Degradome-focused RNA interference screens to identify proteases important for breast cancer cell growth

por Hölzen, Lena, Syré, Kerstin, Mitschke, Jan, Brummer, Tilman, Miething, Cornelius, Reinheckel, Thomas
Publicado 2022

RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells

por Hölzen, Lena, Mitschke, Jan, Schönichen, Claudia, Hess, Maria Elena, Ehrenfeld, Sophia, Boerries, Melanie, Miething, Cornelius, Brummer, Tilman, Reinheckel, Thomas
Publicado 2022

Safe and successful teclistamab treatment in very elderly multiple myeloma (MM) patients: a case report and experience from a total of three octogenarians

por Dieterle, Martin Philipp, Mostufi-Zadeh-Haghighi, Gila, Kus, Jan Wilhelm, Wippel, Christopher, Brugger, Zacharias, Miething, Cornelius, Wäsch, Ralph, Engelhardt, Monika
Publicado 2023

Covid‐19 in patients with hematological and solid cancers at a Comprehensive Cancer Center in Germany

por Shoumariyeh, Khalid, Biavasco, Francesca, Ihorst, Gabriele, Rieg, Siegbert, Nieters, Alexandra, Kern, Winfried V., Miething, Cornelius, Duyster, Justus, Engelhardt, Monika, Bertz, Hartmut
Publicado 2020

Longitudinal Multiplexed Measurement of Quantitative Proteomic Signatures in Mouse Lymphoma Models Using Magneto-Nanosensors

por Lee, Jung-Rok, Appelmann, Iris, Miething, Cornelius, Shultz, Tyler O., Ruderman, Daniel, Kim, Dokyoon, Mallick, Parag, Lowe, Scott W., Wang, Shan X.
Publicado 2018

Murine Oncostatin M Has Opposing Effects on the Proliferation of OP9 Bone Marrow Stromal Cells and NIH/3T3 Fibroblasts Signaling through the OSMR

por Jakob, Lena, Müller, Tony Andreas, Rassner, Michael, Kleinfelder, Helen, Veratti, Pia, Mitschke, Jan, Miething, Cornelius, Oostendorp, Robert A. J., Pfeifer, Dietmar, Waterhouse, Miguel, Duyster, Justus
Publicado 2021

Cks1 Is Required for Tumor Cell Proliferation but Not Sufficient to Induce Hematopoietic Malignancies

por Kratzat, Susanne, Nikolova, Viktoriya, Miething, Cornelius, Hoellein, Alexander, Schoeffmann, Stephanie, Gorka, Oliver, Pietschmann, Elke, Illert, Anna-Lena, Ruland, Jürgen, Peschel, Christian, Nilsson, Jonas, Duyster, Justus, Keller, Ulrich
Publicado 2012

NIPA (Nuclear Interaction Partner of ALK) Is Crucial for Effective NPM-ALK Mediated Lymphomagenesis

por Kreutmair, Stefanie, Lippert, Lena Johanna, Klingeberg, Cathrin, Albers-Leischner, Corinna, Yacob, Salome, Shlyakhto, Valeria, Mueller, Tony, Mueller-Rudorf, Alina, Yu, Chuanjiang, Gorantla, Sivahari Prasad, Miething, Cornelius, Duyster, Justus, Illert, Anna Lena
Publicado 2022

The IL-3, IL-5, and GM-CSF common receptor beta chain mediates oncogenic activity of FLT3-ITD-positive AML

por Charlet, Anne, Kappenstein, Max, Keye, Philip, Kläsener, Kathrin, Endres, Cornelia, Poggio, Teresa, Gorantla, Sivahari P., Kreutmair, Stefanie, Sänger, Jana, Illert, Anna L., Miething, Cornelius, Reth, Michael, Duyster, Justus, Rummelt, Christoph, von Bubnoff, Nikolas
Publicado 2021

Multidisciplinary tumor board analysis: validation study of a central tool in tumor centers

por Frank, Benedikt, Ihorst, Gabriele, Herget, Georg, Schäfer, Henning, Neubauer, Jakob, Calba, Marc-Antoine, Textor, Daniel, Möller, Mandy-Deborah, Wenger, Sina, Jung, Johannes, Waldschmidt, Johannes, Miething, Cornelius, Rassner, Michael, Greil, Christine, Wäsch, Ralph, Engelhardt, Monika
Publicado 2022

PTEN action in leukemia dictated by the tissue microenvironment

por Miething, Cornelius, Scuoppo, Claudio, Bosbach, Benedikt, Appelmann, Iris, Nakitandwe, Joy, Ma, Jing, Wu, Gang, Lintault, Laura, Auer, Martina, Premsrirut, Prem K., Teruya-Feldstein, Julie, Hicks, James, Benveniste, Helene, Speicher, Michael R., Downing, James R., Lowe, Scott W.
Publicado 2014

Combination of Lenvatinib and Pembrolizumab Is an Effective Treatment Option for Anaplastic and Poorly Differentiated Thyroid Carcinoma

por Dierks, Christine, Seufert, Jochen, Aumann, Konrad, Ruf, Juri, Klein, Claudius, Kiefer, Selina, Rassner, Michael, Boerries, Melanie, Zielke, Andreas, la Rosee, Paul, Meyer, Philipp Tobias, Kroiss, Matthias, Weißenberger, Christian, Schumacher, Tilmann, Metzger, Patrick, Weiss, Harald, Smaxwil, Constantin, Laubner, Katharina, Duyster, Justus, von Bubnoff, Nikolas, Miething, Cornelius, Thomusch, Oliver
Publicado 2021

Demethylating therapy increases anti-CD123 CAR T cell cytotoxicity against acute myeloid leukemia

por El Khawanky, Nadia, Hughes, Amy, Yu, Wenbo, Myburgh, Renier, Matschulla, Tony, Taromi, Sanaz, Aumann, Konrad, Clarson, Jade, Vinnakota, Janaki Manoja, Shoumariyeh, Khalid, Miething, Cornelius, Lopez, Angel F., Brown, Michael P., Duyster, Justus, Hein, Lutz, Manz, Markus G., Hughes, Timothy P., White, Deborah L., Yong, Agnes S. M., Zeiser, Robert
Publicado 2021

In vivo inducible reverse genetics in patients’ tumors to identify individual therapeutic targets

por Carlet, Michela, Völse, Kerstin, Vergalli, Jenny, Becker, Martin, Herold, Tobias, Arner, Anja, Senft, Daniela, Jurinovic, Vindi, Liu, Wen-Hsin, Gao, Yuqiao, Dill, Veronika, Fehse, Boris, Baldus, Claudia D., Bastian, Lorenz, Lenk, Lennart, Schewe, Denis M., Bagnoli, Johannes W., Vick, Binje, Schmid, Jan Philipp, Wilhelm, Alexander, Marschalek, Rolf, Jost, Philipp J., Miething, Cornelius, Riecken, Kristoffer, Schmidt-Supprian, Marc, Binder, Vera, Jeremias, Irmela
Publicado 2021

Personalized Clinical Decision Making Through Implementation of a Molecular Tumor Board: A German Single-Center Experience

por Hoefflin, Rouven, Geißler, Anna-Lena, Fritsch, Ralph, Claus, Rainer, Wehrle, Julius, Metzger, Patrick, Reiser, Meike, Mehmed, Leman, Fauth, Lisa, Heiland, Dieter Henrik, Erbes, Thalia, Stock, Friedrich, Csanadi, Agnes, Miething, Cornelius, Weddeling, Britta, Meiss, Frank, von Bubnoff, Dagmar, Dierks, Christine, Ge, Isabell, Brass, Volker, Heeg, Steffen, Schäfer, Henning, Boeker, Martin, Rawluk, Justyna, Botzenhart, Elke Maria, Kayser, Gian, Hettmer, Simone, Busch, Hauke, Peters, Christoph, Werner, Martin, Duyster, Justus, Brummer, Tilman, Boerries, Melanie, Lassmann, Silke, von Bubnoff, Nikolas
Publicado 2018

Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma

por Schick, Markus, Zhang, Le, Maurer, Sabine, Maurer, Hans Carlo, Isaakaidis, Konstandina, Schneider, Lara, Patra, Upayan, Schunck, Kathrin, Rohleder, Elena, Hofstetter, Julia, Baluapuri, Apoorva, Scherger, Anna Katharina, Slotta-Huspenina, Julia, Hettler, Franziska, Weber, Julia, Engleitner, Thomas, Maresch, Roman, Slawska, Jolanta, Lewis, Richard, Istvanffy, Rouzanna, Habringer, Stefan, Steiger, Katja, Baiker, Armin, Oostendorp, Robert A. J., Miething, Cornelius, Lenhof, Hans-Peter, Bassermann, Florian, Chapuy, Björn, Wirth, Matthias, Wolf, Elmar, Rad, Roland, Müller, Stefan, Keller, Ulrich
Publicado 2022

Transitioning the Molecular Tumor Board from Proof of Concept to Clinical Routine: A German Single-Center Analysis

por Hoefflin, Rouven, Lazarou, Adriana, Hess, Maria Elena, Reiser, Meike, Wehrle, Julius, Metzger, Patrick, Frey, Anna Verena, Becker, Heiko, Aumann, Konrad, Berner, Kai, Boeker, Martin, Buettner, Nico, Dierks, Christine, Duque-Afonso, Jesus, Eisenblaetter, Michel, Erbes, Thalia, Fritsch, Ralph, Ge, Isabell Xiang, Geißler, Anna-Lena, Grabbert, Markus, Heeg, Steffen, Heiland, Dieter Henrik, Hettmer, Simone, Kayser, Gian, Keller, Alexander, Kleiber, Anita, Kutilina, Alexandra, Mehmed, Leman, Meiss, Frank, Poxleitner, Philipp, Rawluk, Justyna, Ruf, Juri, Schäfer, Henning, Scherer, Florian, Shoumariyeh, Khalid, Tzschach, Andreas, Peters, Christoph, Brummer, Tilman, Werner, Martin, Duyster, Justus, Lassmann, Silke, Miething, Cornelius, Boerries, Melanie, Illert, Anna L., von Bubnoff, Nikolas
Publicado 2021

Molecular and functional profiling identifies therapeutically targetable vulnerabilities in plasmablastic lymphoma

por Frontzek, Fabian, Staiger, Annette M., Zapukhlyak, Myroslav, Xu, Wendan, Bonzheim, Irina, Borgmann, Vanessa, Sander, Philip, Baptista, Maria Joao, Heming, Jan-Niklas, Berning, Philipp, Wullenkord, Ramona, Erdmann, Tabea, Lutz, Mathias, Veratti, Pia, Ehrenfeld, Sophia, Wienand, Kirsty, Horn, Heike, Goodlad, John R., Wilson, Matthew R., Anagnostopoulos, Ioannis, Lamping, Mario, Gonzalez-Barca, Eva, Climent, Fina, Salar, Antonio, Castellvi, Josep, Abrisqueta, Pau, Menarguez, Javier, Aldamiz, Teresa, Richter, Julia, Klapper, Wolfram, Tzankov, Alexandar, Dirnhofer, Stefan, Rosenwald, Andreas, Mate, José Luis, Tapia, Gustavo, Lenz, Peter, Miething, Cornelius, Hartmann, Wolfgang, Chapuy, Björn, Fend, Falko, Ott, German, Navarro, José-Tomas, Grau, Michael, Lenz, Georg
Publicado 2021