Repurposing approved drugs as potential inhibitors of 3CL-protease of SARS-CoV-2: Virtual screening and structure based drug design

por Meyer-Almes, Franz-Josef
Publicado 2020

Non-Hydroxamate Zinc-Binding Groups as Warheads for Histone Deacetylases

por Frühauf, Anton, Meyer-Almes, Franz-Josef
Publicado 2021

Continuous enzyme activity assay for high-throughput classification of histone deacetylase 8 inhibitors

por Schweipert, Markus, Amurthavasan, Anuja, Meyer-Almes, Franz-Josef
Publicado 2023

Significance of Five-Membered Heterocycles in Human Histone Deacetylase Inhibitors

por Frühauf, Anton, Behringer, Martin, Meyer-Almes, Franz-Josef
Publicado 2023

Methionine 274 Is Not the Determining Factor for Selective Inhibition of Histone Deacetylase 8 (HDAC8) by L-Shaped Inhibitors

por Jänsch, Niklas, Lang, Kim Leoni, Meyer-Almes, Franz-Josef
Publicado 2022

Substrate specificity and function of acetylpolyamine amidohydrolases from Pseudomonas aeruginosa

por Krämer, Andreas, Herzer, Jan, Overhage, Joerg, Meyer-Almes, Franz-Josef
Publicado 2016

The enzyme activity of histone deacetylase 8 is modulated by a redox-switch

por Jänsch, Niklas, Meyners, Christian, Muth, Marius, Kopranovic, Aleksandra, Witt, Olaf, Oehme, Ina, Meyer-Almes, Franz-Josef
Publicado 2018

Synthesis and HDAC inhibitory activity of pyrimidine-based hydroxamic acids

por Jakubkiene, Virginija, Valiulis, Gabrielius Ernis, Schweipert, Markus, Zubriene, Asta, Matulis, Daumantas, Meyer-Almes, Franz-Josef, Tumkevicius, Sigitas
Publicado 2022

Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors

por Baud, Matthias G J, Leiser, Thomas, Petrucci, Vanessa, Gunaratnam, Mekala, Neidle, Stephen, Meyer-Almes, Franz-Josef, Fuchter, Matthew J
Publicado 2013

Switching the Switch: Ligand Induced Disulfide Formation in HDAC8

por Jänsch, Niklas, Sugiarto, Wisely Oki, Muth, Marius, Kopranovic, Aleksandra, Desczyk, Charlotte, Ballweg, Matthias, Kirschhöfer, Frank, Brenner‐Weiss, Gerald, Meyer‐Almes, Franz‐Josef
Publicado 2020

Mechanistic Insights into Binding of Ligands with Thiazolidinedione Warhead to Human Histone Deacetylase 4

por Schweipert, Markus, Jänsch, Niklas, Upadhyay, Neha, Tilekar, Kalpana, Wozny, Ewelina, Basheer, Sidra, Wurster, Eva, Müller, Marlene, C S, Ramaa, Meyer-Almes, Franz-Josef
Publicado 2021

Design, Synthesis, and Biological Evaluation of Novel Quinazolin-4(3H)-One-Based Histone Deacetylase 6 (HDAC6) Inhibitors for Anticancer Activity

por Khetmalis, Yogesh Mahadu, Fathima, Ashna, Schweipert, Markus, Debarnot, Cécile, Bandaru, Naga Venkata Madhusudhan Rao, Murugesan, Sankaranarayanan, Jamma, Trinath, Meyer-Almes, Franz-Josef, Sekhar, Kondapalli Venkata Gowri Chandra
Publicado 2023

3‐Chloro‐5‐Substituted‐1,2,4‐Thiadiazoles (TDZs) as Selective and Efficient Protein Thiol Modifiers

por Jänsch, Niklas, Frühauf, Anton, Schweipert, Markus, Debarnot, Cécile, Erhardt, Miriam, Brenner‐Weiss, Gerald, Kirschhöfer, Frank, Jasionis, Tomas, Čapkauskaitė, Edita, Zubrienė, Asta, Matulis, Daumantas, Meyer‐Almes, Franz‐Josef
Publicado 2022

The Proapoptotic Influenza A Virus Protein PB1-F2 Forms a Nonselective Ion Channel

por Henkel, Michael, Mitzner, David, Henklein, Peter, Meyer-Almes, Franz-Josef, Moroni, Anna, DiFrancesco, Mattia L., Henkes, Leonhard M., Kreim, Michael, Kast, Stefan M., Schubert, Ulrich, Thiel, Gerhard
Publicado 2010

Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription

por Minisini, Martina, Di Giorgio, Eros, Kerschbamer, Emanuela, Dalla, Emiliano, Faggiani, Massimo, Franforte, Elisa, Meyer-Almes, Franz-Josef, Ragno, Rino, Antonini, Lorenzo, Mai, Antonello, Fiorentino, Francesco, Rotili, Dante, Chinellato, Monica, Perin, Stefano, Cendron, Laura, Weichenberger, Christian X, Angelini, Alessandro, Brancolini, Claudio
Publicado 2022