Genome-Wide Association Studies Candidate Gene to Dual Modifier of Nonalcoholic Steatohepatitis and Atherosclerosis

por Miller, Clint L., Leeper, Nicholas J.
Publicado 2016

GWAS Reveal Targets in Vessel Wall Pathways to Treat Coronary Artery Disease

por Turner, Adam W., Wong, Doris, Dreisbach, Caitlin N., Miller, Clint L.
Publicado 2018

Multi-Omics Approaches to Study Long Non-coding RNA Function in Atherosclerosis

por Turner, Adam W., Wong, Doris, Khan, Mohammad Daud, Dreisbach, Caitlin N., Palmore, Meredith, Miller, Clint L.
Publicado 2019

TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression

por Zhao, Quanyi, Wirka, Robert, Nguyen, Trieu, Nagao, Manabu, Cheng, Paul, Miller, Clint L., Kim, Juyong Brian, Pjanic, Milos, Quertermous, Thomas
Publicado 2019

Gene-repressing epigenetic reader EED unexpectedly enhances cyclinD1 gene activation

por Zhang, Mengxue, Li, Jing, Wang, Qingwei, Urabe, Go, Tang, Runze, Huang, Yitao, Mosquera, Jose Verdezoto, Kent, K. Craig, Wang, Bowen, Miller, Clint L., Guo, Lian-Wang
Publicado 2023

Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk

por Iyer, Dharini, Zhao, Quanyi, Wirka, Robert, Naravane, Ameay, Nguyen, Trieu, Liu, Boxiang, Nagao, Manabu, Cheng, Paul, Miller, Clint L., Kim, Juyong Brian, Pjanic, Milos, Quertermous, Thomas
Publicado 2018

TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells

por Kim, Juyong Brian, Pjanic, Milos, Nguyen, Trieu, Miller, Clint L., Iyer, Dharini, Liu, Boxiang, Wang, Ting, Sazonova, Olga, Carcamo-Orive, Ivan, Matic, Ljubica Perisic, Maegdefessel, Lars, Hedin, Ulf, Quertermous, Thomas
Publicado 2017

An automatic entropy method to efficiently mask histology whole-slide images

por Song, Yipei, Cisternino, Francesco, Mekke, Joost M., de Borst, Gert J., de Kleijn, Dominique P. V., Pasterkamp, Gerard, Vink, Aryan, Glastonbury, Craig A., van der Laan, Sander W., Miller, Clint L.
Publicado 2023

PlaqView 2.0: A comprehensive web portal for cardiovascular single-cell genomics

por Ma, Wei Feng, Turner, Adam W., Gancayco, Christina, Wong, Doris, Song, Yipei, Mosquera, Jose Verdezoto, Auguste, Gaëlle, Hodonsky, Chani J., Prabhakar, Ajay, Ekiz, H. Atakan, van der Laan, Sander W., Miller, Clint L.
Publicado 2022

Coronary Heart Disease-Associated Variation in TCF21 Disrupts a miR-224 Binding Site and miRNA-Mediated Regulation

por Miller, Clint L., Haas, Ulrike, Diaz, Roxanne, Leeper, Nicholas J., Kundu, Ramendra K., Patlolla, Bhagat, Assimes, Themistocles L., Kaiser, Frank J., Perisic, Ljubica, Hedin, Ulf, Maegdefessel, Lars, Schunkert, Heribert, Erdmann, Jeanette, Quertermous, Thomas, Sczakiel, Georg
Publicado 2014

Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of TCF21 Expression at the 6q23.2 Coronary Heart Disease Locus

por Miller, Clint L., Anderson, D. Ryan, Kundu, Ramendra K., Raiesdana, Azad, Nürnberg, Sylvia T., Diaz, Roxanne, Cheng, Karen, Leeper, Nicholas J., Chen, Chung-Hsing, Chang, I-Shou, Schadt, Eric E., Hsiung, Chao Agnes, Assimes, Themistocles L., Quertermous, Thomas
Publicado 2013

Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence Data

por Dewey, Frederick E., Grove, Megan E., Priest, James R., Waggott, Daryl, Batra, Prag, Miller, Clint L., Wheeler, Matthew, Zia, Amin, Pan, Cuiping, Karzcewski, Konrad J., Miyake, Christina, Whirl-Carrillo, Michelle, Klein, Teri E., Datta, Somalee, Altman, Russ B., Snyder, Michael, Quertermous, Thomas, Ashley, Euan A.
Publicado 2015

Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus

por Nanda, Vivek, Wang, Ting, Pjanic, Milos, Liu, Boxiang, Nguyen, Trieu, Matic, Ljubica Perisic, Hedin, Ulf, Koplev, Simon, Ma, Lijiang, Franzén, Oscar, Ruusalepp, Arno, Schadt, Eric E., Björkegren, Johan L. M., Montgomery, Stephen B., Snyder, Michael P., Quertermous, Thomas, Leeper, Nicholas J., Miller, Clint L.
Publicado 2018

Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer disease

por Aguilar-Pineda, Jorge A., Vera-Lopez, Karin J., Shrivastava, Pallavi, Chávez-Fumagalli, Miguel A., Nieto-Montesinos, Rita, Alvarez-Fernandez, Karla L., Goyzueta Mamani, Luis D., Davila Del-Carpio, Gonzalo, Gomez-Valdez, Badhin, Miller, Clint L., Malhotra, Rajeev, Lindsay, Mark E., Lino Cardenas, Christian L.
Publicado 2021

The accumulation of erythrocytes quantified and visualized by Glycophorin C in carotid atherosclerotic plaque reflects intraplaque hemorrhage and pre-procedural neurological sympt...

por Mekke, Joost M., Sakkers, Tim R., Verwer, Maarten C., van den Dungen, Noortje A. M., Song, Yipei, Miller, Clint L., Finn, Aloke V., Pasterkamp, Gerard, Mokry, Michal, den Ruijter, Hester M., Vink, Aryan, de Kleijn, Dominique P. V., de Borst, Gert J., Haitjema, Saskia, van der Laan, Sander W.
Publicado 2023

Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap

por Nurnberg, Sylvia T., Cheng, Karen, Raiesdana, Azad, Kundu, Ramendra, Miller, Clint L., Kim, Juyong B., Arora, Komal, Carcamo-Oribe, Ivan, Xiong, Yiqin, Tellakula, Nikhil, Nanda, Vivek, Murthy, Nikitha, Boisvert, William A., Hedin, Ulf, Perisic, Ljubica, Aldi, Silvia, Maegdefessel, Lars, Pjanic, Milos, Owens, Gary K., Tallquist, Michelle D., Quertermous, Thomas
Publicado 2015

Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci

por Miller, Clint L., Pjanic, Milos, Wang, Ting, Nguyen, Trieu, Cohain, Ariella, Lee, Jonathan D., Perisic, Ljubica, Hedin, Ulf, Kundu, Ramendra K., Majmudar, Deshna, Kim, Juyong B., Wang, Oliver, Betsholtz, Christer, Ruusalepp, Arno, Franzén, Oscar, Assimes, Themistocles L., Montgomery, Stephen B., Schadt, Eric E., Björkegren, Johan L.M., Quertermous, Thomas
Publicado 2016

The HDAC9-associated risk locus promotes coronary artery disease by governing TWIST1

por Ma, Lijiang, Bryce, Nicole S., Turner, Adam W., Di Narzo, Antonio F., Rahman, Karishma, Xu, Yang, Ermel, Raili, Sukhavasi, Katyayani, d’Escamard, Valentina, Chandel, Nirupama, V’Gangula, Bhargavi, Wolhuter, Kathryn, Kadian-Dodov, Daniella, Franzen, Oscar, Ruusalepp, Arno, Hao, Ke, Miller, Clint L., Björkegren, Johan L. M., Kovacic, Jason C.
Publicado 2022

Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis

por Wirka, Robert C., Wagh, Dhananjay, Paik, David T., Pjanic, Milos, Nguyen, Trieu, Miller, Clint L., Kundu, Ramen, Nagao, Manabu, Coller, John, Koyano, Tiffany K., Fong, Robyn, Woo, Y. Joseph, Liu, Boxiang, Montgomery, Stephen B., Wu, Joseph C., Zhu, Kuixi, Chang, Rui, Alamprese, Melissa, Tallquist, Michelle D., Kim, Juyong B., Quertermous, Thomas
Publicado 2019

Treatment of calcific arterial disease via enhancement of autophagy using GSK343

por Lino Cardenas, Christian L., Jiang, Wanlin, Kajuluri, Lova P., Singh, Kuldeep, Ostrom, Katrina, Li, Rebecca, Cherbonneau, Francois, Boerboom, Sophie, Birchenough, Claire, Roh, Kangsan, Chou, Elizabeth L., Shahrooz, Zarbafian, Nicholson, Christopher, Johnson, Adam L., Lee, Sujin, Ichinose, Fumito, Bloch, Donald B., Nigwekar, Sagar, Ellinor, Patrick T., Musolino, Patricia, Lindsay, Mark E., Dou, Zhixun, Miller, Clint L., Malhotra, Rajeev
Publicado 2023