Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family

por Haft, Daniel H, Basu, Malay Kumar, Mitchell, Douglas A
Publicado 2010

YcaO domains utilize ATP to activate amide backbones during peptide cyclodehydrations

por Dunbar, Kyle L, Melby, Joel O, Mitchell, Douglas A
Publicado 2012

The genomic landscape of ribosomal peptides containing thiazole and oxazole heterocycles

por Cox, Courtney L., Doroghazi, James R., Mitchell, Douglas A.
Publicado 2015

Crystal structure and absolute configuration of (3S,4aS,8aS)-N-tert-butyl-2-[(S)-3-(2-chloro-4-nitro­benzamido)-2-hy­droxy­prop­yl]deca­hydro­isoquinoline-3-carboxamide and (3S,4aS...

por Maxson, Tucker, Bertke, Jeffery A., Gray, Danielle L., Mitchell, Douglas A.
Publicado 2015

Post-translational thioamidation of methyl-coenzyme M reductase, a key enzyme in methanogenic and methanotrophic Archaea

por Nayak, Dipti D, Mahanta, Nilkamal, Mitchell, Douglas A, Metcalf, William W
Publicado 2017

RadicalSAM.org: A Resource to Interpret Sequence-Function Space and Discover New Radical SAM Enzyme Chemistry

por Oberg, Nils, Precord, Timothy W., Mitchell, Douglas A., Gerlt, John A.
Publicado 2021

Discovery of biaryl macrocyclic peptides with C-terminal β-amino-α-keto acid groups

por Nguyen, Dinh T., Zhu, Lingyang, Mitchell, Douglas A., van der Donk, Wilfred A.
Publicado 2023

A Prevalent Peptide-Binding Domain Guides Ribosomal Natural Product Biosynthesis

por Burkhart, Brandon J., Hudson, Graham A., Dunbar, Kyle L., Mitchell, Douglas A.
Publicado 2015

Mechanistic Basis for Ribosomal Peptide Backbone Modifications

por Dong, Shi-Hui, Liu, Andi, Mahanta, Nilkamal, Mitchell, Douglas A., Nair, Satish K.
Publicado 2019

McrD binds asymmetrically to methyl-coenzyme M reductase improving active-site accessibility during assembly

por Chadwick, Grayson L., Joiner, Aaron M. N., Ramesh, Sangeetha, Mitchell, Douglas A., Nayak, Dipti D.
Publicado 2023

Mechanism of a Class C Radical S-Adenosyl-l-methionine Thiazole Methyl Transferase

por Zhang, Zhengan, Mahanta, Nilkamal, Hudson, Graham A., Mitchell, Douglas A., van der Donk, Wilfred A.
Publicado 2017

In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin

por Hudson, Graham A., Zhang, Zhengan, Tietz, Jonathan I., Mitchell, Douglas A., van der Donk, Wilfred A.
Publicado 2015

Chimeric Leader Peptides for the Generation of Non-Natural Hybrid RiPP Products

por Burkhart, Brandon J., Kakkar, Nidhi, Hudson, Graham A., van der Donk, Wilfred A., Mitchell, Douglas A.
Publicado 2017

RRE-Finder: a Genome-Mining Tool for Class-Independent RiPP Discovery

por Kloosterman, Alexander M., Shelton, Kyle E., van Wezel, Gilles P., Medema, Marnix H., Mitchell, Douglas A.
Publicado 2020

Evaluating the detectability of methane point sources from satellite observing systems using microscale modeling

por Bhardwaj, Piyush, Kumar, Rajesh, Mitchell, Douglas A., Randles, Cynthia A., Downey, Nicole, Blewitt, Doug, Kosovic, Branko
Publicado 2022

Catalytic Site Proximity Profiling for Functional Unification of Sequence-Diverse Radical S-Adenosylmethionine Enzymes

por Precord, Timothy W., Ramesh, Sangeetha, Dommaraju, Shravan R., Harris, Lonnie A., Kille, Bryce L., Mitchell, Douglas A.
Publicado 2023

Nucleophilic 1,4-Additions for Natural Product Discovery

por Cox, Courtney L., Tietz, Jonathan I., Sokolowski, Karol, Melby, Joel O., Doroghazi, James R., Mitchell, Douglas A.
Publicado 2014

Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis

por Dunbar, Kyle L., Chekan, Jonathan R., Cox, Courtney L., Burkhart, Brandon J., Nair, Satish K., Mitchell, Douglas A.
Publicado 2014

Functional Elucidation of TfuA in Peptide Backbone Thioamidation

por Liu, Andi, Si, Yuanyuan, Dong, Shi-Hui, Mahanta, Nilkamal, Penkala, Haley N., Nair, Satish K., Mitchell, Douglas A.
Publicado 2021

Accessing Diverse Pyridine-Based Macrocyclic Peptides by a Two-Site Recognition Pathway

por Nguyen, Dinh T., Le, Tung T., Rice, Andrew J., Hudson, Graham A., van der Donk, Wilfred A., Mitchell, Douglas A.
Publicado 2022