Exploiting an Interleukin-15 Heterodimeric Agonist (N803) for Effective Immunotherapy of Solid Malignancies

por Lui, Grace, Minnar, Christine M., Soon-Shiong, Patrick, Schlom, Jeffrey, Gameiro, Sofia R.
Publicado 2023

Analysis of the tumor microenvironment and anti-tumor efficacy of subcutaneous vs systemic delivery of the bifunctional agent bintrafusp alfa

por Ozawa, Yohei, Hicks, Kristin C., Minnar, Christine M., Knudson, Karin M., Schlom, Jeffrey, Gameiro, Sofia R.
Publicado 2021

Tumor-targeted interleukin-12 synergizes with entinostat to overcome PD-1/PD-L1 blockade-resistant tumors harboring MHC-I and APM deficiencies

por Minnar, Christine M, Chariou, Paul L, Horn, Lucas A, Hicks, Kristin C, Palena, Claudia, Schlom, Jeffrey, Gameiro, Sofia R
Publicado 2022

Tumour-targeted interleukin-12 and entinostat combination therapy improves cancer survival by reprogramming the tumour immune cell landscape

por Hicks, Kristin C., Chariou, Paul L., Ozawa, Yohei, Minnar, Christine M., Knudson, Karin M., Meyer, Thomas J., Bian, Jing, Cam, Margaret, Schlom, Jeffrey, Gameiro, Sofia R.
Publicado 2021

Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy

por Sckisel, Gail D., Mirsoian, Annie, Minnar, Christine M., Crittenden, Marka, Curti, Brendan, Chen, Jane Q., Blazar, Bruce R., Borowsky, Alexander D., Monjazeb, Arta M., Murphy, William J.
Publicado 2017

Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade

por Wang, Ziming, Aguilar, Ethan G., Luna, Jesus I., Dunai, Cordelia, Khuat, Lam T., Le, Catherine T., Mirsoian, Annie, Minnar, Christine M., Stoffel, Kevin M., Sturgill, Ian R., Grossenbacher, Steven K., Withers, Sita S., Rebhun, Robert B., Hartigan-O’Connor, Dennis J., Méndez-Lagares, Gema, Tarantal, Alice F., Isseroff, R. Rivkah, Griffith, Thomas S., Schalper, Kurt A., Merleev, Alexander, Saha, Asim, Maverakis, Emanual, Kelly, Karen, Aljumaily, Raid, Ibrahimi, Sami, Mukherjee, Sarbajit, Machiorlatti, Michael, Vesely, Sara K., Longo, Dan L., Blazar, Bruce R., Canter, Robert J., Murphy, William J., Monjazeb, Arta M.
Publicado 2018