A CRE/DRE dual recombinase transgenic mouse reveals synaptic zinc–mediated thalamocortical neuromodulation

por Kouvaros, Stylianos, Bizup, Brandon, Solis, Oscar, Kumar, Manoj, Ventriglia, Emilya, Curry, Fallon P., Michaelides, Michael, Tzounopoulos, Thanos
Publicado 2023

Interactions of calmodulin kinase II with the dopamine transporter facilitate cocaine-induced enhancement of evoked dopamine release

por Keighron, Jacqueline D., Bonaventura, Jordi, Li, Yang, Yang, Jae-Won, DeMarco, Emily M., Hersey, Melinda, Cao, Jianjing, Sandtner, Walter, Michaelides, Michael, Sitte, Harald H., Newman, Amy Hauck, Tanda, Gianluigi
Publicado 2023

Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability

por Bonaventura, Jordi, Lam, Sherry, Carlton, Meghan, Boehm, Matthew, Gomez, Juan L., Solís, Oscar, Sánchez-Soto, Marta, Morris, Patrick J., Fredriksson, Ida, Thomas, Craig J., Sibley, David R., Shaham, Yavin, Zarate, Carlos A., Michaelides, Michael
Publicado 2021

Time will tell. Reply to “Comments to pharmacological and behavioral divergence of ketamine enantiomers by Jordi Bonaventura et al.” by Chen et al

por Bonaventura, Jordi, Lam, Sherry, Carlton, Meghan, Boehm, Matthew, Gomez, Juan L., Solís, Oscar, Sánchez-Soto, Marta, Morris, Patrick J., Fredriksson, Ida, Thomas, Craig J., Sibley, David R., Shaham, Yavin, Zarate, Carlos A., Michaelides, Michael
Publicado 2022

A tool for monitoring cell type–specific focused ultrasound neuromodulation and control of chronic epilepsy

por Murphy, Keith R., Farrell, Jordan S., Gomez, Juan L., Stedman, Quintin G., Li, Ningrui, Leung, Steven A., Good, Cameron H., Qiu, Zhihai, Firouzi, Kamyar, Butts Pauly, Kim, Khuri-Yakub, Butrus Pierre T., Michaelides, Michael, Soltesz, Ivan, de Lecea, Luis
Publicado 2022

The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia

por Pappano, William N., Guo, Jun, He, Yupeng, Ferguson, Debra, Jagadeeswaran, Sujatha, Osterling, Donald J., Gao, Wenqing, Spence, Julie K., Pliushchev, Marina, Sweis, Ramzi F., Buchanan, Fritz G., Michaelides, Michael R., Shoemaker, Alexander R., Tse, Chris, Chiang, Gary G.
Publicado 2015

A non-canonical striatopallidal “Go” pathway that supports motor control

por Labouesse, Marie A., Torres-Herraez, Arturo, Chohan, Muhammad O., Villarin, Joseph, Greenwald, Julia, Sun, Xiaoxiao, Zahran, Mysarah, Tang, Alice, Lam, Sherry, Veenstra-VanderWeele, Jeremy, Lacefield, Clay, Bonaventura, Jordi, Michaelides, Michael, Chan, C. Savio, Yizhar, Ofer, Kellendonk, Christoph
Publicado 2023

A non-canonical striatopallidal Go pathway that supports motor control

por Labouesse, Marie A., Torres-Herraez, Arturo, Chohan, Muhammad O., Villarin, Joseph M., Greenwald, Julia, Sun, Xiaoxiao, Zahran, Mysarah, Tang, Alice, Lam, Sherry, Veenstra-VanderWeele, Jeremy, Lacefield, Clay O., Bonaventura, Jordi, Michaelides, Michael, Chan, C. Savio, Yizhar, Ofer, Kellendonk, Christoph
Publicado 2023

Unique pharmacodynamic properties and low abuse liability of the μ-opioid receptor ligand (S)-methadone

por Michaelides, Michael, Levinstein, Marjorie, De Oliveira, Paulo, Casajuana-Martin, Nil, Quiroz, Cesar, Budinich, Reece, Rais, Rana, Rea, William, Ventriglia, Emilya, Llopart, Natàlia, Casadó-Anguera, Verònica, Moreno, Estefanía, Walther, Donna, Glatfelter, Grant, Weinshenker, David, Zarate, Carlos, Casado, Vicent, Baumann, Michael, Pardo, Leonardo, Ferre, Sergi
Publicado 2023

DREADD-mediated amygdala activation is sufficient to induce anxiety-like responses in young nonhuman primates

por Mueller, Sascha A.L., Oler, Jonathan A., Roseboom, Patrick H., Aggarwal, Nakul, Kenwood, Margaux M., Riedel, Marissa K., Elam, Victoria R., Olsen, Miles E., DiFilippo, Alexandra H., Christian, Bradley T., Hu, Xing, Galvan, Adriana, Boehm, Matthew A., Michaelides, Michael, Kalin, Ned H.
Publicado 2023

DREADD-mediated amygdala activation is sufficient to induce anxiety-like responses in young nonhuman primates

por Mueller, Sascha A.L., Oler, Jonathan A., Roseboom, Patrick H., Aggarwal, Nakul, Kenwood, Margaux M., Riedel, Marissa K., Elam, Victoria R., Olsen, Miles E., DiFilippo, Alexandra H., Christian, Bradley T., Hu, Xing, Galvan, Adriana, Boehm, Matthew A., Michaelides, Michael, Kalin, Ned H.
Publicado 2023

Acute engagement of G(q)-mediated signaling in the bed nucleus of the stria terminalis induces anxiety-like behavior

por Mazzone, Christopher M., Pati, Dipanwita, Michaelides, Michael, DiBerto, Jeffrey, Fox, James H., Tipton, Gregory, Anderson, Carlton, Duffy, Kelly, McKlveen, Jessica M., Hardaway, J. Andrew, Magness, Scott T., Falls, William A., Hammack, Sayamwong E., McElligott, Zoe A., Hurd, Yasmin L., Kash, Thomas L.
Publicado 2016

Synaptic Zn(2+) potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior

por Gomez, Juan L., Bonaventura, Jordi, Keighron, Jacqueline, Wright, Kelsey M., Marable, Dondre L., Rodriguez, Lionel A., Lam, Sherry, Carlton, Meghan L., Ellis, Randall J., Jordan, Chloe J., Bi, Guo-hua, Solis, Oscar, Pignatelli, Marco, Bannon, Michael J., Xi, Zheng-Xiong, Tanda, Gianluigi, Michaelides, Michael
Publicado 2021

Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet

por Leggio, Lorenzo, Leko, Andras, Gregory-Flores, Adriana, Marchette, Renata, Gomez, Juan, Vendruscolo, Janaina, Repunte-Canonigo, Vez, Chuong, Vicky, Deschaine, Sara, Whiting, Kimberly, Jackson, Shelley, Cornejo, Maria, Perello, Mario, You, Zhi-Bing, Eckhaus, Michael, Janda, Kim, Zorman, Barry, Sumazin, Pavel, Koob, George, Michaelides, Michael, Sanna, Pietro Paolo, Vendruscolo, Leandro
Publicado 2023

Striatal Rgs4 regulates feeding and susceptibility to diet-induced obesity

por Michaelides, Michael, Miller, Michael L., Egervari, Gabor, Primeaux, Stefany D., Gomez, Juan L., Ellis, Randall J., Landry, Joseph A., Szutorisz, Henrietta, Hoffman, Alexander F., Lupica, Carl R., Loos, Ruth J.F., Thanos, Panayotis K., Bray, George A., Neumaier, John F., Zachariou, Venetia, Wang, Gene-Jack, Volkow, Nora D., Hurd, Yasmin L.
Publicado 2018

Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases

por Michaelides, Michael R., Kluge, Arthur, Patane, Michael, Van Drie, John H., Wang, Ce, Hansen, T. Matthew, Risi, Roberto M., Mantei, Robert, Hertel, Carmen, Karukurichi, Kannan, Nesterov, Alexandre, McElligott, David, de Vries, Peter, Langston, J. William, Cole, Philip A., Marmorstein, Ronen, Liu, Hong, Lasko, Loren, Bromberg, Kenneth D., Lai, Albert, Kesicki, Edward A.
Publicado 2017

Relevance of Spike/Estrogen Receptor-α interaction for endothelial-based coagulopathy induced by SARS-CoV-2

por Barbieri, Silvia Stella, Cattani, Franca, Sandrini, Leonardo, Grillo, Magda Maria, Amendola, Alessandra, Valente, Carmen, Talarico, Carmine, Iaconis, Daniela, Turacchio, Gabriele, Lucariello, Miriam, Lione, Lucia, Salvatori, Erika, Amadio, Patrizia, Garoffolo, Gloria, Maffei, Mariano, Galli, Francesca, Beccari, Andrea Rosario, Sberna, Giuseppe, Marra, Emanuele, Zoppi, Marica, Michaelides, Michael, Roscilli, Giuseppe, Aurisicchio, Luigi, Bertini, Riccardo, Allegretti, Marcello, Pesce, Maurizio
Publicado 2023

Progress towards a public chemogenomic set for protein kinases and a call for contributions

por Drewry, David H., Wells, Carrow I., Andrews, David M., Angell, Richard, Al-Ali, Hassan, Axtman, Alison D., Capuzzi, Stephen J., Elkins, Jonathan M., Ettmayer, Peter, Frederiksen, Mathias, Gileadi, Opher, Gray, Nathanael, Hooper, Alice, Knapp, Stefan, Laufer, Stefan, Luecking, Ulrich, Michaelides, Michael, Müller, Susanne, Muratov, Eugene, Denny, R. Aldrin, Saikatendu, Kumar S., Treiber, Daniel K., Zuercher, William J., Willson, Timothy M.
Publicado 2017

High-potency ligands for DREADD imaging and activation in rodents and monkeys

por Bonaventura, Jordi, Eldridge, Mark A. G., Hu, Feng, Gomez, Juan L., Sanchez-Soto, Marta, Abramyan, Ara M., Lam, Sherry, Boehm, Matthew A., Ruiz, Christina, Farrell, Mitchell R., Moreno, Andrea, Galal Faress, Islam Mustafa, Andersen, Niels, Lin, John Y., Moaddel, Ruin, Morris, Patrick J., Shi, Lei, Sibley, David R., Mahler, Stephen V., Nabavi, Sadegh, Pomper, Martin G., Bonci, Antonello, Horti, Andrew G., Richmond, Barry J., Michaelides, Michael
Publicado 2019

The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification

por Wells, Carrow I., Al-Ali, Hassan, Andrews, David M., Asquith, Christopher R. M., Axtman, Alison D., Dikic, Ivan, Ebner, Daniel, Ettmayer, Peter, Fischer, Christian, Frederiksen, Mathias, Futrell, Robert E., Gray, Nathanael S., Hatch, Stephanie B., Knapp, Stefan, Lücking, Ulrich, Michaelides, Michael, Mills, Caitlin E., Müller, Susanne, Owen, Dafydd, Picado, Alfredo, Saikatendu, Kumar S., Schröder, Martin, Stolz, Alexandra, Tellechea, Mariana, Turunen, Brandon J., Vilar, Santiago, Wang, Jinhua, Zuercher, William J., Willson, Timothy M., Drewry, David H.
Publicado 2021