Exploring and Targeting the Tumor Immune Microenvironment of Neuroblastoma

por Masih, Katherine E., Wei, Jun S., Milewski, David, Khan, Javed
Publicado 2021

FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts

por Black, Markaisa, Milewski, David, Le, Tien, Ren, Xiaomeng, Xu, Yan, Kalinichenko, Vladimir V., Kalin, Tanya V.
Publicado 2018

FoxF1 and FoxF2 transcription factors synergistically promote Rhabdomyosarcoma carcinogenesis by repressing transcription of p21(Cip1) CDK inhibitor

por Milewski, David, Pradhan, Arun, Wang, Xinjian, Cai, Yuqi, Le, Tien, Turpin, Brian, Kalinichenko, Vladimir V., Kalin, Tanya V.
Publicado 2016

FOXM1 nuclear transcription factor translocates into mitochondria and inhibits oxidative phosphorylation

por Black, Markaisa, Arumugam, Paritha, Shukla, Samriddhi, Pradhan, Arun, Ustiyan, Vladimir, Milewski, David, Kalinichenko, Vladimir V., Kalin, Tanya V.
Publicado 2020

Loss of FOXM1 in macrophages promotes pulmonary fibrosis by activating p38 MAPK signaling pathway

por Goda, Chinmayee, Balli, David, Black, Markaisa, Milewski, David, Le, Tien, Ustiyan, Vladimir, Ren, Xiaomeng, Kalinichenko, Vladimir V., Kalin, Tanya V.
Publicado 2020

FOXM1 activates AGR2 and causes progression of lung adenomas into invasive mucinous adenocarcinomas

por Milewski, David, Balli, David, Ustiyan, Vladimir, Le, Tien, Dienemann, Hendrik, Warth, Arne, Breuhahn, Kai, Whitsett, Jeffrey A., Kalinichenko, Vladimir V., Kalin, Tanya V.
Publicado 2017

IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models

por Gasilina, Anjelika, Premnauth, Gurdat, Gurjar, Purujit, Biesiada, Jacek, Hegde, Shailaja, Milewski, David, Ma, Gang, Kalin, Tanya V., Merino, Edward, Meller, Jarek, Seibel, William, Cancelas, José A., Vinnedge, Lisa Privette, Nassar, Nicolas N.
Publicado 2020

Proteogenomic Analysis Unveils the HLA Class I-Presented Immunopeptidome in Melanoma and EGFR-Mutant Lung Adenocarcinoma

por Qi, Yue A., Maity, Tapan K., Cultraro, Constance M., Misra, Vikram, Zhang, Xu, Ade, Catherine, Gao, Shaojian, Milewski, David, Nguyen, Khoa D., Ebrahimabadi, Mohammad H., Hanada, Ken-ichi, Khan, Javed, Sahinalp, Cenk, Yang, James C., Guha, Udayan
Publicado 2021

Lung endothelial cells regulate pulmonary fibrosis through FOXF1/R-Ras signaling

por Bian, Fenghua, Lan, Ying-Wei, Zhao, Shuyang, Deng, Zicheng, Shukla, Samriddhi, Acharya, Anusha, Donovan, Johnny, Le, Tien, Milewski, David, Bacchetta, Matthew, Hozain, Ahmed Emad, Tipograf, Yuliya, Chen, Ya-Wen, Xu, Yan, Shi, Donglu, Kalinichenko, Vladimir V., Kalin, Tanya V.
Publicado 2023

FOXF1 is required for the oncogenic properties of PAX3-FOXO1 in rhabdomyosarcoma.

por Milewski, David, Shukla, Samriddhi, Gryder, Berkley E., Pradhan, Arun, Donovan, Johnny, Sudha, Parvathi, Vallabh, Sushmitha, Pyros, Athena, Xu, Yan, Barski, Artem, Szabo, Sara, Turpin, Brian, Pressey, Joseph G., Millay, Douglas P., Khan, Javed, Kalinichenko, Vladimir V., Kalin, Tanya V.
Publicado 2021

An optimized bicistronic chimeric antigen receptor against GPC2 or CD276 overcomes heterogeneous expression in neuroblastoma

por Tian, Meijie, Cheuk, Adam T., Wei, Jun S., Abdelmaksoud, Abdalla, Chou, Hsien-Chao, Milewski, David, Kelly, Michael C., Song, Young K., Dower, Christopher M., Li, Nan, Qin, Haiying, Kim, Yong Yean, Wu, Jerry T., Wen, Xinyu, Benzaoui, Mehdi, Masih, Katherine E., Wu, Xiaolin, Zhang, Zhongmei, Badr, Sherif, Taylor, Naomi, Croix, Brad St., Ho, Mitchell, Khan, Javed
Publicado 2022

Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma

por Pomella, Silvia, Sreenivas, Prethish, Gryder, Berkley E., Wang, Long, Milewski, David, Cassandri, Matteo, Baxi, Kunal, Hensch, Nicole R., Carcarino, Elena, Song, Young, Chou, Hsien-Chao, Yohe, Marielle E., Stanton, Benjamin Z., Amadio, Bruno, Caruana, Ignazio, De Stefanis, Cristiano, De Vito, Rita, Locatelli, Franco, Chen, Yidong, Chen, Eleanor Y., Houghton, Peter, Khan, Javed, Rota, Rossella, Ignatius, Myron S.
Publicado 2021

Preclinical Evaluation of the FGFR-Family Inhibitor Futibatinib for Pediatric Rhabdomyosarcoma

por Wu, Jerry T., Cheuk, Adam, Isanogle, Kristine, Robinson, Christina, Zhang, Xiaohu, Ceribelli, Michele, Beck, Erin, Shinn, Paul, Klumpp-Thomas, Carleen, Wilson, Kelli M., McKnight, Crystal, Itkin, Zina, Sotome, Hiroshi, Hirai, Hiroshi, Calleja, Elizabeth, Wacheck, Volker, Gouker, Brad, Peer, Cody J., Corvalan, Natalia, Milewski, David, Kim, Yong Y., Figg, William D., Edmondson, Elijah F., Thomas, Craig J., Difilippantonio, Simone, Wei, Jun S., Khan, Javed
Publicado 2023

Predicting Molecular Subtype and Survival of Rhabdomyosarcoma Patients Using Deep Learning of H&E Images: A Report from the Children's Oncology Group

por Milewski, David, Jung, Hyun, Brown, G. Thomas, Liu, Yanling, Somerville, Ben, Lisle, Curtis, Ladanyi, Marc, Rudzinski, Erin R., Choo-Wosoba, Hyoyoung, Barkauskas, Donald A., Lo, Tammy, Hall, David, Linardic, Corinne M., Wei, Jun S., Chou, Hsien-Chao, Skapek, Stephen X., Venkatramani, Rajkumar, Bode, Peter K., Steinberg, Seth M., Zaki, George, Kuznetsov, Igor B., Hawkins, Douglas S., Shern, Jack F., Collins, Jack, Khan, Javed
Publicado 2023

A stem cell epigenome is associated with primary nonresponse to CD19 CAR T cells in pediatric acute lymphoblastic leukemia

por Masih, Katherine E., Gardner, Rebecca A., Chou, Hsien-Chao, Abdelmaksoud, Abdalla, Song, Young K., Mariani, Luca, Gangalapudi, Vineela, Gryder, Berkley E., Wilson, Ashley L., Adebola, Serifat O., Stanton, Benjamin Z., Wang, Chaoyu, Milewski, David, Kim, Yong Yean, Tian, Meijie, Cheuk, Adam Tai-Chi, Wen, Xinyu, Zhang, Yue, Altan-Bonnet, Grégoire, Kelly, Michael C., Wei, Jun S., Bulyk, Martha L., Jensen, Michael C., Orentas, Rimas J., Khan, Javed
Publicado 2023

Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma

por Tian, Meijie, Wei, Jun S., Shivaprasad, Nityashree, Highfill, Steven L., Gryder, Berkley E., Milewski, David, Brown, G. Tom, Moses, Larry, Song, Hannah, Wu, Jerry T., Azorsa, Peter, Kumar, Jeetendra, Schneider, Dina, Chou, Hsien-Chao, Song, Young K., Rahmy, Abdelrahman, Masih, Katherine E., Kim, Yong Yean, Belyea, Brian, Linardic, Corinne M., Dropulic, Boro, Sullivan, Peter M., Sorensen, Poul H., Dimitrov, Dimiter S., Maris, John M., Mackall, Crystal L., Orentas, Rimas J., Cheuk, Adam T., Khan, Javed
Publicado 2023

Immuno-transcriptomic profiling of extracranial pediatric solid malignancies

por Brohl, Andrew S., Sindiri, Sivasish, Wei, Jun S., Milewski, David, Chou, Hsien-Chao, Song, Young K., Wen, Xinyu, Kumar, Jeetendra, Reardon, Hue V., Mudunuri, Uma S., Collins, Jack R., Nagaraj, Sushma, Gangalapudi, Vineela, Tyagi, Manoj, Zhu, Yuelin J., Masih, Katherine E., Yohe, Marielle E., Shern, Jack F., Qi, Yue, Guha, Udayan, Catchpoole, Daniel, Orentas, Rimas J., Kuznetsov, Igor B., Llosa, Nicolas J., Ligon, John A., Turpin, Brian K., Leino, Daniel G., Iwata, Shintaro, Andrulis, Irene L., Wunder, Jay S., Toledo, Silvia R.C., Meltzer, Paul S., Lau, Ching, Teicher, Beverly A., Magnan, Heather, Ladanyi, Marc, Khan, Javed
Publicado 2021