A recombinantly tailored β-defensin that displays intensive macropinocytosis-mediated uptake exerting potent efficacy against K-Ras mutant pancreatic cancer

por Du, Yue, Shang, Bo-yang, Sheng, Wei-jin, Zhang, Sheng-hua, Li, Yi, Miao, Qing-fang, Zhen, Yong-su
Publicado 2016

Development of a novel multi-functional integrated bioconjugate effectively targeting K-Ras mutant pancreatic cancer

por Wang, Yang-Yang, Li, Liang, Liu, Xiu-Jun, Miao, Qing-Fang, Li, Yi, Zhang, Meng-Ran, Zhen, Yong-Su
Publicado 2022

Excellent effects and possible mechanisms of action of a new antibody–drug conjugate against EGFR-positive triple-negative breast cancer

por Zhou, Dan-Dan, Bai, Wei-Qi, Zhai, Xiao-Tian, Sun, Li-Ping, Zhen, Yong-Su, Li, Zhuo-Rong, Miao, Qing-Fang
Publicado 2021

A bispecific enediyne-energized fusion protein targeting both epidermal growth factor receptor and insulin-like growth factor 1 receptor showing enhanced antitumor efficacy against...

por Guo, Xiao-Fang, Zhu, Xiao-Fei, Cao, Hai-Ying, Zhong, Gen-Shen, Li, Liang, Deng, Bao-Guo, Chen, Ping, Wang, Pei-Zhen, Miao, Qing-Fang, Zhen, Yong-Su
Publicado 2017

An EGFR‐targeting antibody–drug conjugate LR004‐VC‐MMAE: potential in esophageal squamous cell carcinoma and other malignancies

por Hu, Xin‐yue, Wang, Rong, Jin, Jie, Liu, Xiu‐jun, Cui, A‐long, Sun, Lian‐qi, Li, Yan‐ping, Li, Yi, Wang, Yu‐cheng, Zhen, Yong‐su, Miao, Qing‐fang, Li, Zhuo‐rong
Publicado 2018