Driving DNA transposition by lentiviral protein transduction

por Cai, Yujia, Mikkelsen, Jacob Giehm
Publicado 2014

Prime editing in hematopoietic stem cells—From ex vivo to in vivo CRISPR-based treatment of blood disorders

por Wolff, Jonas Holst, Mikkelsen, Jacob Giehm
Publicado 2023

Delivering genes with human immunodeficiency virus-derived vehicles: still state-of-the-art after 25 years

por Wolff, Jonas Holst, Mikkelsen, Jacob Giehm
Publicado 2022

Targeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleases

por Cai, Yujia, Bak, Rasmus O, Mikkelsen, Jacob Giehm
Publicado 2014

DNA transposon-based gene vehicles - scenes from an evolutionary drive

por Skipper, Kristian Alsbjerg, Andersen, Peter Refsing, Sharma, Nynne, Mikkelsen, Jacob Giehm
Publicado 2013

Regulated gene insertion by steroid-induced ΦC31 integrase

por Sharma, Nynne, Moldt, Brian, Dalsgaard, Trine, Jensen, Thomas G., Mikkelsen, Jacob Giehm
Publicado 2008

Sustained transgene expression from sleeping beauty DNA transposons containing a core fragment of the HNRPA2B1-CBX3 ubiquitous chromatin opening element (UCOE)

por Skipper, Kristian Alsbjerg, Hollensen, Anne Kruse, Antoniou, Michael N., Mikkelsen, Jacob Giehm
Publicado 2019

piggyPrime: High-Efficacy Prime Editing in Human Cells Using piggyBac-Based DNA Transposition

por Wolff, Jonas Holst, Haldrup, Jakob, Thomsen, Emil Aagaard, Andersen, Sofie, Mikkelsen, Jacob Giehm
Publicado 2021

pegIT - a web-based design tool for prime editing

por Anderson, Mads Valdemar, Haldrup, Jakob, Thomsen, Emil Aagaard, Wolff, Jonas Holst, Mikkelsen, Jacob Giehm
Publicado 2021

Efficient Sleeping Beauty DNA Transposition From DNA Minicircles

por Sharma, Nynne, Cai, Yujia, Bak, Rasmus O, Jakobsen, Martin R, Schrøder, Lisbeth Dahl, Mikkelsen, Jacob Giehm
Publicado 2013

CRISPR-Cas9-directed gene tagging using a single integrase-defective lentiviral vector carrying a transposase-based Cas9 off switch

por Thomsen, Emil Aagaard, Skipper, Kristian Alsbjerg, Andersen, Sofie, Haslund, Didde, Skov, Thomas Wisbech, Mikkelsen, Jacob Giehm
Publicado 2022

The Impact of cHS4 Insulators on DNA Transposon Vector Mobilization and Silencing in Retinal Pigment Epithelium Cells

por Sharma, Nynne, Hollensen, Anne Kruse, Bak, Rasmus O., Staunstrup, Nicklas Heine, Schrøder, Lisbeth Dahl, Mikkelsen, Jacob Giehm
Publicado 2012

Time-Restricted PiggyBac DNA Transposition by Transposase Protein Delivery Using Lentivirus-Derived Nanoparticles

por Skipper, Kristian Alsbjerg, Nielsen, Mathias Gaarde, Andersen, Sofie, Ryø, Laura Barrett, Bak, Rasmus O., Mikkelsen, Jacob Giehm
Publicado 2018

Single-Cell Monitoring of Activated Innate Immune Signaling by a d2eGFP-Based Reporter Mimicking Time-Restricted Activation of IFNB1 Expression

por Thomsen, Emil Aagaard, Andersen, Sofie, Marqvorsen, Mikkel Haarslev Schröder, Skipper, Kristian Alsbjerg, Paludan, Søren R., Mikkelsen, Jacob Giehm
Publicado 2022

Anti-Apoptotic Effects of Lentiviral Vector Transduction Promote Increased Rituximab Tolerance in Cancerous B-Cells

por Ranjbar, Benyamin, Krogh, Louise Bechmann, Laursen, Maria Bach, Primo, Maria Nascimento, Marques, Sara Correia, Dybkær, Karen, Mikkelsen, Jacob Giehm
Publicado 2016

Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma

por Thomsen, Emil Aagaard, Rovsing, Anne Bruun, Anderson, Mads Valdemar, Due, Hanne, Huang, Jinrong, Luo, Yonglun, Dybkær, Karen, Mikkelsen, Jacob Giehm
Publicado 2020

Targeted Knockout of the Vegfa Gene in the Retina by Subretinal Injection of RNP Complexes Containing Cas9 Protein and Modified sgRNAs

por Holmgaard, Andreas Braae, Askou, Anne Louise, Jensen, Emilie Grarup, Alsing, Sidsel, Bak, Rasmus O., Mikkelsen, Jacob Giehm, Corydon, Thomas J.
Publicado 2021

Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy

por Askou, Anne Louise, Alsing, Sidsel, Benckendorff, Josephine N.E., Holmgaard, Andreas, Mikkelsen, Jacob Giehm, Aagaard, Lars, Bek, Toke, Corydon, Thomas J.
Publicado 2019

A Sleeping Beauty DNA transposon-based genetic sensor for functional screening of vitamin D3 analogues

por Staunstrup, Nicklas H, Sharma, Nynne, Bak, Rasmus O, Svensson, Lars, Petersen, Thomas K, Aarenstrup, Lene, Kristiansen, Karsten, Bolund, Lars, Mikkelsen, Jacob Giehm
Publicado 2011

DNA transposition by protein transduction of the piggyBac transposase from lentiviral Gag precursors

por Cai, Yujia, Bak, Rasmus O., Krogh, Louise Bechmann, Staunstrup, Nicklas H., Moldt, Brian, Corydon, Thomas J., Schrøder, Lisbeth Dahl, Mikkelsen, Jacob Giehm
Publicado 2014