Novel Approaches and Challenges of Discovery of Exosite Modulators of a Disintegrin and Metalloprotease 10

por Minond, Dmitriy
Publicado 2020

Tyrosine O-GalNAc Alters the Conformation and Proteolytic Susceptibility of APP Model Glycopeptides

por Singh, YashoNandini, Ormaza, David, Massetti, Alessandra, Minond, Dmitriy, Cudic, Maré
Publicado 2021

In Silico and Experimental ADAM17 Kinetic Modeling as Basis for Future Screening System for Modulators

por Bienstein, Marian, Minond, Dmitriy, Schwaneberg, Ulrich, Davari, Mehdi D., Yildiz, Daniela
Publicado 2022

Droplet Microfluidics-Based Fabrication of Monodisperse Poly(ethylene glycol)-Fibrinogen Breast Cancer Microspheres for Automated Drug Screening Applications

por Seeto, Wen J., Tian, Yuan, Pradhan, Shantanu, Minond, Dmitriy, Lipke, Elizabeth A.
Publicado 2022

In Vivo Acute Toxicity Studies of Novel Anti-Melanoma Compounds Downregulators of hnRNPH1/H2

por Velayutham, Sadeeshkumar, Seal, Trisha, Danthurthy, Samaya, Zaias, Julia, Smalley, Keiran S. M., Minond, Dmitriy
Publicado 2023

Mucin-Type O-Glycosylation Proximal to β-Secretase Cleavage Site Affects APP Processing and Aggregation Fate

por Singh, YashoNandini, Regmi, Deepika, Ormaza, David, Ayyalasomayajula, Ramya, Vela, Nancy, Mundim, Gustavo, Du, Deguo, Minond, Dmitriy, Cudic, Maré
Publicado 2022

A Novel Probe for Spliceosomal Proteins that Induces Autophagy and Death of Melanoma Cells Reveals New Targets for Melanoma Drug Discovery

por Palrasu, Manikandan, Knapinska, Anna M., Diez, Juan, Smith, Lyndsay, LaVoi, Travis, Giulianotti, Marc, Houghten, Richard A., Fields, Gregg B., Minond, Dmitriy
Publicado 2019

Discovery and Optimization of Selective Inhibitors of Meprin α (Part I)

por Hou, Shurong, Diez, Juan, Wang, Chao, Becker-Pauly, Christoph, Fields, Gregg B., Bannister, Thomas, Spicer, Timothy P., Scampavia, Louis D., Minond, Dmitriy
Publicado 2021

Discovery and Optimization of Selective Inhibitors of Meprin α (Part II)

por Wang, Chao, Diez, Juan, Park, Hajeung, Becker-Pauly, Christoph, Fields, Gregg B., Spicer, Timothy P., Scampavia, Louis D., Minond, Dmitriy, Bannister, Thomas D.
Publicado 2021

Novel Pyrrolidine Diketopiperazines Selectively Inhibit Melanoma Cells via Induction of Late-Onset Apoptosis

por Onwuha-Ekpete, Lillian, Tack, Lisa, Knapinska, Anna, Smith, Lyndsay, Kaushik, Gaurav, LaVoi, Travis, Giulianotti, Marc, Houghten, Richard A., Fields, Gregg B., Minond, Dmitriy
Publicado 2014

Characterization of Selective Exosite-Binding Inhibitors of Matrix Metalloproteinase 13 That Prevent Articular Cartilage Degradation in Vitro

por Spicer, Timothy P., Jiang, Jianwen, Taylor, Alexander B., Choi, Jun Yong, Hart, P. John, Roush, William R., Fields, Gregg B., Hodder, Peter S., Minond, Dmitriy
Publicado 2014

Novel Anti-Melanoma Compounds Are Efficacious in A375 Cell Line Xenograft Melanoma Model in Nude Mice

por Velayutham, Sadeeshkumar, Seerattan, Ryan, Sultan, Maab, Seal, Trisha, Danthurthy, Samaya, Chinnappan, Baskaran, Landi, Jessica, Pearl, Kaitlyn, Singh, Aveta, Smalley, Keiran S. M., Zaias, Julia, Choi, Jun Yong, Minond, Dmitriy
Publicado 2023

Discovery of an enzyme and substrate selective inhibitor of ADAM10 using an exosite-binding glycosylated substrate

por Madoux, Franck, Dreymuller, Daniela, Pettiloud, Jean-Phillipe, Santos, Radleigh, Becker-Pauly, Christoph, Ludwig, Andreas, Fields, Gregg B., Bannister, Thomas, Spicer, Timothy P., Cudic, Mare, Scampavia, Louis D., Minond, Dmitriy
Publicado 2016

Soluble Sema4D cleaved from osteoclast precursors by TACE suppresses osteoblastogenesis

por Ishii, Takenobu, Ruiz‐Torruella, Montserrat, Kim, Jae Young, Kanzaki, Hiroyuki, Albassam, Abdullah, Wisitrasameewong, Wichaya, Shindo, Satoru, Pierrelus, Roodelyne, Heidari, Alireza, Kandalam, Umadevi, Nakamura, Shin, Movila, Alexandru, Minond, Dmitriy, Kawai, Toshihisa
Publicado 2023

Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide

por Schaal, Justin B., Tran, Dat Q., Subramanian, Akshay, Patel, Reshma, Laragione, Teresina, Roberts, Kevin D., Trinh, Katie, Tongaonkar, Prasad, Tran, Patti A., Minond, Dmitriy, Fields, Gregg B., Beringer, Paul, Ouellette, André J., Gulko, Percio S., Selsted, Michael E.
Publicado 2017