Clinicopathologic Conference: A Four‐Year‐Old Child With Digital Clubbing

por Schultz, Katherine, Divanovic, Allison, Towe, Christopher, Miethke, Alexander, Wusik, Katie, Hammill, Adrienne, Brunner, Hermine
Publicado 2021

Associations between MRI T1 mapping, liver stiffness, quantitative MRCP, and laboratory biomarkers in children and young adults with autoimmune liver disease

por Mahalingam, Neeraja, Trout, Andrew T., Gandhi, Deep B., Sahay, Rashmi D., Singh, Ruchi, Miethke, Alexander G., Dillman, Jonathan R.
Publicado 2021

Correction to: Associations between MRI T1 mapping, liver stiffness, quantitative MRCP, and laboratory biomarkers in children and young adults with autoimmune liver disease

por Mahalingam, Neeraja, Trout, Andrew T., Gandhi, Deep B., Sahay, Rashmi D., Singh, Ruchi, Miethke, Alexander G., Dillman, Jonathan R.
Publicado 2022

Clinically available testing options resulting in diagnosis in post-exome clinic at one medical center

por Baker, Elizabeth K., Ulm, Elizabeth A., Belonis, Alyce, Brightman, Diana S., Hallinan, Barbara E., Leslie, Nancy D., Miethke, Alexander G., Vawter-Lee, Marissa, Wu, Yaning, Pena, Loren D. M.
Publicado 2022

Deep Sequencing Reveals Novel Genetic Variants in Children with Acute Liver Failure and Tissue Evidence of Impaired Energy Metabolism

por Valencia, C. Alexander, Wang, Xinjian, Wang, Jin, Peters, Anna, Simmons, Julia R., Moran, Molly C., Mathur, Abhinav, Husami, Ammar, Qian, Yaping, Sheridan, Rachel, Bove, Kevin E., Witte, David, Huang, Taosheng, Miethke, Alexander G.
Publicado 2016

Hepatic MDR3 expression impacts lipid homeostasis and susceptibility to inflammatory bile duct obstruction in neonates

por Carey, Alexandra N., Zhang, Wujuan, Setchell, Kenneth D.R., Simmons, Julia E., Shi, Tiffany, Lages, Celine S., Mullen, Mary, Carroll, Kaitlin, Karns, Rebekah, Bessho, Kazuhiko, Sheridan, Rachel, Zhao, Xueheng, Weber, Susanne N., Miethke, Alexander G.
Publicado 2017

Natural Course of Pediatric Portal Hypertension

por Kassam, Al‐Faraaz, Goddard, Gillian R., Johnston, Michael E., Cortez, Alexander R., Trout, Andrew T., Jenkins, Todd M., Miethke, Alexander G., Campbell, Kathleen M., Bezerra, Jorge A., Balistreri, William F., Nathan, Jaimie D., Alonso, Maria H., Tiao, Gregory M., Bondoc, Alexander J.
Publicado 2020

Serum Matrix Metalloproteinase 7 Is a Diagnostic Biomarker of Biliary Injury and Fibrosis in Pediatric Autoimmune Liver Disease

por Lam, Simon, Singh, Ruchi, Dillman, Jonathan R., Trout, Andrew T., Serai, Suraj D., Sharma, Divya, Sheridan, Rachel, Su, Weizhe, Fei, Lin, Karns, Rebekah, Haramija, Marija M., Ridgway, Ged, Goldfinger, Marc, Squires, James E., Denson, Lee A., Hyams, Jeffery S., Miethke, Alexander G.
Publicado 2020

Maralixibat for the treatment of PFIC: Long‐term, IBAT inhibition in an open‐label, Phase 2 study

por Loomes, Kathleen M., Squires, Robert H., Kelly, Deirdre, Rajwal, Sanjay, Soufi, Nisreen, Lachaux, Alain, Jankowska, Irena, Mack, Cara, Setchell, Kenneth D. R., Karthikeyan, Palaniswamy, Kennedy, Ciara, Dorenbaum, Alejandro, Desai, Nirav K., Garner, Will, Jaecklin, Thomas, Vig, Pamela, Miethke, Alexander, Thompson, Richard J.
Publicado 2022

Sarcopenia is associated with osteopenia and impaired quality of life in children with genetic intrahepatic cholestatic liver disease

por Boster, Julia M., Goodrich, Nathan P., Spino, Cathie, Loomes, Kathleen M., Alonso, Estella M., Kamath, Binita M., Sokol, Ronald J., Karpen, Saul, Miethke, Alexander, Shneider, Benjamin L., Molleston, Jean P., Kohli, Rohit, Horslen, Simon P., Rosenthal, Philip, Valentino, Pamela L., Teckman, Jeffrey H., Hangartner, Thomas N., Sundaram, Shikha S.
Publicado 2023

Risk of variceal hemorrhage and pretransplant mortality in children with biliary atresia

por Bass, Lee M., Ye, Wen, Hawthorne, Kieran, Leung, Daniel H., Murray, Karen F., Molleston, Jean P., Romero, Rene, Karpen, Saul, Rosenthal, Philip, Loomes, Kathleen M., Wang, Kasper S., Squires, Robert H., Miethke, Alexander, Ng, Vicky L., Horslen, Simon, Kyle Jensen, M., Sokol, Ronald J., Magee, John C., Shneider, Benjamin L.
Publicado 2022

Placebo‐Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome

por Shneider, Benjamin L., Spino, Cathie, Kamath, Binita M., Magee, John C., Bass, Lee M., Setchell, Kenneth D., Miethke, Alexander, Molleston, Jean P., Mack, Cara L., Squires, Robert H., Murray, Karen F., Loomes, Kathleen M., Rosenthal, Philip, Karpen, Saul J., Leung, Daniel H., Guthery, Stephen L., Thomas, Danny, Sherker, Averell H., Sokol, Ronald J.
Publicado 2018

Unraveling the Relationship Between Itching, Scratch Scales, and Biomarkers in Children With Alagille Syndrome

por Kamath, Binita M., Spino, Cathie, McLain, Richard, Magee, John C., Fredericks, Emily M., Setchell, Kenneth D., Miethke, Alexander, Molleston, Jean P., Mack, Cara L., Squires, Robert H., Alonso, Estella M., Murray, Karen F., Loomes, Kathleen M., Kyle Jensen, M., Karpen, Saul J., Rosenthal, Philip, Thomas, Danny, Sokol, Ronald J., Shneider, Benjamin L.
Publicado 2020

Impact of long‐term administration of maralixibat on children with cholestasis secondary to Alagille syndrome

por Shneider, Benjamin L., Spino, Catherine A., Kamath, Binita M., Magee, John C., Ignacio, Rosalinda V., Huang, Suiyuan, Horslen, Simon P., Molleston, Jean P., Miethke, Alexander G., Kohli, Rohit, Leung, Daniel H., Jensen, M. Kyle, Loomes, Kathleen M., Karpen, Saul J., Mack, Cara, Rosenthal, Philip, Squires, Robert H., Baker, Alastair, Rajwal, Sanjay, Kelly, Deirdre, Sokol, Ronald J., Thompson, Richard J.
Publicado 2022

Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency

por Li, Chao Zheng, Ogawa, Hiromi, Ng, Soon Seng, Chen, Xindi, Kishimoto, Eriko, Sakabe, Kokoro, Fukami, Aiko, Hu, Yueh-Chiang, Mayhew, Christopher N., Hellmann, Jennifer, Miethke, Alexander, Tasnova, Nahrin L., Blackford, Samuel J.I., Tang, Zu Ming, Syanda, Adam M., Ma, Liang, Xiao, Fang, Sambrotta, Melissa, Tavabie, Oliver, Soares, Filipa, Baker, Oliver, Danovi, Davide, Hayashi, Hisamitsu, Thompson, Richard J., Rashid, S. Tamir, Asai, Akihiro
Publicado 2022

Clinical spectrum and genetic causes of mitochondrial hepatopathy phenotype in children

por Squires, James E., Miethke, Alexander G., Valencia, C. Alexander, Hawthorne, Kieran, Henn, Lisa, Van Hove, Johan L.K., Squires, Robert H., Bove, Kevin, Horslen, Simon, Kohli, Rohit, Molleston, Jean P., Romero, Rene, Alonso, Estella M., Bezerra, Jorge A., Guthery, Stephen L., Hsu, Evelyn, Karpen, Saul J., Loomes, Kathleen M., Ng, Vicky L., Rosenthal, Philip, Mysore, Krupa, Wang, Kasper S., Friederich, Marisa W., Magee, John C., Sokol, Ronald J.
Publicado 2023