Alkaline Phosphatases: Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes

por Millán, José Luis
Publicado 2006

Alkaline Phosphatase and Hypophosphatasia

por Millán, José Luis, Whyte, Michael P.
Publicado 2015

Assay Format as a Critical Success Factor for Identification of Novel Inhibitor Chemotypes of Tissue-Nonspecific Alkaline Phosphatase from High-Throughput Screening

por Chung, Thomas D.Y., Sergienko, Eduard, Millán, José Luis
Publicado 2010

How To Build a Bone: PHOSPHO1, Biomineralization, and Beyond

por Dillon, Scott, Staines, Katherine A, Millán, José Luis, Farquharson, Colin
Publicado 2019

Vascular calcification is dependent on plasma levels of pyrophosphate

por Lomashvili, Koba A., Narisawa, Sonoko, Millán, Jose Luis, O’Neill, W. Charles
Publicado 2014

Effects of etidronate on the Enpp1(−/−) mouse model of generalized arterial calcification of infancy

por HUESA, CARMEN, STAINES, KATHERINE A, MILLÁN, JOSE LUIS, MacRAE, VICKY E
Publicado 2015

The Appearance and Modulation of Osteocyte Marker Expression during Calcification of Vascular Smooth Muscle Cells

por Zhu, Dongxing, Mackenzie, Neil Charles Wallace, Millán, José Luis, Farquharson, Colin, MacRae, Vicky Elizabeth
Publicado 2011

Regenerative capacity in newts is not altered by repeated regeneration and ageing

por Eguchi, Goro, Eguchi, Yukiko, Nakamura, Kenta, Yadav, Manisha C., Millán, José Luis, Tsonis, Panagiotis A.
Publicado 2011

Exonic splicing signals impose constraints upon the evolution of enzymatic activity

por Falanga, Alessia, Stojanović, Ozren, Kiffer-Moreira, Tina, Pinto, Sofia, Millán, José Luis, Vlahoviček, Kristian, Baralle, Marco
Publicado 2014

Reference point indentation is not indicative of whole mouse bone measures of stress intensity fracture toughness

por Carriero, Alessandra, Bruse, Jan L., Oldknow, Karla J., Millán, José Luis, Farquharson, Colin, Shefelbine, Sandra J.
Publicado 2014

Functional Significance of Calcium Binding to Tissue-Nonspecific Alkaline Phosphatase

por Hoylaerts, Marc F., Van kerckhoven, Soetkin, Kiffer-Moreira, Tina, Sheen, Campbell, Narisawa, Sonoko, Millán, José Luis
Publicado 2015

Transgenic Overexpression of Tissue‐Nonspecific Alkaline Phosphatase (TNAP) in Vascular Endothelium Results in Generalized Arterial Calcification

por Savinov, Alexei Y., Salehi, Maryam, Yadav, Manisha C., Radichev, Ilian, Millán, José Luis, Savinova, Olga V.
Publicado 2015

PAR2 regulates regeneration, transdifferentiation, and death

por Piran, Ron, Lee, Seung-Hee, Kuss, Pia, Hao, Ergeng, Newlin, Robbin, Millán, José Luis, Levine, Fred
Publicado 2016

Chronic Kidney Disease-Induced Arterial Media Calcification in Rats Prevented by Tissue Non-Specific Alkaline Phosphatase Substrate Supplementation Rather Than Inhibition of the En...

por Opdebeeck, Britt, Neven, Ellen, Millán, José Luis, Pinkerton, Anthony B., D’Haese, Patrick C., Verhulst, Anja
Publicado 2021

Prolonged Survival and Phenotypic Correction of Akp2(−/−) Hypophosphatasia Mice by Lentiviral Gene Therapy

por Yamamoto, Seiko, Orimo, Hideo, Matsumoto, Tae, Iijima, Osamu, Narisawa, Sonoko, Maeda, Takahide, Millán, José Luis, Shimada, Takashi
Publicado 2011

Bone Alkaline Phosphatase and Tartrate-Resistant Acid Phosphatase: Potential Co-regulators of Bone Mineralization

por Halling Linder, Cecilia, Ek-Rylander, Barbro, Krumpel, Michael, Norgård, Maria, Narisawa, Sonoko, Millán, José Luis, Andersson, Göran, Magnusson, Per
Publicado 2017

Treatment with bone maturation and average lifespan of HPP model mice by AAV8-mediated neonatal gene therapy via single muscle injection

por Matsumoto, Tae, Miyake, Koichi, Miyake, Noriko, Iijima, Osamu, Adachi, Kumi, Narisawa, Sonoko, Millán, José Luis, Orimo, Hideo, Shimada, Takashi
Publicado 2021

Gene Therapy Using Adeno‐Associated Virus Serotype 8 Encoding TNAP‐D(10) Improves the Skeletal and Dentoalveolar Phenotypes in Alpl (−/−) Mice

por Kinoshita, Yuka, Mohamed, Fatma F, Amadeu de Oliveira, Flavia, Narisawa, Sonoko, Miyake, Koichi, Foster, Brian L, Millán, José Luis
Publicado 2021

Loss of Skeletal Mineralization by the Simultaneous Ablation of PHOSPHO1 and Alkaline Phosphatase Function: A Unified Model of the Mechanisms of Initiation of Skeletal Calcificatio...

por Yadav, Manisha C, Simão, Ana Maria Sper, Narisawa, Sonoko, Huesa, Carmen, McKee, Marc D, Farquharson, Colin, Millán, José Luis
Publicado 2011

Perspective on Dentoalveolar Manifestations Resulting From PHOSPHO1 Loss-of-Function: A Form of Pseudohypophosphatasia?

por Mohamed, Fatma F., Chavez, Michael B., de Oliveira, Flavia Amadeu, Narisawa, Sonoko, Farquharson, Colin, Millán, José Luis, Foster, Brian L.
Publicado 2022