The role of Ca(2+) in the activity of Mycobacterium tuberculosis DNA gyrase

por Karkare, Shantanu, Yousafzai, Faridoon, Mitchenall, Lesley A., Maxwell, Anthony
Publicado 2012

Application of a Novel Microtitre Plate-Based Assay for the Discovery of New Inhibitors of DNA Gyrase and DNA Topoisomerase VI

por Taylor, James A., Mitchenall, Lesley A., Rejzek, Martin, Field, Robert A., Maxwell, Anthony
Publicado 2013

Vibrio cholerae ParE2 Poisons DNA Gyrase via a Mechanism Distinct from Other Gyrase Inhibitors

por Yuan, Jie, Sterckx, Yann, Mitchenall, Lesley A., Maxwell, Anthony, Loris, Remy, Waldor, Matthew K.
Publicado 2010

A rapid high-resolution method for resolving DNA topoisomers

por Mitchenall, Lesley A., Hipkin, Rachel E., Piperakis, Michael M., Burton, Nicolas P., Maxwell, Anthony
Publicado 2018

DNA G-segment bending is not the sole determinant of topology simplification by type II DNA topoisomerases

por Thomson, Neil H., Santos, Sergio, Mitchenall, Lesley A., Stuchinskaya, Tanya, Taylor, James A., Maxwell, Anthony
Publicado 2014

DNA Gyrase Is the Target for the Quinolone Drug Ciprofloxacin in Arabidopsis thaliana

por Evans-Roberts, Katherine M., Mitchenall, Lesley A., Wall, Melisa K., Leroux, Julie, Mylne, Joshua S., Maxwell, Anthony
Publicado 2016

Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by Gram-negative and Gram-positive type II DNA topoisomerases

por Richter, Sara N., Giaretta, Giulia, Comuzzi, Valentina, Leo, Elisabetta, Mitchenall, Lesley A., Fisher, L. Mark, Maxwell, Anthony, Palumbo, Manlio
Publicado 2007

Use of divalent metal ions in the DNA cleavage reaction of topoisomerase IV

por Pitts, Steven L., Liou, Grace F., Mitchenall, Lesley A., Burgin, Alex B., Maxwell, Anthony, Neuman, Keir C., Osheroff, Neil
Publicado 2011

The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic

por Feng, Lipeng, Mundy, Julia E. A., Stevenson, Clare E. M., Mitchenall, Lesley A., Lawson, David M., Mi, Kaixia, Maxwell, Anthony
Publicado 2021

A Common Origin for the Bacterial Toxin-Antitoxin Systems parD and ccd, Suggested by Analyses of Toxin/Target and Toxin/Antitoxin Interactions

por Smith, Andrew B., López-Villarejo, Juan, Diago-Navarro, Elizabeth, Mitchenall, Lesley A., Barendregt, Arjan, Heck, Albert J., Lemonnier, Marc, Maxwell, Anthony, Díaz-Orejas, Ramón
Publicado 2012

The Naphthoquinone Diospyrin Is an Inhibitor of DNA Gyrase with a Novel Mechanism of Action

por Karkare, Shantanu, Chung, Terence T. H., Collin, Frederic, Mitchenall, Lesley A., McKay, Adam R., Greive, Sandra J., Meyer, Jacobus J. M., Lall, Namrita, Maxwell, Anthony
Publicado 2013

The dimer state of GyrB is an active form: implications for the initial complex assembly and processive strand passage

por Wu, Jinjun, Zhang, Zhiping, Mitchenall, Lesley A., Maxwell, Anthony, Deng, Jiaoyu, Zhang, Hongtai, Zhou, Ying, Chen, Yuan-yuan, Wang, Da-Cheng, Zhang, Xian-En, Bi, Lijun
Publicado 2011

Single-molecule imaging of DNA gyrase activity in living Escherichia coli

por Stracy, Mathew, Wollman, Adam J M, Kaja, Elzbieta, Gapinski, Jacek, Lee, Ji-Eun, Leek, Victoria A, McKie, Shannon J, Mitchenall, Lesley A, Maxwell, Anthony, Sherratt, David J, Leake, Mark C, Zawadzki, Pawel
Publicado 2019

Structural and mechanistic analysis of ATPase inhibitors targeting mycobacterial DNA gyrase

por Henderson, Sara R, Stevenson, Clare E M, Malone, Brandon, Zholnerovych, Yelyzaveta, Mitchenall, Lesley A, Pichowicz, Mark, McGarry, David H, Cooper, Ian R, Charrier, Cedric, Salisbury, Anne-Marie, Lawson, David M, Maxwell, Anthony
Publicado 2020

Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides

por Pyne, Alice L. B., Noy, Agnes, Main, Kavit H. S., Velasco-Berrelleza, Victor, Piperakis, Michael M., Mitchenall, Lesley A., Cugliandolo, Fiorella M., Beton, Joseph G., Stevenson, Clare E. M., Hoogenboom, Bart W., Bates, Andrew D., Maxwell, Anthony, Harris, Sarah A.
Publicado 2021