The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer

por Rodgers, Samuel J., Mitchell, Christina A., Ooms, Lisa M.
Publicado 2023

The FDA-Approved Drug Pyrvinium Selectively Targets ER(+) Breast Cancer Cells with High INPP4B Expression

por Rodgers, Samuel J., Ooms, Lisa M., Mitchell, Christina A.
Publicado 2022

Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases

por Rodgers, Samuel J., Ferguson, Daniel T., Mitchell, Christina A., Ooms, Lisa M.
Publicado 2017

PTEN and Other PtdIns(3,4,5)P(3) Lipid Phosphatases in Breast Cancer

por Csolle, Mariah P., Ooms, Lisa M., Papa, Antonella, Mitchell, Christina A.
Publicado 2020

Superresolution Microscopy Reveals Distinct Phosphoinositide Subdomains Within the Cilia Transition Zone

por Conduit, Sarah E., Davies, Elizabeth M., Fulcher, Alex J., Oorschot, Viola, Mitchell, Christina A.
Publicado 2021

Autophosphorylation of serine 608 in the p85 regulatory subunit of wild type or cancer-associated mutants of phosphoinositide 3-kinase does not affect its lipid kinase activity

por Layton, Meredith J, Saad, Mirette, Church, Nicole L, Pearson, Richard B, Mitchell, Christina A, Phillips, Wayne A
Publicado 2012

Assessing the subcellular distribution of oncogenic phosphoinositide 3-kinase using microinjection into live cells

por Layton, Meredith J., Rynkiewicz, Natalie K., Ivetac, Ivan, Horan, Kristy A., Mitchell, Christina A., Phillips, Wayne A.
Publicado 2014

Autophagic lysosome reformation in health and disease

por Nanayakkara, Randini, Gurung, Rajendra, Rodgers, Samuel J., Eramo, Matthew J., Ramm, Georg, Mitchell, Christina A., McGrath, Meagan J.
Publicado 2022

PI(4,5)P(2)-dependent regulation of endothelial tip cell specification contributes to angiogenesis

por Davies, Elizabeth M., Gurung, Rajendra, Le, Kai Qin, Roan, Katherine T. T., Harvey, Richard P., Mitchell, Geraldine M., Schwarz, Quenten, Mitchell, Christina A.
Publicado 2023

A Mutation in Synaptojanin 2 Causes Progressive Hearing Loss in the ENU-Mutagenised Mouse Strain Mozart

por Manji, Shehnaaz S. M., Williams, Louise H., Miller, Kerry A., Ooms, Lisa M., Bahlo, Melanie, Mitchell, Christina A., Dahl, Hans-Henrik M.
Publicado 2011

The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin

por Dyson, Jennifer M., O'Malley, Cindy J., Becanovic, Jelena, Munday, Adam D., Berndt, Michael C., Coghill, Imogen D., Nandurkar, Harshal H., Ooms, Lisa M., Mitchell, Christina A.
Publicado 2001

Deterministic early endosomal maturations emerge from a stochastic trigger-and-convert mechanism

por York, Harrison M., Joshi, Kunaal, Wright, Charles S., Kreplin, Laura Z., Rodgers, Samuel J., Moorthi, Ullhas K., Gandhi, Hetvi, Patil, Abhishek, Mitchell, Christina A., Iyer-Biswas, Srividya, Arumugam, Senthil
Publicado 2023

FHL1 Reduces Dystrophy in Transgenic Mice Overexpressing FSHD Muscular Dystrophy Region Gene 1 (FRG1)

por Feeney, Sandra J., McGrath, Meagan J., Sriratana, Absorn, Gehrig, Stefan M., Lynch, Gordon S., D’Arcy, Colleen E., Price, John T., McLean, Catriona A., Tupler, Rossella, Mitchell, Christina A.
Publicado 2015

Endosome maturation links PI3Kα signaling to lysosome repopulation during basal autophagy

por Rodgers, Samuel J, Jones, Emily I, Arumugam, Senthil, Hamila, Sabryn A, Danne, Jill, Gurung, Rajendra, Eramo, Matthew J, Nanayakkara, Randini, Ramm, Georg, McGrath, Meagan J, Mitchell, Christina A
Publicado 2022

Identification of FHL1 as a regulator of skeletal muscle mass: implications for human myopathy

por Cowling, Belinda S., McGrath, Meagan J., Nguyen, Mai-Anh, Cottle, Denny L., Kee, Anthony J., Brown, Susan, Schessl, Joachim, Zou, Yaqun, Joya, Josephine, Bönnemann, Carsten G., Hardeman, Edna C., Mitchell, Christina A.
Publicado 2008

Functional and Phenotypic Characterisations of Common Syngeneic Tumour Cell Lines as Estrogen Receptor-Positive Breast Cancer Models

por Lambouras, Maria, Roelofs, Charlotte, Pereira, Melrine, Gruber, Emily, Vieusseux, Jessica L., Lanteri, Patrick, Johnstone, Cameron N., Muntz, Fenella, O’Toole, Sandra, Ooms, Lisa M., Mitchell, Christina A., Anderson, Robin L., Britt, Kara L.
Publicado 2023

INPP5E regulates phosphoinositide-dependent cilia transition zone function

por Dyson, Jennifer M., Conduit, Sarah E., Feeney, Sandra J., Hakim, Sandra, DiTommaso, Tia, Fulcher, Alex J., Sriratana, Absorn, Ramm, Georg, Horan, Kristy A., Gurung, Rajendra, Wicking, Carol, Smyth, Ian, Mitchell, Christina A.
Publicado 2017

Defective lysosome reformation during autophagy causes skeletal muscle disease

por McGrath, Meagan J., Eramo, Matthew J., Gurung, Rajendra, Sriratana, Absorn, Gehrig, Stefan M., Lynch, Gordon S., Lourdes, Sonia Raveena, Koentgen, Frank, Feeney, Sandra J., Lazarou, Michael, McLean, Catriona A., Mitchell, Christina A.
Publicado 2021

Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing

por Carroll, Bernadette, Nelson, Glyn, Rabanal-Ruiz, Yoana, Kucheryavenko, Olena, Dunhill-Turner, Natasha A., Chesterman, Charlotte C., Zahari, Qabil, Zhang, Tong, Conduit, Sarah E., Mitchell, Christina A., Maddocks, Oliver D.K., Lovat, Penny, von Zglinicki, Thomas, Korolchuk, Viktor I.
Publicado 2017

Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation

por Ma, Xiuquan, Zhang, Luxi, Song, Jiangning, Nguyen, Elizabeth, Lee, Rachel S., Rodgers, Samuel J., Li, Fuyi, Huang, Cheng, Schittenhelm, Ralf B., Chan, Howard, Chheang, Chanly, Wu, Jianmin, Brown, Kristin K., Mitchell, Christina A., Simpson, Kaylene J., Daly, Roger J.
Publicado 2019