Disruption of the IS6-AID Linker Affects Voltage-gated Calcium Channel Inactivation and Facilitation

por Findeisen, Felix, Minor, Daniel L.
Publicado 2009

Disruption of the IS6-AID linker affects voltage-gated calcium channel inactivation and facilitation

por Findeisen, Felix, Minor, Daniel L.
Publicado 2010

Metabolic and thermal stimuli control K(2P)2.1 (TREK-1) through modular sensory and gating domains

por Bagriantsev, Sviatoslav N, Clark, Kimberly A, Minor, Daniel L
Publicado 2012

Structural Insights into the Mechanisms and Pharmacology of K(2P) Potassium Channels

por Natale, Andrew M., Deal, Parker E., Minor, Daniel L.
Publicado 2021

Multiple modalities converge on a common gate to control K(2P) channel function

por Bagriantsev, Sviatoslav N, Peyronnet, Rémi, Clark, Kimberly A, Honoré, Eric, Minor, Daniel L
Publicado 2011

Structure of the saxiphilin:saxitoxin (STX) complex reveals a convergent molecular recognition strategy for paralytic toxins

por Yen, Tien-Jui, Lolicato, Marco, Thomas-Tran, Rhiannon, Du Bois, J., Minor, Daniel L.
Publicado 2019

Electro-chemical coupling in the voltage-dependent phosphatase Ci-VSP

por Kohout, Susy C., Bell, Sarah C., Liu, Lijun, Xu, Qiang, Minor, Daniel L., Isacoff, Ehud Y.
Publicado 2010

Tethered Protein Display Identifies a Novel Kir3.2 (GIRK2) Regulator from Protein Scaffold Libraries

por Bagriantsev, Sviatoslav N., Chatelain, Franck C., Clark, Kimberly A., Alagem, Noga, Reuveny, Eitan, Minor, Daniel L.
Publicado 2014

K(2P)2.1(TREK-1):activator complexes reveal a cryptic selectivity filter binding site

por Lolicato, Marco, Arrigoni, Cristina, Mori, Takahiro, Sekioka, Yoko, Bryant, Clifford, Clark, Kimberly A., Minor, Daniel L.
Publicado 2017

Protein and Chemical Determinants of BL-1249 Action and Selectivity for K(2P) Channels

por Pope, Lianne, Arrigoni, Cristina, Lou, Hubing, Bryant, Clifford, Gallardo-Godoy, Alejandra, Renslo, Adam R., Minor, Daniel L.
Publicado 2018

A glutamate switch controls voltage-sensitive phosphatase function

por Liu, Lijun, Kohout, Susy C., Xu, Qiang, Müller, Simone, Kimberlin, Christopher R., Isacoff, Ehud Y., Minor, Daniel L.
Publicado 2012

A High-Throughput Functional Screen Identifies Small Molecule Regulators of Temperature- and Mechano-Sensitive K(2P) Channels

por Bagriantsev, Sviatoslav N., Ang, Kean-Hooi, Gallardo-Godoy, Alejandra, Clark, Kimberly A., Arkin, Michelle R., Renslo, Adam R., Minor, Daniel L.
Publicado 2013

Selection of Inhibitor-Resistant Viral Potassium Channels Identifies a Selectivity Filter Site that Affects Barium and Amantadine Block

por Chatelain, Franck C., Gazzarrini, Sabrina, Fujiwara, Yuichiro, Arrigoni, Cristina, Domigan, Courtney, Ferrara, Giuseppina, Pantoja, Carlos, Thiel, Gerhard, Moroni, Anna, Minor, Daniel L.
Publicado 2009

2007 Annual progress report synopsis of the Center for Structures of Membrane Proteins

por Stroud, Robert M., Choe, Senyon, Holton, James, Kaback, H. Ronald, Kwiatkowski, Witek, Minor, Daniel L., Riek, Roland, Sali, Andrej, Stahlberg, Henning, Harries, William
Publicado 2009

K(2P) channel C-type gating involves asymmetric selectivity filter order-disorder transitions

por Lolicato, Marco, Natale, Andrew M., Abderemane-Ali, Fayal, Crottès, David, Capponi, Sara, Duman, Ramona, Wagner, Armin, Rosenberg, John M., Grabe, Michael, Minor, Daniel L.
Publicado 2020

Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family

por Chen, Zhou, Zakrzewska, Sandra, Hajare, Holly S., Alvarez-Buylla, Aurora, Abderemane-Ali, Fayal, Bogan, Maximiliana, Ramirez, Dave, O’Connell, Lauren A., Du Bois, J., Minor, Daniel L.
Publicado 2022

Stapled Voltage-Gated Calcium Channel (Ca(V)) α-Interaction Domain (AID) Peptides Act As Selective Protein–Protein Interaction Inhibitors of Ca(V) Function

por Findeisen, Felix, Campiglio, Marta, Jo, Hyunil, Abderemane-Ali, Fayal, Rumpf, Christine H., Pope, Lianne, Rossen, Nathan D., Flucher, Bernhard E., DeGrado, William F., Minor, Daniel L.
Publicado 2017

Development of covalent chemogenetic K(2P) channel activators

por Deal, Parker E., Lee, Haerim, Mondal, Abhisek, Lolicato, Marco, de Mendonca, Philipe Ribeiro Furtado, Black, Holly, El-Hilali, Xochina, Bryant, Clifford, Isacoff, Ehud Y., Renslo, Adam R., Minor, Daniel L.
Publicado 2023

Chemical Informatics and Target Identification in a Zebrafish Phenotypic Screen

por Laggner, Christian, Kokel, David, Setola, Vincent, Tolia, Alexandra, Lin, Henry, Irwin, John J., Keiser, Michael J., Cheung, Chung Yan J., Minor, Daniel L., Roth, Bryan L., Peterson, Randall T., Shoichet, Brian K.
Publicado 2011

Selective posttranslational inhibition of Ca(V)β(1)-associated voltage-dependent calcium channels with a functionalized nanobody

por Morgenstern, Travis J., Nirwan, Neha, Hernández-Ochoa, Erick O., Bibollet, Hugo, Choudhury, Papiya, Laloudakis, Yianni D., Ben Johny, Manu, Bannister, Roger A., Schneider, Martin F., Minor, Daniel L., Colecraft, Henry M.
Publicado 2022