Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer

por Leonetti, Alessandro, Sharma, Sugandhi, Minari, Roberta, Perego, Paola, Giovannetti, Elisa, Tiseo, Marcello
Publicado 2019

Role of ctDNA for the detection of minimal residual disease in resected non-small cell lung cancer: a systematic review

por Verzè, Michela, Pluchino, Monica, Leonetti, Alessandro, Corianò, Matilde, Bonatti, Francesco, Armillotta, Maria P., Perrone, Fabiana, Casali, Miriam, Minari, Roberta, Tiseo, Marcello
Publicado 2022

Small Cell Lung Cancer Transformation as a Resistance Mechanism to Osimertinib in Epidermal Growth Factor Receptor-Mutated Lung Adenocarcinoma: Case Report and Literature Review

por Leonetti, Alessandro, Minari, Roberta, Mazzaschi, Giulia, Gnetti, Letizia, La Monica, Silvia, Alfieri, Roberta, Campanini, Nicoletta, Verzè, Michela, Olivani, Andrea, Ventura, Luigi, Tiseo, Marcello
Publicado 2021

It Takes Two to Tango: Potential Prognostic Impact of Circulating TGF-Beta and PD-L1 in Pancreatic Cancer

por Garajová, Ingrid, Cavazzoni, Andrea, Verze, Michela, Minari, Roberta, Pedrazzi, Giuseppe, Balsano, Rita, Gelsomino, Fabio, Valle, Raffaele Dalla, Digiacomo, Graziana, Giovannetti, Elisa, Leonardi, Francesco
Publicado 2022

Dynamic Evaluation of Circulating miRNA Profile in EGFR-Mutated NSCLC Patients Treated with EGFR-TKIs

por Leonetti, Alessandro, Capula, Mjriam, Minari, Roberta, Mazzaschi, Giulia, Gregori, Alessandro, El Hassouni, Btissame, Papini, Filippo, Bordi, Paola, Verzè, Michela, Avan, Amir, Tiseo, Marcello, Giovannetti, Elisa
Publicado 2021

Emergence of a HER2-amplified clone during disease progression in an ALK-rearranged NSCLC patient treated with ALK-inhibitors: a case report

por Minari, Roberta, Gnetti, Letizia, Lagrasta, Costanza Annamaria, Squadrilli, Anna, Bordi, Paola, Azzoni, Cinzia, Bottarelli, Lorena, Cosenza, Agnese, Ferri, Leonarda, Caruso, Giuseppe, Silini, Enrico Maria, Tiseo, Marcello
Publicado 2020

The amount of activating EGFR mutations in circulating cell-free DNA is a marker to monitor osimertinib response

por Del Re, Marzia, Bordi, Paola, Rofi, Eleonora, Restante, Giuliana, Valleggi, Simona, Minari, Roberta, Crucitta, Stefania, Arrigoni, Elena, Chella, Antonio, Morganti, Riccardo, Tiseo, Marcello, Petrini, Iacopo, Danesi, Romano
Publicado 2018

Intrinsic Resistance to Osimertinib in EGFR Mutated NSCLC Cell Lines Induced by Alteration in Cell-Cycle Regulators

por Volta, Francesco, La Monica, Silvia, Leonetti, Alessandro, Gnetti, Letizia, Bonelli, Mara, Cavazzoni, Andrea, Fumarola, Claudia, Galetti, Maricla, Eltayeb, Kamal, Minari, Roberta, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
Publicado 2023

Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines

por La Monica, Silvia, Cretella, Daniele, Bonelli, Mara, Fumarola, Claudia, Cavazzoni, Andrea, Digiacomo, Graziana, Flammini, Lisa, Barocelli, Elisabetta, Minari, Roberta, Naldi, Nadia, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
Publicado 2017

Efficacy of the CDK4/6 Dual Inhibitor Abemaciclib in EGFR-Mutated NSCLC Cell Lines with Different Resistance Mechanisms to Osimertinib

por La Monica, Silvia, Fumarola, Claudia, Cretella, Daniele, Bonelli, Mara, Minari, Roberta, Cavazzoni, Andrea, Digiacomo, Graziana, Galetti, Maricla, Volta, Francesco, Mancini, Maicol, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
Publicado 2020

Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell L...

por Fumarola, Claudia, Bozza, Nicole, Castelli, Riccardo, Ferlenghi, Francesca, Marseglia, Giuseppe, Lodola, Alessio, Bonelli, Mara, La Monica, Silvia, Cretella, Daniele, Alfieri, Roberta, Minari, Roberta, Galetti, Maricla, Tiseo, Marcello, Ardizzoni, Andrea, Mor, Marco, Petronini, Pier Giorgio
Publicado 2019

Dataset on the identification of a prognostic radio-immune signature in surgically resected Non Small Cell Lung Cancer

por Mazzaschi, Giulia, Milanese, Gianluca, Pagano, Paolo, Madeddu, Denise, Gnetti, Letizia, Trentini, Francesca, Falco, Angela, Frati, Caterina, Lorusso, Bruno, Lagrasta, Costanza, Minari, Roberta, Ampollini, Luca, Silva, Mario, Sverzellati, Nicola, Quaini, Federico, Roti, Giovanni, Tiseo, Marcello
Publicado 2020

Monitoring cfDNA in Plasma and in Other Liquid Biopsies of Advanced EGFR Mutated NSCLC Patients: A Pilot Study and a Review of the Literature

por Verzè, Michela, Minari, Roberta, Gnetti, Letizia, Bordi, Paola, Leonetti, Alessandro, Cosenza, Agnese, Ferri, Leonarda, Majori, Maria, De Filippo, Massimo, Buti, Sebastiano, Gasparro, Donatello, Nizzoli, Rita, Azzoni, Cinzia, Bottarelli, Lorena, Squadrilli, Anna, Mozzoni, Paola, Tiseo, Marcello
Publicado 2021

Third generation EGFR inhibitor osimertinib combined with pemetrexed or cisplatin exerts long-lasting anti-tumor effect in EGFR-mutated pre-clinical models of NSCLC

por La Monica, Silvia, Minari, Roberta, Cretella, Daniele, Flammini, Lisa, Fumarola, Claudia, Bonelli, Mara, Cavazzoni, Andrea, Digiacomo, Graziana, Galetti, Maricla, Madeddu, Denise, Falco, Angela, Lagrasta, Costanza Annamaria, Squadrilli, Anna, Barocelli, Elisabetta, Romanel, Alessandro, Quaini, Federico, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
Publicado 2019

YES1 and MYC Amplifications as Synergistic Resistance Mechanisms to Different Generation ALK Tyrosine Kinase Inhibitors in Advanced NSCLC: Brief Report of Clinical and Preclinical...

por Minari, Roberta, Valentini, Samuel, Madeddu, Denise, Cavazzoni, Andrea, La Monica, Silvia, Lagrasta, Costanza Anna Maria, Bertorelli, Roberto, De Sanctis, Veronica, Fassan, Paola, Azzoni, Cinzia, Bottarelli, Lorena, Frati, Caterina, Gnetti, Letizia, Facchinetti, Francesco, Petronini, Pier Giorgio, Alfieri, Roberta, Romanel, Alessandro, Tiseo, Marcello
Publicado 2022

Multicenter Observational Study on Metastatic Non-Small Cell Lung Cancer Harboring BRAF Mutations: Focus on Clinical Characteristics and Treatment Outcome of V600E and Non-V600E Su...

por Perrone, Fabiana, Mazzaschi, Giulia, Minari, Roberta, Verzè, Michela, Azzoni, Cinzia, Bottarelli, Lorena, Nizzoli, Rita, Pluchino, Monica, Altimari, Annalisa, Gruppioni, Elisa, Sperandi, Francesca, Andrini, Elisa, Guaitoli, Giorgia, Bertolini, Federica, Barbieri, Fausto, Bettelli, Stefania, Longo, Lucia, Pagano, Maria, Bonelli, Candida, Tagliavini, Elena, Nicoli, Davide, Ubiali, Alessandro, Zangrandi, Adriano, Trubini, Serena, Proietto, Manuela, Gnetti, Letizia, Tiseo, Marcello
Publicado 2022