Alterations in the megakaryocyte transcriptome impacts platelet function in sepsis and COVID-19 infection

por Ajanel, Abigail, Middleton, Elizabeth A.
Publicado 2023

COVID-19–Associated Acute Respiratory Distress Syndrome: Lessons from Tissues and Cells

por Middleton, Elizabeth A., Zimmerman, Guy A.
Publicado 2021

Shedding New Light on Platelet Extracellular Vesicles in Sickle Cell Disease

por Middleton, Elizabeth A., Ware, Lorraine B., Rondina, Matthew T.
Publicado 2020

Cytokine release syndrome in COVID-19: Innate immune, vascular, and platelet pathogenic factors differ in severity of disease and sex

por Petrey, Aaron C, Qeadan, Fares, Middleton, Elizabeth A, Pinchuk, Irina V, Campbell, Robert A, Beswick, Ellen J
Publicado 2020

Comparison of the coagulopathies associated with COVID‐19 and sepsis

por Campbell, Robert A., Hisada, Yohei, Denorme, Frederik, Grover, Steven P., Bouck, Emma G., Middleton, Elizabeth A., Wolberg, Alisa S., Rondina, Matthew T., Mackman, Nigel
Publicado 2021

Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function

por Fidler, Trevor P., Campbell, Robert A., Funari, Trevor, Dunne, Nicholas, Angeles, Enrique Balderas, Middleton, Elizabeth A., Chaudhuri, Dipayan, Weyrich, Andrew S., Abel, E. Dale
Publicado 2017

Eligibility for Posthospitalization Venous Thromboembolism Prophylaxis in Hospitalized Patients With COVID‐19: A Retrospective Cohort Study

por Vaughn, Valerie M., Ratz, David, McLaughlin, Elizabeth S., Horowitz, Jennifer K., Flanders, Scott A., Middleton, Elizabeth A., Grant, Paul J., Kaatz, Scott, Barnes, Geoffrey D.
Publicado 2022

COVID-19 generates hyaluronan fragments that directly induce endothelial barrier dysfunction

por Queisser, Kimberly A., Mellema, Rebecca A., Middleton, Elizabeth A., Portier, Irina, Manne, Bhanu Kanth, Denorme, Frederik, Beswick, Ellen J., Rondina, Matthew T., Campbell, Robert A., Petrey, Aaron C.
Publicado 2021

Tissue factor activity of small and large extracellular vesicles in different diseases

por Sachetto, Ana T.A., Archibald, Sierra J., Hisada, Yohei, Rosell, Axel, Havervall, Sebastian, van Es, Nick, Nieuwland, Rienk, Campbell, Robert A., Middleton, Elizabeth A., Rondina, Matthew T., Thålin, Charlotte, Mackman, Nigel
Publicado 2023

Mucosal-associated invariant T (MAIT) cells mediate protective host responses in sepsis

por Trivedi, Shubhanshi, Labuz, Daniel, Anderson, Cole P, Araujo, Claudia V, Blair, Antoinette, Middleton, Elizabeth A, Jensen, Owen, Tran, Alexander, Mulvey, Matthew A, Campbell, Robert A, Hale, J Scott, Rondina, Matthew T, Leung, Daniel T
Publicado 2020

Platelet gene expression and function in patients with COVID-19

por Manne, Bhanu Kanth, Denorme, Frederik, Middleton, Elizabeth A., Portier, Irina, Rowley, Jesse W., Stubben, Chris, Petrey, Aaron C., Tolley, Neal D., Guo, Li, Cody, Mark, Weyrich, Andrew S., Yost, Christian C., Rondina, Matthew T., Campbell, Robert A.
Publicado 2020

Homogeneous surrogate virus neutralization assay to rapidly assess neutralization activity of anti-SARS-CoV-2 antibodies

por Kim, Sun Jin, Yao, Zhong, Marsh, Morgan C., Eckert, Debra M., Kay, Michael S., Lyakisheva, Anna, Pasic, Maria, Bansal, Aiyush, Birnboim, Chaim, Jha, Prabhat, Galipeau, Yannick, Langlois, Marc-André, Delgado, Julio C., Elgort, Marc G., Campbell, Robert A., Middleton, Elizabeth A., Stagljar, Igor, Owen, Shawn C.
Publicado 2022

IFITM3 regulates fibrinogen endocytosis and platelet reactivity in nonviral sepsis

por Campbell, Robert A., Manne, Bhanu Kanth, Banerjee, Meenakshi, Middleton, Elizabeth A., Ajanel, Abigail, Schwertz, Hansjorg, Denorme, Frederik, Stubben, Chris, Montenont, Emilie, Saperstein, Samantha, Page, Lauren, Tolley, Neal D., Lim, Diana L., Brown, Samuel M., Grissom, Colin K., Sborov, Douglas W., Krishnan, Anandi, Rondina, Matthew T.
Publicado 2022

Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome

por Middleton, Elizabeth A., He, Xue-Yan, Denorme, Frederik, Campbell, Robert A., Ng, David, Salvatore, Steven P., Mostyka, Maria, Baxter-Stoltzfus, Amelia, Borczuk, Alain C., Loda, Massimo, Cody, Mark J., Manne, Bhanu Kanth, Portier, Irina, Harris, Estelle S., Petrey, Aaron C., Beswick, Ellen J., Caulin, Aleah F., Iovino, Anthony, Abegglen, Lisa M., Weyrich, Andrew S., Rondina, Matthew T., Egeblad, Mikala, Schiffman, Joshua D., Yost, Christian Con
Publicado 2020

SARS‐CoV‐2 innate effector associations and viral load in early nasopharyngeal infection

por Liou, Theodore G., Adler, Frederick R., Cahill, Barbara C., Cox, David R., Cox, James E., Grant, Garett J., Hanson, Kimberly E., Hartsell, Stephen C., Hatton, Nathan D., Helms, My N., Jensen, Judy L., Kartsonaki, Christiana, Li, Yanping, Leung, Daniel T., Marvin, James E., Middleton, Elizabeth A., Osburn‐Staker, Sandra M., Packer, Kristyn A., Shakir, Salika M., Sturrock, Anne B., Tardif, Keith D., Warren, Kristi J., Waddoups, Lindsey J., Weaver, Lisa J., Zimmerman, Elizabeth, Paine, Robert
Publicado 2021

Passive Immunity Trial for Our Nation (PassITON): study protocol for a randomized placebo-control clinical trial evaluating COVID-19 convalescent plasma in hospitalized adults

por Self, Wesley H., Stewart, Thomas G., Wheeler, Allison P., El Atrouni, Wissam, Bistran-Hall, Amanda J., Casey, Jonathan D., Cataldo, Vince D., Chappell, James D., Cohn, Claudia S., Collins, Jessica B., Denison, Mark R., de Wit, Maijolein, Dixon, Sheri L., Duggal, Abhijit, Edwards, Terri L., Fontaine, Magali J., Ginde, Adit A., Harkins, Michelle S., Harrington, Thelma, Harris, Estelle S., Hoda, Daanish, Ipe, Tina S., Jaiswal, Stuti J., Johnson, Nicholas J., Jones, Alan E., Laguio-Vila, Maryrose, Lindsell, Christopher J., Mallada, Jason, Mammen, Manoj J., Metcalf, Ryan A., Middleton, Elizabeth A., Mucha, Simon, O’Neal, Hollis R., Pannu, Sonal R., Pulley, Jill M., Qiao, Xian, Raval, Jay S., Rhoads, Jillian P, Schrager, Harry, Shanholtz, Carl, Shapiro, Nathan I., Schrantz, Stephen J., Thomsen, Isaac, Vermillion, Krista K., Bernard, Gordon R., Rice, Todd W.
Publicado 2021

Passive Immunity Trial for Our Nation (PassITON): study protocol for a randomized placebo-control clinical trial evaluating COVID-19 convalescent plasma in hospitalized adults

por Self, Wesley H., Stewart, Thomas G., Wheeler, Allison P., El Atrouni, Wissam, Bistran-Hall, Amanda J., Casey, Jonathan D., Cataldo, Vince D., Chappell, James D., Cohn, Claudia S., Collins, Jessica B., Denison, Mark R., de Wit, Marjolein, Dixon, Sheri L., Duggal, Abhijit, Edwards, Terri L., Fontaine, Magali J., Ginde, Adit A., Harkins, Michelle S., Harrington, Thelma, Harris, Estelle S., Hoda, Daanish, Ipe, Tina S., Jaiswal, Stuti J., Johnson, Nicholas J., Jones, Alan E., Laguio-Vila, Maryrose, Lindsell, Christopher J., Mallada, Jason, Mammen, Manoj J., Metcalf, Ryan A., Middleton, Elizabeth A., Mucha, Simon, O’Neal, Hollis R., Pannu, Sonal R., Pulley, Jill M., Qiao, Xian, Raval, Jay S., Rhoads, Jillian P., Schrager, Harry, Shanholtz, Carl, Shapiro, Nathan I., Schrantz, Stephen J., Thomsen, Isaac, Vermillion, Krista K., Bernard, Gordon R., Rice, Todd W.
Publicado 2021