Selective inhibition of CDK4/6: A safe and effective strategy for developing anticancer drugs

por Yuan, Kai, Wang, Xiao, Dong, Haojie, Min, Wenjian, Hao, Haiping, Yang, Peng
Publicado 2021

Development and clinical advancement of small molecules for ex vivo expansion of hematopoietic stem cell

por Li, Jiaxing, Wang, Xiao, Ding, Jiayu, Zhu, Yasheng, Min, Wenjian, Kuang, Wenbing, Yuan, Kai, Sun, Chengliang, Yang, Peng
Publicado 2022

Tubeimoside-1 induces TFEB-dependent lysosomal degradation of PD-L1 and promotes antitumor immunity by targeting mTOR

por Liu, Xiaojia, Yin, Mingxiao, Dong, Jingwen, Mao, Genxiang, Min, Wenjian, Kuang, Zean, Yang, Peng, Liu, Lu, Zhang, Na, Deng, Hongbin
Publicado 2021

Limonin, a natural ERK2 agonist, protects against ischemic acute kidney injury

por Zhou, Xianke, Xiang, Yadie, Li, Dier, Zhong, Menghua, Hong, Xue, Gui, Yuan, Min, Wenjian, Chen, Yudan, Zeng, Xi, Zhu, Haili, Liu, Youhua, Liu, Shijia, Yang, Peng, Hou, Fanfan, Zhou, Dong, Fu, Haiyan
Publicado 2023

Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 with a highly selective inhibitor for the treatment of prostate cancer

por Yuan, Kai, Li, Zhaoxing, Kuang, Wenbin, Wang, Xiao, Ji, Minghui, Chen, Weijiao, Ding, Jiayu, Li, Jiaxing, Min, Wenjian, Sun, Chengliang, Ye, Xiuquan, Lu, Meiling, Wang, Liping, Ge, Haixia, Jiang, Yuzhang, Hao, Haiping, Xiao, Yibei, Yang, Peng
Publicado 2022

Novel phthalimides regulating PD-1/PD-L1 interaction as potential immunotherapy agents

por Sun, Chengliang, Cheng, Yao, Liu, Xiaojia, Wang, Gefei, Min, Wenjian, Wang, Xiao, Yuan, Kai, Hou, Yi, Li, Jiaxing, Zhang, Haolin, Dong, Haojie, Wang, Liping, Lou, Chenguang, Sun, Yanze, Yu, Xinmiao, Deng, Hongbin, Xiao, Yibei, Yang, Peng
Publicado 2022

B7-1 mediates podocyte injury and glomerulosclerosis through communication with Hsp90ab1-LRP5-β-catenin pathway

por Li, Jiemei, Niu, Jing, Min, Wenjian, Ai, Jun, Lin, Xu, Miao, Jinhua, Zhou, Shan, Liang, Ye, Chen, Shuangqin, Ren, Qian, Shen, Kunyu, Wu, Qinyu, Li, Xiaolong, Shen, Weiwei, Hou, Fan Fan, Liu, Youhua, Yang, Peng, Zhou, Lili
Publicado 2022

A new LKB1 activator, piericidin analogue S14, retards renal fibrosis through promoting autophagy and mitochondrial homeostasis in renal tubular epithelial cells

por Liu, Canzhen, Wang, Xiaoxu, Wang, Xiaonan, Zhang, Yunfang, Min, Wenjian, Yu, Ping, Miao, Jinhua, Shen, Weiwei, Chen, Shuangqin, Zhou, Shan, Li, Xiaolong, Meng, Ping, Wu, Qinyu, Hou, Fan Fan, Liu, Youhua, Yang, Peng, Wang, Cheng, Lin, Xu, Tang, Lan, Zhou, Xuefeng, Zhou, Lili
Publicado 2022