Characterization of Active MMP9 in Chronic Inflammatory Diseases Using a Novel Anti-MMP9 Antibody

por Velasquez, Maile, O’Sullivan, Chris, Brockett, Robert, Mikels-Vigdal, Amanda, Mikaelian, Igor, Smith, Victoria, Greenstein, Andrew E.
Publicado 2023

Therapeutic efficacy of anti‐MMP9 antibody in combination with nab‐paclitaxel‐based chemotherapy in pre‐clinical models of pancreatic cancer

por Awasthi, Niranjan, Mikels‐Vigdal, Amanda J., Stefanutti, Erin, Schwarz, Margaret A., Monahan, Sheena, Smith, Victoria, Schwarz, Roderich E.
Publicado 2019

Wnt signaling and Loxl2 promote aggressive osteosarcoma

por Matsuoka, Kazuhiko, Bakiri, Latifa, Wolff, Lena I., Linder, Markus, Mikels-Vigdal, Amanda, Patiño-García, Ana, Lecanda, Fernando, Hartmann, Christine, Sibilia, Maria, Wagner, Erwin F.
Publicado 2020

MMP-9 inhibition promotes anti-tumor immunity through disruption of biochemical and physical barriers to T-cell trafficking to tumors

por Juric, Vladi, O'Sullivan, Chris, Stefanutti, Erin, Kovalenko, Maria, Greenstein, Andrew, Barry-Hamilton, Vivian, Mikaelian, Igor, Degenhardt, Jeremiah, Yue, Peng, Smith, Victoria, Mikels-Vigdal, Amanda
Publicado 2018

Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal

por Ikenaga, Naoki, Peng, Zhen-Wei, Vaid, Kahini A, Liu, Susan B, Yoshida, Shuhei, Sverdlov, Deanna Y, Mikels-Vigdal, Amanda, Smith, Victoria, Schuppan, Detlef, Popov, Yury V
Publicado 2017

TGF beta inhibits HGF, FGF7, and FGF10 expression in normal and IPF lung fibroblasts

por Correll, Kelly A., Edeen, Karen E., Redente, Elizabeth F., Zemans, Rachel L., Edelman, Benjamin L., Danhorn, Thomas, Curran‐Everett, Douglas, Mikels‐Vigdal, Amanda, Mason, Robert J.
Publicado 2018

Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer

por Marshall, Derek C., Lyman, Susan K., McCauley, Scott, Kovalenko, Maria, Spangler, Rhyannon, Liu, Chian, Lee, Michael, O’Sullivan, Christopher, Barry-Hamilton, Vivian, Ghermazien, Haben, Mikels-Vigdal, Amanda, Garcia, Carlos A., Jorgensen, Brett, Velayo, Arleene C., Wang, Ruth, Adamkewicz, Joanne I., Smith, Victoria
Publicado 2015

Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment

por Yang, Jin, Savvatis, Konstantinos, Kang, Jong Seok, Fan, Peidong, Zhong, Hongyan, Schwartz, Karen, Barry, Vivian, Mikels-Vigdal, Amanda, Karpinski, Serge, Kornyeyev, Dmytro, Adamkewicz, Joanne, Feng, Xuhui, Zhou, Qiong, Shang, Ching, Kumar, Praveen, Phan, Dillon, Kasner, Mario, López, Begoña, Diez, Javier, Wright, Keith C., Kovacs, Roxanne L., Chen, Peng-Sheng, Quertermous, Thomas, Smith, Victoria, Yao, Lina, Tschöpe, Carsten, Chang, Ching-Pin
Publicado 2016