Polycystic kidney disease: The cilia mechanosensation debate gets (bio)physical

por Wachten, Dagmar, Mill, Pleasantine
Publicado 2023

Primary cilia as dynamic and diverse signalling hubs in development and disease

por Mill, Pleasantine, Christensen, Søren T., Pedersen, Lotte B.
Publicado 2023

Ciliary dynein motor preassembly is regulated by Wdr92 in association with HSP90 co-chaperone, R2TP

por zur Lage, Petra, Stefanopoulou, Panagiota, Styczynska-Soczka, Katarzyna, Quinn, Niall, Mali, Girish, von Kriegsheim, Alex, Mill, Pleasantine, Jarman, Andrew P.
Publicado 2018

Acute Versus Chronic Loss of Mammalian Azi1/Cep131 Results in Distinct Ciliary Phenotypes

por Hall, Emma A., Keighren, Margaret, Ford, Matthew J., Davey, Tracey, Jarman, Andrew P., Smith, Lee B., Jackson, Ian J., Mill, Pleasantine
Publicado 2013

Palmitoylation Regulates Epidermal Homeostasis and Hair Follicle Differentiation

por Mill, Pleasantine, Lee, Angela W. S., Fukata, Yuko, Tsutsumi, Ryouhei, Fukata, Masaki, Keighren, Margaret, Porter, Rebecca M., McKie, Lisa, Smyth, Ian, Jackson, Ian J.
Publicado 2009

Gelsolin dysfunction causes photoreceptor loss in induced pluripotent cell and animal retinitis pigmentosa models

por Megaw, Roly, Abu-Arafeh, Hashem, Jungnickel, Melissa, Mellough, Carla, Gurniak, Christine, Witke, Walter, Zhang, Wei, Khanna, Hemant, Mill, Pleasantine, Dhillon, Baljean, Wright, Alan F., Lako, Majlinda, ffrench-Constant, Charles
Publicado 2017

Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function

por Haward, Fiona, Maslon, Magdalena M, Yeyati, Patricia L, Bellora, Nicolas, Hansen, Jan N, Aitken, Stuart, Lawson, Jennifer, von Kriegsheim, Alex, Wachten, Dagmar, Mill, Pleasantine, Adams, Ian R, Caceres, Javier F
Publicado 2021

A WDR35-dependent coat protein complex transports ciliary membrane cargo vesicles to cilia

por Quidwai, Tooba, Wang, Jiaolong, Hall, Emma A, Petriman, Narcis A, Leng, Weihua, Kiesel, Petra, Wells, Jonathan N, Murphy, Laura C, Keighren, Margaret A, Marsh, Joseph A, Lorentzen, Esben, Pigino, Gaia, Mill, Pleasantine
Publicado 2021

KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability

por Yeyati, Patricia L., Schiller, Rachel, Mali, Girish, Kasioulis, Ioannis, Kawamura, Akane, Adams, Ian R., Playfoot, Christopher, Gilbert, Nick, van Heyningen, Veronica, Wills, Jimi, von Kriegsheim, Alex, Finch, Andrew, Sakai, Juro, Schofield, Christopher J., Jackson, Ian J., Mill, Pleasantine
Publicado 2017

ZMYND10 functions in a chaperone relay during axonemal dynein assembly

por Mali, Girish R, Yeyati, Patricia L, Mizuno, Seiya, Dodd, Daniel O, Tennant, Peter A, Keighren, Margaret A, zur Lage, Petra, Shoemark, Amelia, Garcia-Munoz, Amaya, Shimada, Atsuko, Takeda, Hiroyuki, Edlich, Frank, Takahashi, Satoru, von Kreigsheim, Alex, Jarman, Andrew P, Mill, Pleasantine
Publicado 2018

A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice

por Ford, Matthew J., Yeyati, Patricia L., Mali, Girish R., Keighren, Margaret A., Waddell, Scott H., Mjoseng, Heidi K., Douglas, Adam T., Hall, Emma A., Sakaue-Sawano, Asako, Miyawaki, Atsushi, Meehan, Richard R., Boulter, Luke, Jackson, Ian J., Mill, Pleasantine, Mort, Richard L.
Publicado 2018

A TGFβ-ECM-Integrin signalling axis drives structural reconfiguration of the bile duct to promote polycystic liver disease

por Waddell, Scott H, Yao, Yuelin, Olaizola, Paula, Walker, Alexander, Jarman, Edward J, Gournopanos, Konstantinos, Gradinaru, Andreea, Christodoulou, Ersi, Gautier, Philippe, Boerrigter, Melissa M, Cadamuro, Massimiliano, Fabris, Luca, Drenth, Joost PH, Kendall, Timothy J, Banales, Jesus M, Khamseh, Ava, Mill, Pleasantine, Boulter, Luke
Publicado 2023

Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development

por Reijns, Martin A.M., Rabe, Björn, Rigby, Rachel E., Mill, Pleasantine, Astell, Katy R., Lettice, Laura A., Boyle, Shelagh, Leitch, Andrea, Keighren, Margaret, Kilanowski, Fiona, Devenney, Paul S., Sexton, David, Grimes, Graeme, Holt, Ian J., Hill, Robert E., Taylor, Martin S., Lawson, Kirstie A., Dorin, Julia R., Jackson, Andrew P.
Publicado 2012

In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma

por Younger, Nicholas T., Wilson, Mollie L., Martinez Lyons, Anabel, Jarman, Edward J., Meynert, Alison M., Grimes, Graeme R., Gournopanos, Konstantinos, Waddell, Scott H., Tennant, Peter A., Wilson, David H., Guest, Rachel V., Wigmore, Stephen J., Acosta, Juan Carlos, Kendall, Timothy J., Taylor, Martin S., Sproul, Duncan, Mill, Pleasantine, Boulter, Luke
Publicado 2022

Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis

por Hall, Emma A, Kumar, Dhivya, Prosser, Suzanna L, Yeyati, Patricia L, Herranz-Pérez, Vicente, García-Verdugo, Jose Manuel, Rose, Lorraine, McKie, Lisa, Dodd, Daniel O, Tennant, Peter A, Megaw, Roly, Murphy, Laura C, Ferreira, Marisa F, Grimes, Graeme, Williams, Lucy, Quidwai, Tooba, Pelletier, Laurence, Reiter, Jeremy F, Mill, Pleasantine
Publicado 2023

The effect of Dnaaf5 gene dosage on primary ciliary dyskinesia phenotypes

por Horani, Amjad, Gupta, Deepesh Kumar, Xu, Jian, Xu, Huihui, del Carmen Puga-Molina, Lis, Santi, Celia M., Ramagiri, Sruthi, Brennan, Steven K., Pan, Jiehong, Koenitzer, Jeffrey R., Huang, Tao, Hyland, Rachael M., Gunsten, Sean P., Tzeng, Shin-Cheng, Strahle, Jennifer M., Mill, Pleasantine, Mahjoub, Moe R., Dutcher, Susan K., Brody, Steven L.
Publicado 2023

TALPID3 controls centrosome and cell polarity and the human ortholog KIAA0586 is mutated in Joubert syndrome (JBTS23)

por Stephen, Louise A, Tawamie, Hasan, Davis, Gemma M, Tebbe, Lars, Nürnberg, Peter, Nürnberg, Gudrun, Thiele, Holger, Thoenes, Michaela, Boltshauser, Eugen, Uebe, Steffen, Rompel, Oliver, Reis, André, Ekici, Arif B, McTeir, Lynn, Fraser, Amy M, Hall, Emma A, Mill, Pleasantine, Daudet, Nicolas, Cross, Courtney, Wolfrum, Uwe, Jamra, Rami Abou, Davey, Megan G, Bolz, Hanno J
Publicado 2015

Proceedings of the 4(th) BEAT-PCD Conference and 5(th) PCD Training School

por Gardner, Laura E., Horton, Katie L., Shoemark, Amelia, Lucas, Jane S., Nielsen, Kim G., Kobbernagel, Helene, Rubbo, Bruna, Hirst, Robert A., Kouis, Panayiotis, Ullmann, Nicola, Reula, Ana, Rumman, Nisreen, Mitchison, Hannah M., Pinto, Andreia, Richardson, Charlotte, Schmidt, Anne, Thompson, James, Gaupmann, René, Dabrowski, Maciej, Mill, Pleasantine, Carr, Siobhan B., Norris, Dominic P., Kuehni, Claudia E., Goutaki, Myrofora, Hogg, Claire
Publicado 2020

HEATR2 Plays a Conserved Role in Assembly of the Ciliary Motile Apparatus

por Diggle, Christine P., Moore, Daniel J., Mali, Girish, zur Lage, Petra, Ait-Lounis, Aouatef, Schmidts, Miriam, Shoemark, Amelia, Garcia Munoz, Amaya, Halachev, Mihail R., Gautier, Philippe, Yeyati, Patricia L., Bonthron, David T., Carr, Ian M., Hayward, Bruce, Markham, Alexander F., Hope, Jilly E., von Kriegsheim, Alex, Mitchison, Hannah M., Jackson, Ian J., Durand, Bénédicte, Reith, Walter, Sheridan, Eamonn, Jarman, Andrew P., Mill, Pleasantine
Publicado 2014

PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins

por Hall, Emma A., Nahorski, Michael S., Murray, Lyndsay M., Shaheen, Ranad, Perkins, Emma, Dissanayake, Kosala N., Kristaryanto, Yosua, Jones, Ross A., Vogt, Julie, Rivagorda, Manon, Handley, Mark T., Mali, Girish R., Quidwai, Tooba, Soares, Dinesh C., Keighren, Margaret A., McKie, Lisa, Mort, Richard L., Gammoh, Noor, Garcia-Munoz, Amaya, Davey, Tracey, Vermeren, Matthieu, Walsh, Diana, Budd, Peter, Aligianis, Irene A., Faqeih, Eissa, Quigley, Alan J., Jackson, Ian J., Kulathu, Yogesh, Jackson, Mandy, Ribchester, Richard R., von Kriegsheim, Alex, Alkuraya, Fowzan S., Woods, C. Geoffrey, Maher, Eamonn R., Mill, Pleasantine
Publicado 2017