Protein kinase inhibitor ceritinib blocks ectonucleotidase CD39 – a promising target for cancer immunotherapy

por Schäkel, Laura, Mirza, Salahuddin, Winzer, Riekje, Lopez, Vittoria, Idris, Riham, Al-Hroub, Haneen, Pelletier, Julie, Sévigny, Jean, Tolosa, Eva, Müller, Christa E
Publicado 2022

Nucleotide Analog ARL67156 as a Lead Structure for the Development of CD39 and Dual CD39/CD73 Ectonucleotidase Inhibitors

por Schäkel, Laura, Schmies, Constanze C., Idris, Riham M., Luo, Xihuan, Lee, Sang-Yong, Lopez, Vittoria, Mirza, Salahuddin, Vu, The Hung, Pelletier, Julie, Sévigny, Jean, Namasivayam, Vigneshwaran, Müller, Christa E.
Publicado 2020

Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39

por Lopez, Vittoria, Schäkel, Laura, Schuh, H. J. Maximilian, Schmidt, Michael S., Mirza, Salahuddin, Renn, Christian, Pelletier, Julie, Lee, Sang-Yong, Sévigny, Jean, Alban, Susanne, Bendas, Gerd, Müller, Christa E.
Publicado 2021

Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) – a promising target for the immunotherapy of cancer

por Lopez, Vittoria, Schuh, H. J. Maximilian, Mirza, Salahuddin, Vaaßen, Victoria J., Schmidt, Michael S., Sylvester, Katharina, Idris, Riham M., Renn, Christian, Schäkel, Laura, Pelletier, Julie, Sévigny, Jean, Naggi, Annamaria, Scheffler, Björn, Lee, Sang-Yong, Bendas, Gerd, Müller, Christa E.
Publicado 2023

Targeting the Main Protease of SARS‐CoV‐2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors

por Breidenbach, Julian, Lemke, Carina, Pillaiyar, Thanigaimalai, Schäkel, Laura, Al Hamwi, Ghazl, Diett, Miriam, Gedschold, Robin, Geiger, Nina, Lopez, Vittoria, Mirza, Salahuddin, Namasivayam, Vigneshwaran, Schiedel, Anke C., Sylvester, Katharina, Thimm, Dominik, Vielmuth, Christin, Phuong Vu, Lan, Zyulina, Maria, Bodem, Jochen, Gütschow, Michael, Müller, Christa E.
Publicado 2021