A new “angle” on kinase inhibitor design: Prioritizing amphosteric activity above kinase inhibition

por Meyerowitz, Justin G, Weiss, William A, Gustafson, W Clay
Publicado 2015

Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors

por Burnett, G. Leslie, Yang, Yu C., Aggen, James B., Pitzen, Jennifer, Gliedt, Micah K., Semko, Chris M., Marquez, Abby, Evans, James W., Wang, Gang, Won, Walter S., Tomlinson, Aidan C. A., Kiss, Gert, Tzitzilonis, Christos, Thottumkara, Arun P., Cregg, James, Mellem, Kevin T., Choi, Jong S., Lee, Julie C., Zhao, Yongyuan, Lee, Bianca J., Meyerowitz, Justin G., Knox, John E., Jiang, Jingjing, Wang, Zhican, Wildes, David, Wang, Zhengping, Singh, Mallika, Smith, Jacqueline A. M., Gill, Adrian L.
Publicado 2022

Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19

por Feyaerts, Dorien, Hédou, Julien, Gillard, Joshua, Chen, Han, Tsai, Eileen S., Peterson, Laura S., Ando, Kazuo, Manohar, Monali, Do, Evan, Dhondalay, Gopal K.R., Fitzpatrick, Jessica, Artandi, Maja, Chang, Iris, Snow, Theo T., Chinthrajah, R. Sharon, Warren, Christopher M., Wittman, Rich, Meyerowitz, Justin G., Ganio, Edward A., Stelzer, Ina A., Han, Xiaoyuan, Verdonk, Franck, Gaudillière, Dyani K., Mukherjee, Nilanjan, Tsai, Amy S., Rumer, Kristen K., Jiang, Sizun, Valdés Ferrer, Sergio Iván, Kelly, J. Daniel, Furman, David, Aghaeepour, Nima, Angst, Martin S., Boyd, Scott D., Pinsky, Benjamin A., Nolan, Garry P., Nadeau, Kari C., Gaudillière, Brice, McIlwain, David R.
Publicado 2021

Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19

por Feyaerts, Dorien, Hédou, Julien, Gillard, Joshua, Chen, Han, Tsai, Eileen S., Peterson, Laura S., Ando, Kazuo, Manohar, Monali, Do, Evan, Dhondalay, Gopal K.R., Fitzpatrick, Jessica, Artandi, Maja, Chang, Iris, Snow, Theo T., Chinthrajah, R. Sharon, Warren, Christopher M., Wittman, Richard, Meyerowitz, Justin G., Ganio, Edward A., Stelzer, Ina A., Han, Xiaoyuan, Verdonk, Franck, Gaudillière, Dyani K., Mukherjee, Nilanjan, Tsai, Amy S., Rumer, Kristen K., Jacobsen, Danielle R., Bjornson-Hooper, Zachary B., Jiang, Sizun, Saavedra, Sergio Fragoso, Valdés Ferrer, Sergio Iván, Kelly, J. Daniel, Furman, David, Aghaeepour, Nima, Angst, Martin S., Boyd, Scott D., Pinsky, Benjamin A., Nolan, Garry P., Nadeau, Kari C., Gaudillière, Brice, McIlwain, David R.
Publicado 2022