Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology

por Sutendra, Gopinath, Michelakis, Evangelos D.
Publicado 2013

A Phase-2 NIH-sponsored Randomized Clinical Trial of Rituximab in Scleroderma-associated Pulmonary Arterial Hypertension Did Not Reach Significance for Its Endpoints: End of Story?...

por Zhang, Yongneng, Michelakis, Evangelos D.
Publicado 2021

The time has come to pull renal cancer’s sweet tooth

por Kinnaird, Adam, Michelakis, Evangelos D.
Publicado 2019

Pulmonary Arterial Hypertension

por Michelakis, Evangelos D., Archer, Stephen L.
Publicado 2007

Pioglitazone inhibits HIF-1α-dependent angiogenesis in rats by paracrine and direct effects on endothelial cells

por Dromparis, Peter, Sutendra, Gopinath, Paulin, Roxane, Proctor, Spencer, Michelakis, Evangelos D., McMurtry, M. Sean
Publicado 2014

Reduced native right ventricular T(1 )in Anderson-Fabry disease as compared to patients with pulmonary hypertension

por Pagano, Joseph J, Chow, Kelvin, Khan, Aneal, Michelakis, Evangelos, Paterson, Ian, Oudit, Gavin Y, Thompson, Richard B
Publicado 2014

Reduced Right Ventricular Native Myocardial T(1) in Anderson-Fabry Disease: Comparison to Pulmonary Hypertension and Healthy Controls

por Pagano, Joseph J., Chow, Kelvin, Khan, Aneal, Michelakis, Evangelos, Paterson, Ian, Oudit, Gavin Y., Thompson, Richard B.
Publicado 2016

Exogenous Hydrogen Sulfide (H(2)S) Protects Alveolar Growth in Experimental O(2)-Induced Neonatal Lung Injury

por Vadivel, Arul, Alphonse, Rajesh S., Ionescu, Lavinia, Machado, Desiree S., O’Reilly, Megan, Eaton, Farah, Haromy, Al, Michelakis, Evangelos D., Thébaud, Bernard
Publicado 2014

Effect of Fatty Acids on Human Bone Marrow Mesenchymal Stem Cell Energy Metabolism and Survival

por Fillmore, Natasha, Huqi, Alda, Jaswal, Jagdip S., Mori, Jun, Paulin, Roxane, Haromy, Alois, Onay-Besikci, Arzu, Ionescu, Lavinia, Thébaud, Bernard, Michelakis, Evangelos, Lopaschuk, Gary D.
Publicado 2015

Quantification of pulmonary edema in heart failure using MRI: invasive validation and evaluation in HFpEF and HFrEF patients

por Thompson, Richard B, Chow, Kelvin, Sekowski, Viktor, Michelakis, Evangelos, Pagano, Joseph J, Tymchak, Wayne, Haykowsky, Mark, Ezekowitz, Justin, Oudit, Gavin Y, Dyck, Jason, Paterson, Ian
Publicado 2016

Oral treprostinil improves pulmonary vascular compliance in pulmonary arterial hypertension

por Khan, Akram, White, R. James, Meyer, Gisela, Zamudio, Tomas R. Pulido, Jerjes-Sanchez, Carlos, Johnson, Dana, Grover, Rob, Broderick, Meredith, Ousmanou, Aliou, Holdstock, Louis, Michelakis, Evangelos
Publicado 2022

p53‐Mediated Repression of the PGC1A (PPARG Coactivator 1α) and APLNR (Apelin Receptor) Signaling Pathways Limits Fatty Acid Oxidation Energetics: Implications for Cardio‐oncology...

por Saleme, Bruno, Das, Subhash K., Zhang, Yongneng, Boukouris, Aristeidis E., Lorenzana Carrillo, Maria Areli, Jovel, Juan, Wagg, Cory S., Lopaschuk, Gary D., Michelakis, Evangelos D., Sutendra, Gopinath
Publicado 2020

Updating clinical endpoint definitions

por Hassoun, Paul M., Nikkho, Sylvia, Rosenzweig, Erika B., Moreschi, Gail, Lawrence, John, Teeter, John, Meier, Christian, Ghofrani, Ardeshir H., Minai, Omar, Rinaldi, Paula, Michelakis, Evangelos, Oudiz, Ronald J
Publicado 2013

Right ventricular remodeling and dysfunction among the spectrum of heart failure phenotypes

por Wang, Harris, Xu, Lingyu, Chow, Kelvin, Pagano, Joseph J, Schmidt, Anna, White, James A, Michelakis, Evangelos, Ezekowitz, Justin, Dyck, Jason, Haykowsky, Mark, Oudit, Gavin Y, Thompson, Richard B, Paterson, Ian
Publicado 2016

SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary...

por Zhang, Yongneng, Zervopoulos, Sotirios D., Boukouris, Aristeidis E., Lorenzana‐Carrillo, Maria Areli, Saleme, Bruno, Webster, Linda, Liu, Yongsheng, Haromy, Alois, Tabatabaei Dakhili, Seyed Amirhossein, Ussher, John R., Sutendra, Gopinath, Michelakis, Evangelos D.
Publicado 2021

Quantification of lung water in heart failure using cardiovascular magnetic resonance imaging

por Thompson, Richard B., Chow, Kelvin, Pagano, Joseph J., Sekowski, Viktor, Michelakis, Evangelos D., Tymchak, Wayne, Haykowsky, Mark J., Ezekowitz, Justin A., Oudit, Gavin Y., Dyck, Jason R. B., Kaul, Padma, Savu, Anamaria, Paterson, D. Ian
Publicado 2019

Loss of the fructose transporter SLC2A5 inhibits cancer cell migration

por Groenendyk, Jody, Stoletov, Konstantin, Paskevicius, Tautvydas, Li, Wenjuan, Dai, Ning, Pujol, Myriam, Busaan, Erin, Ng, Hoi Hei, Boukouris, Aristeidis E., Saleme, Bruno, Haromy, Alois, Cui, Kaisa, Hu, Miao, Yan, Yanan, Zhang, Rui, Michelakis, Evangelos, Chen, Xing-Zhen, Lewis, John D., Tang, Jingfeng, Agellon, Luis B., Michalak, Marek
Publicado 2022

Fasting increases susceptibility to acute myocardial ischaemia/reperfusion injury through a sirtuin-3 mediated increase in fatty acid oxidation

por Hall, Andrew R., Karwi, Qutuba G., Kumar, Sanjeev, Dongworth, Rachel, Aksentijević, Dunja, Altamimi, Tariq R., Fridianto, Kevin Timothy, Chinda, Kroekkiat, Hernandez-Resendiz, Sauri, Mahmood, Mohammad U., Michelakis, Evangelos, Ramachandra, Chrishan J., Ching, Jianhong, Vicencio, Jose M., Shattock, Michael J., Kovalik, Jean-Paul, Yellon, Derek M., Lopaschuk, Gary, Hausenloy, Derek J.
Publicado 2022

Early Start of Oral Clarithromycin Is Associated with Better Outcome in COVID-19 of Moderate Severity: The ACHIEVE Open-Label Single-Arm Trial

por Tsiakos, Konstantinos, Tsakiris, Antonios, Tsibris, Georgios, Voutsinas, Pantazis-Michael, Panagopoulos, Periklis, Kosmidou, Maria, Petrakis, Vasileios, Gravvani, Areti, Gkavogianni, Theologia, Klouras, Eleftherios, Katrini, Konstantina, Koufargyris, Panagiotis, Rapti, Iro, Karageorgos, Athanassios, Vrentzos, Emmanouil, Damoulari, Christina, Zarkada, Vagia, Sidiropoulou, Chrysanthi, Artemi, Sofia, Ioannidis, Anastasios, Papapostolou, Androniki, Michelakis, Evangelos, Georgiopoulou, Maria, Myrodia, Dimitra-Melia, Tsiamalos, Panteleimon, Syrigos, Konstantinos, Chrysos, George, Nitsotolis, Thomas, Milionis, Haralampos, Poulakou, Garyphallia, Giamarellos-Bourboulis, Evangelos J.
Publicado 2021