Poor communication between ER and mitochondria: a signature of ALS/FTD?

por Miller, Christopher C.J., Gomez-Suaga, Patricia
Publicado 2023

ER-mitochondria signaling regulates autophagy

por Gomez-Suaga, Patricia, Paillusson, Sebastien, Miller, Christopher C. J.
Publicado 2017

The Importance of Tau Phosphorylation for Neurodegenerative Diseases

por Noble, Wendy, Hanger, Diane P., Miller, Christopher C. J., Lovestone, Simon
Publicado 2013

Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production

por Vagnoni, Alessio, Perkinton, Michael S., Gray, Emma H., Francis, Paul T., Noble, Wendy, Miller, Christopher C.J.
Publicado 2012

The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy

por Gomez-Suaga, Patricia, Paillusson, Sebastien, Stoica, Radu, Noble, Wendy, Hanger, Diane P., Miller, Christopher C.J.
Publicado 2017

Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production

por Vagnoni, Alessio, Glennon, Elizabeth B.C., Perkinton, Michael S., Gray, Emma H., Noble, Wendy, Miller, Christopher C.J.
Publicado 2013

Dissociation of Axonal Neurofilament Content from Its Transport Rate

por Yuan, Aidong, Hassinger, Linda, Rao, Mala V., Julien, Jean-Pierre, Miller, Christopher C. J., Nixon, Ralph A.
Publicado 2015

Targeting ER-Mitochondria Signaling as a Therapeutic Target for Frontotemporal Dementia and Related Amyotrophic Lateral Sclerosis

por Martín-Guerrero, Sandra M., Markovinovic, Andrea, Mórotz, Gábor M., Salam, Shaakir, Noble, Wendy, Miller, Christopher C. J.
Publicado 2022

Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria

por Mórotz, Gábor M., De Vos, Kurt J., Vagnoni, Alessio, Ackerley, Steven, Shaw, Christopher E., Miller, Christopher C.J.
Publicado 2012

There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases

por Paillusson, Sebastien, Stoica, Radu, Gomez-Suaga, Patricia, Lau, Dawn H.W., Mueller, Sarah, Miller, Tanya, Miller, Christopher C.J.
Publicado 2016

Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments

por Ackerley, Steven, Thornhill, Paul, Grierson, Andrew J., Brownlees, Janet, Anderton, Brian H., Leigh, P. Nigel, Shaw, Christopher E., Miller, Christopher C.J.
Publicado 2003

Glutamate Slows Axonal Transport of Neurofilaments in Transfected Neurons

por Ackerley, Steven, Grierson, Andrew J., Brownlees, Janet, Thornhill, Paul, Anderton, Brian H., Leigh, P. Nigel, Shaw, Christopher E., Miller, Christopher C.J.
Publicado 2000

Lemur tyrosine kinase-2 signalling regulates kinesin light chain-2 phosphorylation and binding of Smad2 cargo

por Manser, Catherine, Guillot, Florence, Vagnoni, Alessio, Davies, Jennifer, Lau, Kwok-Fai, McLoughlin, Declan M., De Vos, Kurt J., Miller, Christopher C.J.
Publicado 2011

α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca(2+) homeostasis and mitochondrial ATP production

por Paillusson, Sébastien, Gomez-Suaga, Patricia, Stoica, Radu, Little, Daniel, Gissen, Paul, Devine, Michael J., Noble, Wendy, Hanger, Diane P., Miller, Christopher C. J.
Publicado 2017

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

por De Vos, Kurt J., Mórotz, Gábor M., Stoica, Radu, Tudor, Elizabeth L., Lau, Kwok-Fai, Ackerley, Steven, Warley, Alice, Shaw, Christopher E., Miller, Christopher C.J.
Publicado 2012

Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations

por Godena, Vinay K., Brookes-Hocking, Nicholas, Moller, Annekathrin, Shaw, Gary, Oswald, Matthew, Sancho, Rosa M., Miller, Christopher C. J., Whitworth, Alexander J., De Vos, Kurt J.
Publicado 2014

LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer’s disease brains

por Mórotz, Gábor M., Glennon, Elizabeth B., Gomez-Suaga, Patricia, Lau, Dawn H. W., Robinson, Eleanor D., Sedlák, Éva, Vagnoni, Alessio, Noble, Wendy, Miller, Christopher C. J.
Publicado 2019

Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer’s disease and regulates axonal transport and processing of the amyloid precursor protein

por Mórotz, Gábor M., Glennon, Elizabeth B., Greig, Jenny, Lau, Dawn H. W., Bhembre, Nishita, Mattedi, Francesca, Muschalik, Nadine, Noble, Wendy, Vagnoni, Alessio, Miller, Christopher C. J.
Publicado 2019

Disruption of endoplasmic reticulum-mitochondria tethering proteins in post-mortem Alzheimer's disease brain

por Lau, Dawn H.W., Paillusson, Sebastien, Hartopp, Naomi, Rupawala, Huzefa, Mórotz, Gábor M., Gomez-Suaga, Patricia, Greig, Jenny, Troakes, Claire, Noble, Wendy, Miller, Christopher C.J.
Publicado 2020

Phosphorylation of FE65 Ser(610) by serum- and glucocorticoid-induced kinase 1 modulates Alzheimer's disease amyloid precursor protein processing

por Chow, Wan Ning Vanessa, Ngo, Jacky Chi Ki, Li, Wen, Chen, Yu Wai, Tam, Ka Ming Vincent, Chan, Ho Yin Edwin, Miller, Christopher C.J., Lau, Kwok-Fai
Publicado 2015