neu) Receptor Tyrosine Kinase

por Chen, Lucinda I., Webster, Melanie K., Meyer, April N., Donoghue, Daniel J.
Publicado 1997

Oncogenic driver FGFR3-TACC3 is dependent on membrane trafficking and ERK signaling

por Nelson, Katelyn N., Meyer, April N., Wang, Clark G., Donoghue, Daniel J.
Publicado 2018

Oncogenic fusion protein FGFR2-PPHLN1: Requirements for biological activation, and efficacy of inhibitors

por Li, Fangda, Meyer, April N., Peiris, Malalage N., Nelson, Katelyn N., Donoghue, Daniel J.
Publicado 2020

Proteomic analysis reveals dual requirement for Grb2 and PLCγ1 interactions for BCR-FGFR1-Driven 8p11 cell proliferation

por Peiris, Malalage N., Meyer, April N., Warda, Dalida, Campos, Alexandre Rosa, Donoghue, Daniel J.
Publicado 2022

The Receptor Tyrosine Kinase FGFR4 Negatively Regulates NF-kappaB Signaling

por Drafahl, Kristine A., McAndrew, Christopher W., Meyer, April N., Haas, Martin, Donoghue, Daniel J.
Publicado 2010

Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability

por Wang, Clark G., Peiris, Malalage N., Meyer, April N., Nelson, Katelyn N., Donoghue, Daniel J.
Publicado 2023

Novel Lys63-linked ubiquitination of IKKβ induces STAT3 signaling

por Gallo, Leandro H, Meyer, April N, Motamedchaboki, Khatereh, Nelson, Katelyn N, Haas, Martin, Donoghue, Daniel J
Publicado 2014

Oncogenic fusion protein BCR-FGFR1 requires the breakpoint cluster region-mediated oligomerization and chaperonin Hsp90 for activation

por Peiris, Malalage N., Meyer, April N., Nelson, Katelyn N., Bisom-Rapp, Ezra W., Donoghue, Daniel J.
Publicado 2020

Characterization of iPS87, a prostate cancer stem cell-like cell line

por Assoun, Erika N., Meyer, April N., Jiang, Maggie Y., Baird, Stephen M., Haas, Martin, Donoghue, Daniel J.
Publicado 2020

Fibroblast Growth Factor Receptor 3 Interacts with and Activates TGFβ-Activated Kinase 1 Tyrosine Phosphorylation and NFκB Signaling in Multiple Myeloma and Bladder Cancer

por Salazar, Lisa, Kashiwada, Tamara, Krejci, Pavel, Meyer, April N., Casale, Malcolm, Hallowell, Matthew, Wilcox, William R., Donoghue, Daniel J., Thompson, Leslie Michels
Publicado 2014

Tyrosine Phosphorylation Allows Integration of Multiple Signaling Inputs by IKKβ

por Meyer, April N., Drafahl, Kristine A., McAndrew, Christopher W., Gilda, Jennifer E., Gallo, Leandro H., Haas, Martin, Brill, Laurence M., Donoghue, Daniel J.
Publicado 2013

Oncogenic mutations in IKKβ function through global changes induced by K63-linked ubiquitination and result in autocrine stimulation

por Meyer, April N., Gallo, Leandro H., Ko, Juyeon, Cardenas, Guillermo, Nelson, Katelyn N., Siari, Asma, Campos, Alexandre R., Whisenant, Thomas C., Donoghue, Daniel J.
Publicado 2018

Early Human Prostate Adenocarcinomas Harbor Androgen-Independent Cancer Cells

por Fiñones, Rita R., Yeargin, Jo, Lee, Melissa, Kaur, Aman Preet, Cheng, Clari, Sun, Paulina, Wu, Christopher, Nguyen, Catherine, Wang-Rodriguez, Jessica, Meyer, April N., Baird, Stephen M., Donoghue, Daniel J., Haas, Martin
Publicado 2013