High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice(1)(2)(3)(4)(5)

por Christensen, Karen E, Mikael, Leonie G, Leung, Kit-Yi, Lévesque, Nancy, Deng, Liyuan, Wu, Qing, Malysheva, Olga V, Best, Ana, Caudill, Marie A, Greene, Nicholas DE, Rozen, Rima
Publicado 2015

Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas

por Salloum, Ralph, McConechy, Melissa K., Mikael, Leonie G., Fuller, Christine, Drissi, Rachid, DeWire, Mariko, Nikbakht, Hamid, De Jay, Nicolas, Yang, Xiaodan, Boue, Daniel, Chow, Lionel M. L., Finlay, Jonathan L., Gayden, Tenzin, Karamchandani, Jason, Hummel, Trent R., Olshefski, Randal, Osorio, Diana S., Stevenson, Charles, Kleinman, Claudia L., Majewski, Jacek, Fouladi, Maryam, Jabado, Nada
Publicado 2017

Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma

por Nikbakht, Hamid, Panditharatna, Eshini, Mikael, Leonie G., Li, Rui, Gayden, Tenzin, Osmond, Matthew, Ho, Cheng-Ying, Kambhampati, Madhuri, Hwang, Eugene I., Faury, Damien, Siu, Alan, Papillon-Cavanagh, Simon, Bechet, Denise, Ligon, Keith L., Ellezam, Benjamin, Ingram, Wendy J., Stinson, Caedyn, Moore, Andrew S., Warren, Katherine E., Karamchandani, Jason, Packer, Roger J., Jabado, Nada, Majewski, Jacek, Nazarian, Javad
Publicado 2016

TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw

por Gomes, Carolina Cavalieri, Gayden, Tenzin, Bajic, Andrea, Harraz, Osama F., Pratt, Jonathan, Nikbakht, Hamid, Bareke, Eric, Diniz, Marina Gonçalves, Castro, Wagner Henriques, St-Onge, Pascal, Sinnett, Daniel, Han, HyeRim, Rivera, Barbara, Mikael, Leonie G., De Jay, Nicolas, Kleinman, Claudia L., Valera, Elvis Terci, Bassenden, Angelia V., Berghuis, Albert M., Majewski, Jacek, Nelson, Mark T., Gomez, Ricardo Santiago, Jabado, Nada
Publicado 2018

Mutant H3 histones drive human pre-leukemic hematopoietic stem cell expansion and promote leukemic aggressiveness

por Boileau, Meaghan, Shirinian, Margret, Gayden, Tenzin, Harutyunyan, Ashot S., Chen, Carol C. L., Mikael, Leonie G., Duncan, Heather M., Neumann, Andrea L., Arreba-Tutusaus, Patricia, De Jay, Nicolas, Zeinieh, Michele, Rossokhata, Katya, Zhang, Yelu, Nikbakht, Hamid, Mouawad, Carine, Massoud, Radwan, Frey, Felice, Nasr, Rihab, El Cheikh, Jean, El Sabban, Marwan, Kleinman, Claudia L., Mahfouz, Rami, Minden, Mark D., Jabado, Nada, Bazarbachi, Ali, Eppert, Kolja
Publicado 2019

H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis

por Harutyunyan, Ashot S., Krug, Brian, Chen, Haifen, Papillon-Cavanagh, Simon, Zeinieh, Michele, De Jay, Nicolas, Deshmukh, Shriya, Chen, Carol C. L., Belle, Jad, Mikael, Leonie G., Marchione, Dylan M., Li, Rui, Nikbakht, Hamid, Hu, Bo, Cagnone, Gael, Cheung, Warren A., Mohammadnia, Abdulshakour, Bechet, Denise, Faury, Damien, McConechy, Melissa K, Pathania, Manav, Jain, Siddhant U., Ellezam, Benjamin, Weil, Alexander G., Montpetit, Alexandre, Salomoni, Paolo, Pastinen, Tomi, Lu, Chao, Lewis, Peter W., Garcia, Benjamin A., Kleinman, Claudia L., Jabado, Nada, Majewski, Jacek
Publicado 2019

Stalled developmental programs at the root of pediatric brain tumors

por Jessa, Selin, Blanchet-Cohen, Alexis, Krug, Brian, Vladoiu, Maria, Coutelier, Marie, Faury, Damien, Poreau, Brice, De Jay, Nicolas, Hébert, Steven, Monlong, Jean, Farmer, W. Todd, Donovan, Laura K., Hu, Yixing, McConechy, Melissa K., Cavalli, Florence M. G., Mikael, Leonie G., Ellezam, Benjamin, Richer, Maxime, Allaire, Andréa, Weil, Alexander G., Atkinson, Jeffrey, Farmer, Jean-Pierre, Dudley, Roy W. R., Larouche, Valerie, Crevier, Louis, Albrecht, Steffen, Filbin, Mariella G., Sartelet, Hervé, Lutz, Pierre-Eric, Nagy, Corina, Turecki, Gustavo, Costantino, Santiago, Dirks, Peter B., Murai, Keith K., Bourque, Guillaume, Ragoussis, Jiannis, Garzia, Livia, Taylor, Michael D., Jabado, Nada, Kleinman, Claudia L.
Publicado 2019