Rational Redesign of a Functional Protein Kinase-Substrate Interaction

por Chen, Catherine, Nimlamool, Wutigri, Miller, Chad J., Lou, Hua Jane, Turk, Benjamin E.
Publicado 2017

Unmasking Determinants of Specificity in the Human Kinome

por Creixell, Pau, Palmeri, Antonio, Miller, Chad J., Lou, Hua Jane, Santini, Cristina C., Nielsen, Morten, Turk, Benjamin E., Linding, Rune
Publicado 2015

Ancestral resurrection reveals evolutionary mechanisms of kinase plasticity

por Howard, Conor J, Hanson-Smith, Victor, Kennedy, Kristopher J, Miller, Chad J, Lou, Hua Jane, Johnson, Alexander D, Turk, Benjamin E, Holt, Liam J
Publicado 2014

Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs

por van de Kooij, Bert, Creixell, Pau, van Vlimmeren, Anne, Joughin, Brian A, Miller, Chad J, Haider, Nasir, Simpson, Craig D, Linding, Rune, Stambolic, Vuk, Turk, Benjamin E, Yaffe, Michael B
Publicado 2019

Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output

por Miller, Chad J., Lou, Hua Jane, Simpson, Craig, van de Kooij, Bert, Ha, Byung Hak, Fisher, Oriana S., Pirman, Natasha L., Boggon, Titus J., Rinehart, Jesse, Yaffe, Michael B., Linding, Rune, Turk, Benjamin E.
Publicado 2019

Computational design of a synthetic PD-1 agonist

por Bryan, Cassie M., Rocklin, Gabriel J., Bick, Matthew J., Ford, Alex, Majri-Morrison, Sonia, Kroll, Ashley V., Miller, Chad J., Carter, Lauren, Goreshnik, Inna, Kang, Alex, DiMaio, Frank, Tarbell, Kristin V., Baker, David
Publicado 2021

Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling

por Creixell, Pau, Schoof, Erwin M., Simpson, Craig D., Longden, James, Miller, Chad J., Lou, Hua Jane, Perryman, Lara, Cox, Thomas R., Zivanovic, Nevena, Palmeri, Antonio, Wesolowska-Andersen, Agata, Helmer-Citterich, Manuela, Ferkinghoff-Borg, Jesper, Itamochi, Hiroaki, Bodenmiller, Bernd, Erler, Janine T., Turk, Benjamin E., Linding, Rune
Publicado 2015