Possible Function of Molecular Chaperones in Diseases Caused by Propagating Amyloid Aggregates

por Lazarev, Vladimir F., Mikhaylova, Elena R., Guzhova, Irina V., Margulis, Boris A.
Publicado 2017

Indolylazine Derivative Induces Chaperone Expression in Aged Neural Cells and Prevents the Progression of Alzheimer’s Disease

por Lazarev, Vladimir F., Dutysheva, Elizaveta A., Mikhaylova, Elena R., Trestsova, Maria A., Utepova, Irina A., Chupakhin, Oleg N., Margulis, Boris A., Guzhova, Irina V.
Publicado 2022

Discovery and optimization of cardenolides inhibiting HSF1 activation in human colon HCT-116 cancer cells

por Nikotina, Alina D., Koludarova, Lidia, Komarova, Elena Y., Mikhaylova, Elena R., Aksenov, Nikolay D., Suezov, Roman, Kartzev, Viktor G., Margulis, Boris A., Guzhova, Irina V.
Publicado 2018

Sensitizing tumor cells to conventional drugs: HSP70 chaperone inhibitors, their selection and application in cancer models

por Lazarev, Vladimir F., Sverchinsky, Dmitry V., Mikhaylova, Elena R., Semenyuk, Pavel I., Komarova, Elena Y., Niskanen, Sergey A., Nikotina, Alina D., Burakov, Anton V., Kartsev, Viktor G., Guzhova, Irina V., Margulis, Boris A.
Publicado 2018

Etoposide-Induced Apoptosis in Cancer Cells Can Be Reinforced by an Uncoupled Link between Hsp70 and Caspase-3

por Sverchinsky, Dmitry V., Nikotina, Alina D., Komarova, Elena Y., Mikhaylova, Elena R., Aksenov, Nikolay D., Lazarev, Vladimir F., Mitkevich, Vladimir A., Suezov, Roman, Druzhilovskiy, Dmitry S., Poroikov, Vladimir V., Margulis, Boris A., Guzhova, Irina V.
Publicado 2018

Properties of substances inhibiting aggregation of oxidized GAPDH: Data on the interaction with the enzyme and the impact on its intracellular content

por Lazarev, Vladimir F., Nikotina, Alina D., Semenyuk, Pavel I., Evstafyeva, Diana B., Mikhaylova, Elena R., Muronetz, Vladimir I., Shevtsov, Maxim A., Tolkacheva, Anastasia V., Dobrodumov, Anatoly V., Shavarda, Alexey L., Guzhova, Irina V., Margulis, Boris A.
Publicado 2016

Pyrrolylquinoxaline-2-One Derivative as a Potent Therapeutic Factor for Brain Trauma Rehabilitation

por Dutysheva, Elizaveta A., Mikeladze, Marina A., Trestsova, Maria A., Aksenov, Nikolay D., Utepova, Irina A., Mikhaylova, Elena R., Suezov, Roman V., Charushin, Valery N., Chupakhin, Oleg N., Guzhova, Irina V., Margulis, Boris A., Lazarev, Vladimir F.
Publicado 2020

Extracellular GAPDH Promotes Alzheimer Disease Progression by Enhancing Amyloid-β Aggregation and Cytotoxicity

por Lazarev, Vladimir F, Tsolaki, Magda, Mikhaylova, Elena R, Benken, Konstantin A, Shevtsov, Maxim A, Nikotina, Alina D, Lechpammer, Mirna, Mitkevich, Vladimir A, Makarov, Alexander A, Moskalev, Alexey A, Kozin, Sergey A, Margulis, Boris A, Guzhova, Irina V, Nudler, Evgeny
Publicado 2021

Combination of a Chaperone Synthesis Inducer and an Inhibitor of GAPDH Aggregation for Rehabilitation after Traumatic Brain Injury: A Pilot Study

por Dutysheva, Elizaveta A., Mikhaylova, Elena R., Trestsova, Maria A., Andreev, Alexander I., Apushkin, Danila Yu., Utepova, Irina A., Serebrennikova, Polina O., Akhremenko, Eugenia A., Aksenov, Nikolay D., Bon’, Elizaveta I., Zimatkin, Sergey M., Chupakhin, Oleg N., Margulis, Boris A., Guzhova, Irina V., Lazarev, Vladimir F.
Publicado 2022