Biophysical methods in early drug discovery

por Holdgate, Geoffrey, Embrey, Kevin, Milbradt, Alexander, Davies, Gareth
Publicado 2019

Segmental Isotope Labelling of an Individual Bromodomain of a Tandem Domain BRD4 Using Sortase A

por Williams, Felix P., Milbradt, Alexander G., Embrey, Kevin J., Bobby, Romel
Publicado 2016

Bromodomain Interactions with Acetylated Histone 4 Peptides in the BRD4 Tandem Domain: Effects on Domain Dynamics and Internal Flexibility

por Wernersson, Sven, Bobby, Romel, Flavell, Liz, Milbradt, Alexander G., Holdgate, Geoffrey A., Embrey, Kevin J., Akke, Mikael
Publicado 2022

Structure of the VP16 Transactivator Target in ARC/Mediator

por Milbradt, Alexander G., Kulkarni, Madhura, Yi, Tingfang, Takeuchi, Koh, Sun, Zhen-Yu J., Luna, Rafael E., Selenko, Philipp, Näär, Anders M., Wagner, Gerhard
Publicado 2011

NMR Molecular Replacement Provides New Insights into Binding Modes to Bromodomains of BRD4 and TRIM24

por Torres, Felix, Walser, Reto, Kaderli, Janina, Rossi, Emanuele, Bobby, Romel, Packer, Martin J., Sarda, Sunil, Walker, Graeme, Hitchin, James R., Milbradt, Alexander G., Orts, Julien
Publicado 2022