Targeting SHIP1 and SHIP2 in Cancer

por Pedicone, Chiara, Meyer, Shea T., Chisholm, John D., Kerr, William G.
Publicado 2021

N1-Benzyl Tryptamine Pan-SHIP1/2 Inhibitors: Synthesis and Preliminary Biological Evaluation as Anti-Tumor Agents

por Fernandes, Sandra, Meyer, Shea T., Shah, Jigisha P., Adhikari, Arijit A., Kerr, William G., Chisholm, John D.
Publicado 2022

LRBA Deficiency Can Lead to Lethal Colitis That Is Diminished by SHIP1 Agonism

por Sudan, Raki, Fernandes, Sandra, Srivastava, Neetu, Pedicone, Chiara, Meyer, Shea T., Chisholm, John D., Engelman, Robert W., Kerr, William G.
Publicado 2022

Discovery of a novel SHIP1 agonist that promotes degradation of lipid-laden phagocytic cargo by microglia

por Pedicone, Chiara, Fernandes, Sandra, Matera, Alessandro, Meyer, Shea T., Loh, Stewart, Ha, Jeung-Hoi, Bernard, Denzil, Chisholm, John D., Paolicelli, Rosa Chiara, Kerr, William G.
Publicado 2022

Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment

por Fernandes, Sandra, Srivastava, Neetu, Pedicone, Chiara, Sudan, Raki, Luke, Elizabeth A., Dungan, Otto M., Pacherille, Angela, Meyer, Shea T., Dormann, Shawn, Schurmans, Stéphane, Chambers, Benedict J., Chisholm, John D., Kerr, William G.
Publicado 2023