Structural and Chemical Biology Approaches Reveal Isoform-Selective Mechanisms of Ligand Interactions in Mammalian Cryptochromes

by Miller, Simon, Hirota, Tsuyoshi
Published 2022

Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation

by Miller, Simon, Srivastava, Ashutosh, Nagai, Yoshiko, Aikawa, Yoshiki, Tama, Florence, Hirota, Tsuyoshi
Published 2021

A methylbenzimidazole derivative regulates mammalian circadian rhythms by targeting Cryptochrome proteins

by Yagi, Moeri, Miller, Simon, Nagai, Yoshiko, Inuki, Shinsuke, Sato, Ayato, Hirota, Tsuyoshi
Published 2022

Catalog of triply periodic minimal surfaces, equation-based lattice structures, and their homogenized property data

by Fisher, Joseph W., Miller, Simon W., Bartolai, Joseph, Simpson, Timothy W., Yukish, Michael A.
Published 2023

State Accountability for the Good Health of Palestinians Has Failed: What Can the Global Health Community Do Next?

by Alkhaldi, Mohammed, Coghlan, Rachel, Miller, Simon, Basuoni, Aisha Al, Tanous, Osama, Asi, Yara M.
Published 2022

CRY2 isoform selectivity of a circadian clock modulator with antiglioblastoma efficacy

by Miller, Simon, Kesherwani, Manish, Chan, Priscilla, Nagai, Yoshiko, Yagi, Moeri, Cope, Jamie, Tama, Florence, Kay, Steve A., Hirota, Tsuyoshi
Published 2022

Photopharmacological Manipulation of Mammalian CRY1 for Regulation of the Circadian Clock

by Kolarski, Dušan, Miller, Simon, Oshima, Tsuyoshi, Nagai, Yoshiko, Aoki, Yugo, Kobauri, Piermichele, Srivastava, Ashutosh, Sugiyama, Akiko, Amaike, Kazuma, Sato, Ayato, Tama, Florence, Szymanski, Wiktor, Feringa, Ben L., Itami, Kenichiro, Hirota, Tsuyoshi
Published 2021

The p110δ crystal structure uncovers mechanisms for selectivity and potency of novel PI3K inhibitors

by Berndt, Alex, Miller, Simon, Williams, Olusegun, Le, Daniel D., Houseman, Benjamin T., Pacold, Joseph I., Gorrec, Fabrice, Hon, Wai-Ching, Liu, Yi, Rommel, Christian, Gaillard, Pascale, Ruckle, Thomas, Schwarz, Matthias K., Shokat, Kevan M., Shaw, Jeffrey P., Williams, Roger L.
Published 2010