Reproducible Single-Cell Genomic Research in Pulmonary and Critical Care Medicine

por Eickelberg, Oliver, Misharin, Alexander V., Sime, Patricia J.
Publicado 2020

Modeling human influenza infection in the laboratory

por Radigan, Kathryn A, Misharin, Alexander V, Chi, Monica, Budinger, GR Scott
Publicado 2015

The heterogeneity of lung macrophages in the susceptibility to disease

por Morales-Nebreda, Luisa, Misharin, Alexander V., Perlman, Harris, Budinger, G.R. Scott
Publicado 2015

Development of a new humanized mouse model to study acute inflammatory arthritis

por Misharin, Alexander V, Haines, G Kenneth, Rose, Shawn, Gierut, Angelical K, Hotchkiss, Richard S, Perlman, Harris
Publicado 2012

Expression of ACE2—a Key SARS-CoV-2 Entry Factor—Is Not Increased in the Nasal Mucosa of People with Cystic Fibrosis

por Sala, Marc A., Markov, Nikolay S., Politanska, Yuliya, Abdala-Valencia, Hiam, Misharin, Alexander V., Jain, Manu
Publicado 2022

Development of a novel humanized mouse model to study bronchopulmonary dysplasia

por Birkett, Rob, Newar, Janu, Sharma, Abhineet M., Lin, Erika, Blank, Lillian, Swaminathan, Suchitra, Misharin, Alexander, Mestan, Karen K.
Publicado 2023

Biologically informed deep learning to query gene programs in single-cell atlases

por Lotfollahi, Mohammad, Rybakov, Sergei, Hrovatin, Karin, Hediyeh-zadeh, Soroor, Talavera-López, Carlos, Misharin, Alexander V., Theis, Fabian J.
Publicado 2023

Critical role of synovial tissue–resident macrophage niche in joint homeostasis and suppression of chronic inflammation

por Huang, Qi-Quan, Doyle, Renee, Chen, Shang-Yang, Sheng, Qicong, Misharin, Alexander V., Mao, Qinwen, Winter, Deborah R., Pope, Richard M.
Publicado 2021

Placental dysfunction influences fetal monocyte subpopulation gene expression in preterm birth

por Sharma, Abhineet M., Birkett, Robert, Lin, Erika T., Ernst, Linda M., Grobman, William A., Swaminathan, Suchitra, Abdala-Valencia, Hiam, Misharin, Alexander V., Bartom, Elizabeth T., Mestan, Karen K.
Publicado 2022

The Effect of Rosuvastatin in a Murine Model of Influenza A Infection

por Radigan, Kathryn A., Urich, Daniela, Misharin, Alexander V., Chiarella, Sergio E., Soberanes, Saul, Gonzalez, Angel, Perlman, Harris, Wunderink, Richard G., Budinger, G. R. Scott, Mutlu, Gökhan M.
Publicado 2012

The PYRIN domain-only protein POP2 inhibits inflammasome priming and activation

por Ratsimandresy, Rojo A., Chu, Lan H., Khare, Sonal, de Almeida, Lucia, Gangopadhyay, Anu, Indramohan, Mohanalaxmi, Misharin, Alexander V., Greaves, David R., Perlman, Harris, Dorfleutner, Andrea, Stehlik, Christian
Publicado 2017

CD11b suppresses TLR activation of nonclassical monocytes to reduce primary graft dysfunction after lung transplantation

por Querrey, Melissa, Chiu, Stephen, Lecuona, Emilia, Wu, Qiang, Sun, Haiying, Anderson, Megan, Kelly, Megan, Ravi, Sowmya, Misharin, Alexander V., Kreisel, Daniel, Bharat, Ankit, Budinger, G.R. Scott
Publicado 2022

Mapping single-cell data to reference atlases by transfer learning

por Lotfollahi, Mohammad, Naghipourfar, Mohsen, Luecken, Malte D., Khajavi, Matin, Büttner, Maren, Wagenstetter, Marco, Avsec, Žiga, Gayoso, Adam, Yosef, Nir, Interlandi, Marta, Rybakov, Sergei, Misharin, Alexander V., Theis, Fabian J.
Publicado 2021

Impaired Clearance of Influenza A Virus in Obese, Leptin Receptor Deficient Mice Is Independent of Leptin Signaling in the Lung Epithelium and Macrophages

por Radigan, Kathryn A., Morales-Nebreda, Luisa, Soberanes, Saul, Nicholson, Trevor, Nigdelioglu, Recep, Cho, Takugo, Chi, Monica, Hamanaka, Robert B., Misharin, Alexander V., Perlman, Harris, Budinger, G. R. Scott, Mutlu, Gökhan M.
Publicado 2014

ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model

por Archer, Amy M., Saber, Rana, Rose, Shawn, Shaffer, Alexander, Misharin, Alexander V., Tsai, FuNien, Haines III, G. Kenneth, Dominguez, Salina, Eren, Mesut, Vaughan, Douglas E., Cuda, Carla M., Perlman, Harris
Publicado 2016

Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner

por Cuda, Carla M., Misharin, Alexander V., Khare, Sonal, Saber, Rana, Tsai, FuNien, Archer, Amy M., Homan, Philip J., Haines, G. Kenneth, Hutcheson, Jack, Dorfleutner, Andrea, Budinger, G. R. Scott, Stehlik, Christian, Perlman, Harris
Publicado 2015

Lung transplantation for patients with severe COVID-19

por Bharat, Ankit, Querrey, Melissa, Markov, Nikolay S., Kim, Samuel, Kurihara, Chitaru, Garza-Castillon, Rafael, Manerikar, Adwaiy, Shilatifard, Ali, Tomic, Rade, Politanska, Yuliya, Abdala-Valencia, Hiam, Yeldandi, Anjana V., Lomasney, Jon W., Misharin, Alexander V., Budinger, G. R. Scott
Publicado 2020

The PYRIN domain-only protein POP3 inhibits AIM2-like receptor inflammasomes and regulates responses to DNA virus infections

por Khare, Sonal, Ratsimandresy, Rojo A., de Almeida, Lúcia, Cuda, Carla M., Rellick, Stephanie L., Misharin, Alexander V., Wallin, Melissa C., Gangopadhyay, Anu, Forte, Eleonora, Gottwein, Eva, Perlman, Harris, Reed, John C., Greaves, David R., Dorfleutner, Andrea, Stehlik, Christian
Publicado 2014

2560. Individual Meropenem Epithelial Lining Fluid and Plasma PK/PD Target Attainment in Patients with Pneumonia

por Rohani, Roxane, Yarnold, Paul R, Scheetz, Marc H, Neely, Michael N, Kang, Mengjia, Donnelly, Helen K, Dedicatoria, Kay, Nozick, Sophia, Medernach, Rachel, Hauser, Alan R, Ozer, Egon A, Diaz, Estefani, Misharin, Alexander V, Wunderink, Richard G, Rhodes, Nathaniel J
Publicado 2023

Inflammatory pathways are upregulated in the nasal epithelium in patients with idiopathic pulmonary fibrosis

por Sala, Marc A., Balderas-Martínez, Yalbi Itzel, Buendía-Roldan, Ivette, Abdala-Valencia, Hiam, Nam, Kiwon, Jain, Manu, Bhorade, Sangeeta, Bharat, Ankit, Reyfman, Paul A., Ridge, Karen M., Pardo, Annie, Sznajder, Jacob I., Budinger, G. R. Scott, Misharin, Alexander V., Selman, Moises
Publicado 2018