A molecular switch between the outer and the inner vestibules of the voltage-gated Na(+) channel

por Cervenka, René, Lukács, Péter, Zarrabi, Touran, Koenig, Xaver, Mike, Agnés, Hilber, Karlheinz, Todt, Hannes
Publicado 2010

The permanently charged lidocaine analogue QX222 acts as a blocker from the intracellular side and as an inactivation modulator from the extracellular side in a mutant Na(V)1.4 cha...

por Lukács, Péter, Cervenka, René, Koenig, Xaver, Mike, Agnés, Zarrabi, Touran, Hilber, Karlheinz, Todt, Hannes
Publicado 2010

Differential modulation of rNa(V)1.4 channel inactivated states by lidocaine and its charged analogue QX222

por Lukács, Péter, Cervenka, René, Koenig, Xaver, Mike, Ágnes, Kovar, Michael, Hilber, Karlheinz, Todt, Hannes
Publicado 2011

The anti-addictive drug ibogaine modulates voltage-gated ion channels and may trigger cardiac arrhythmias

por Kovar, Michael, Koenig, Xaver, Mike, Ágnes, Cervenka, René, Lukács, Péter, Todt, Hannes, Sandtner, Walter, Hilber, Karlheinz
Publicado 2011

A conformational change of the domain IV S6 segment of the voltage-gated sodium channel during inactivation

por Gawali, Vaibhavkumar S, Cervenka, René, Lukács, Péter, Koenig, Xaver, Rubi, Lena, Mike, Ágnes K, Hiber, Karlheinz, Todt, Hannes
Publicado 2012

New structural determinants of charged local anaesthetic block of voltage-gated sodium channels

por Lukács, Péter, Cervenka, René, Gawali, Vaibhavkumar S, Koenig, Xaver, Mike, Ágnes K, Rubi, Lena, Hilber, Karlheinz, Todt, Hannes
Publicado 2012

The anti-addiction drug ibogaine inhibits cardiac ion channels: a study to assess the drug’s proarrhythmic potential

por Koenig, Xaver, Kovar, Michael, Rubi, Lena, Mike, Ágnes K, Lukács, Péter, Gawali, Vaibhavkumar S, Todt, Hannes, Sandtner, Walter, Hilber, Karlheinz
Publicado 2012

Anti-addiction drug ibogaine inhibits voltage-gated ionic currents: A study to assess the drug's cardiac ion channel profile()

por Koenig, Xaver, Kovar, Michael, Rubi, Lena, Mike, Agnes K., Lukacs, Peter, Gawali, Vaibhavkumar S., Todt, Hannes, Hilber, Karlheinz, Sandtner, Walter
Publicado 2013

Altered sodium channel function in dystrophin/utrophin-deficient cardiomyocytes

por Koenig, Xaver, Mike, Agnes, Mille, Markus, Cervenka, René, Lukács, Péter, Nagl, Katrin, Dang, Xuan Bach, Todt, Hannes, Bittner, Reginald E, Hilber, Karlheinz
Publicado 2010

Small Molecule Cardiogenol C Upregulates Cardiac Markers and Induces Cardiac Functional Properties in Lineage-Committed Progenitor Cells

por Mike, Agnes K., Koenig, Xaver, Koley, Moumita, Heher, Philipp, Wahl, Gerald, Rubi, Lena, Schnürch, Michael, Mihovilovic, Marko D., Weitzer, Georg, Hilber, Karlheinz
Publicado 2014

Impaired L-type Ca(2+) channel function in the dystrophic heart

por Koenig, Xaver, Dang, Xuan B, Rubi, Lena, Mike, Ágnes K, Lukács, Péter, Cervenka, René, Gawali, Vaibhavkumar S, Todt, Hannes, Bittner, Reginald E, Hilber, Karlheinz
Publicado 2012

Voltage-Gated Ion Channel Dysfunction Precedes Cardiomyopathy Development in the Dystrophic Heart

por Koenig, Xaver, Dysek, Sandra, Kimbacher, Stefanie, Mike, Agnes K., Cervenka, Rene, Lukacs, Peter, Nagl, Katrin, Dang, Xuan B., Todt, Hannes, Bittner, Reginald E., Hilber, Karlheinz
Publicado 2011