Heritable aortic root aneurysms

por Ouzounian, Maral, LeMaire, Scott A., Milewicz, Dianna M.
Publicado 2023

4573 Characterization of vascular disease in an Acta2 mutant mouse model

por Kaw, Anita, Kwartler, Callie, Chattopadhyay, Abhijnan, Milewicz, Dianna M.
Publicado 2020

Diabetes and Reduced Risk for Thoracic Aortic Aneurysms and Dissections: A Nationwide Case-Control Study

por Prakash, Siddharth K., Pedroza, Claudia, Khalil, Yameen A., Milewicz, Dianna M.
Publicado 2012

Risk Factors for Thoracic Aortic Dissection

por Zhou, Zhen, Cecchi, Alana C., Prakash, Siddharth K., Milewicz, Dianna M.
Publicado 2022

Preventing Acute Aortic Dissections: The Power of Familial Screening and Risk Assessment

por Cecchi, Alana C., Boerio, Maura L., Marin, Isabella, Pinard, Amélie, Milewicz, Dianna M.
Publicado 2022

Genetic approaches to identify pathological limitations in aortic smooth muscle contraction

por Huang, Jian, Gao, Ning, Wang, Shanzhi, Milewicz, Dianna M., Kamm, Kristine E., Stull, James T.
Publicado 2018

Patient-Specific Modeling Could Predict Occurrence of Pediatric Stroke

por Horn, John D., Johnson, Michael J., Starosolski, Zbigniew, Meoded, Avner, Milewicz, Dianna M., Annapragada, Ananth, Hossain, Shaolie S.
Publicado 2022

Ultra High-Resolution In vivo Computed Tomography Imaging of Mouse Cerebrovasculature Using a Long Circulating Blood Pool Contrast Agent

por Starosolski, Zbigniew, Villamizar, Carlos A., Rendon, David, Paldino, Michael J., Milewicz, Dianna M., Ghaghada, Ketan B., Annapragada, Ananth V.
Publicado 2015

Current state and future directions of genomic medicine in aortic dissection: A path to prevention and personalized care

por Cecchi, Alana C., Drake, Madeline, Campos, Chrisanne, Howitt, Jake, Medina, Jonathan, Damrauer, Scott M., Shalhub, Sherene, Milewicz, Dianna M.
Publicado 2022

Smooth muscle α-actin missense variant promotes atherosclerosis through modulation of intracellular cholesterol in smooth muscle cells

por Kaw, Kaveeta, Chattopadhyay, Abhijnan, Guan, Pujun, Chen, Jiyuan, Majumder, Suravi, Duan, Xue-yan, Ma, Shuangtao, Zhang, Chen, Kwartler, Callie S, Milewicz, Dianna M
Publicado 2023

Vertebral artery tortuosity in Turner syndrome: is tortuosity a component of the aortopathy phenotype?

por Morris, Shaine A, Payne, William A, Lacro, Ronald V, Maskatia, Shiraz A, Masand, Prakash, Noel, Cory V, Milewicz, Dianna M, Krishnamurthy, Rajesh
Publicado 2014

Arterial tortuosity and change with age in young patients with aortopathy

por Morris, Shaine A, Payne, William A, Sami, Sarah, Wang, Yunfei, LeMaire, Scott A, Tyson, Jon E, Krishnamurthy, Rajesh, Milewicz, Dianna M
Publicado 2015

Cholesterol-Induced Phenotypic Modulation of Smooth Muscle Cells to Macrophage/Fibroblast–like Cells Is Driven by an Unfolded Protein Response

por Chattopadhyay, Abhijnan, Kwartler, Callie S., Kaw, Kaveeta, Li, Yanming, Kaw, Anita, Chen, Jiyuan, LeMaire, Scott A., Shen, Ying H., Milewicz, Dianna M.
Publicado 2020

Proteomic analysis of descending thoracic aorta identifies unique and universal signatures of aneurysm and dissection

por Saddic, Louis, Orosco, Amanda, Guo, Dongchuan, Milewicz, Dianna M., Troxlair, Dana, Heide, Richard Vander, Herrington, David, Wang, Yue, Azizzadeh, Ali, Parker, Sarah J.
Publicado 2022

Smooth Muscle-Alpha Actin R149C Pathogenic Variant Downregulates Integrin Recruitment at Cell-Matrix Adhesions and Decreases Cellular Contractility

por Ojha, Krishna R., Kim, Hyoseon, Padgham, Samuel, Hopkins, Laura, Zamen, Robert J., Chattopadhyay, Abhijnan, Han, Gang, Milewicz, Dianna M., Massett, Michael P., Trache, Andreea
Publicado 2023

A Marfan syndrome gene expression phenotype in cultured skin fibroblasts

por Yao, Zizhen, Jaeger, Jochen C, Ruzzo, Walter L, Morale, Cecile Z, Emond, Mary, Francke, Uta, Milewicz, Dianna M, Schwartz, Stephen M, Mulvihill, Eileen R
Publicado 2007

IL‐6 Regulates Extracellular Matrix Remodeling Associated With Aortic Dilation in a Fibrillin‐1 Hypomorphic mgR/mgR Mouse Model of Severe Marfan Syndrome

por Ju, Xiaoxi, Ijaz, Talha, Sun, Hong, LeJeune, Wanda, Vargas, Gracie, Shilagard, Tuya, Recinos, Adrian, Milewicz, Dianna M., Brasier, Allan R., Tilton, Ronald G.
Publicado 2014

The defining pathology of the new clinical and histopathologic entity ACTA2-related cerebrovascular disease

por Georgescu, Maria-Magdalena, Pinho, Marco da Cunha, Richardson, Timothy E., Torrealba, Jose, Buja, L. Maximilian, Milewicz, Dianna M., Raisanen, Jack M., Burns, Dennis K.
Publicado 2015

Rare deleterious variants of NOTCH1, GATA4, SMAD6, and ROBO4 are enriched in BAV with early onset complications but not in BAV with heritable thoracic aortic disease

por Musfee, Fadi I., Guo, Dongchuan, Pinard, Amélie C., Hostetler, Ellen M., Blue, Elizabeth E., Nickerson, Deborah A., Bamshad, Michael J., Milewicz, Dianna M., Prakash, Siddharth K.
Publicado 2020

Critical Role of ADAMTS-4 in the Development of Sporadic Aortic Aneurysm and Dissection in Mice

por Ren, Pingping, Hughes, Michael, Krishnamoorthy, Swapna, Zou, Sili, Zhang, Lin, Wu, Darrell, Zhang, Chen, Curci, John A., Coselli, Joseph S., Milewicz, Dianna M., LeMaire, Scott A., Shen, Ying H.
Publicado 2017