Computational Identification of Mechanistic Factors That Determine the Timing and Intensity of the Inflammatory Response

por Nagaraja, Sridevi, Reifman, Jaques, Mitrophanov, Alexander Y.
Publicado 2015

Mechanistic Modeling of the Effects of Acidosis on Thrombin Generation

por Mitrophanov, Alexander Y., Rosendaal, Frits R., Reifman, Jaques
Publicado 2015

Computational Study of Thrombus Formation and Clotting Factor Effects under Venous Flow Conditions

por Govindarajan, Vijay, Rakesh, Vineet, Reifman, Jaques, Mitrophanov, Alexander Y.
Publicado 2016

Evolution and Dynamics of Regulatory Architectures Controlling Polymyxin B Resistance in Enteric Bacteria

por Mitrophanov, Alexander Y., Jewett, Mollie W., Hadley, Tricia J., Groisman, Eduardo A.
Publicado 2008

Computational analysis identifies putative prognostic biomarkers of pathological scarring in skin wounds

por Nagaraja, Sridevi, Chen, Lin, DiPietro, Luisa A., Reifman, Jaques, Mitrophanov, Alexander Y.
Publicado 2018

LPS‐stimulated NF‐κB p65 dynamic response marks the initiation of TNF expression and transition to IL‐10 expression in RAW 264.7 macrophages

por Hobbs, Stuart, Reynoso, Marinaliz, Geddis, Alyssa V., Mitrophanov, Alexander Y., Matheny, Ronald W.
Publicado 2018

Predictive Approach Identifies Molecular Targets and Interventions to Restore Angiogenesis in Wounds With Delayed Healing

por Nagaraja, Sridevi, Chen, Lin, DiPietro, Luisa A., Reifman, Jaques, Mitrophanov, Alexander Y.
Publicado 2019

Impact of Tissue Factor Localization on Blood Clot Structure and Resistance under Venous Shear

por Govindarajan, Vijay, Zhu, Shu, Li, Ruizhi, Lu, Yichen, Diamond, Scott L., Reifman, Jaques, Mitrophanov, Alexander Y.
Publicado 2018

Microfluidic and computational study of structural properties and resistance to flow of blood clots under arterial shear

por Mitrophanov, Alexander Y., Govindarajan, Vijay, Zhu, Shu, Li, Ruizhi, Lu, Yichen, Diamond, Scott L., Reifman, Jaques
Publicado 2019

PKM2 dictates the poised chromatin state of PFKFB3 promoter to enhance breast cancer progression

por Pandkar, Madhura R, Raveendran, Adarsh, Biswas, Kajal, Mutnuru, Srinivas Abhishek, Mishra, Jharna, Samaiya, Atul, Malys, Tyler, Mitrophanov, Alexander Y, Sharan, Shyam K, Shukla, Sanjeev
Publicado 2023

Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants

por Sahu, Sounak, Sullivan, Teresa L., Mitrophanov, Alexander Y., Galloux, Mélissa, Nousome, Darryl, Southon, Eileen, Caylor, Dylan, Mishra, Arun Prakash, Evans, Christine N., Clapp, Michelle E., Burkett, Sandra, Malys, Tyler, Chari, Raj, Biswas, Kajal, Sharan, Shyam K.
Publicado 2023

Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs

por Biswas, Kajal, Mitrophanov, Alexander Y., Sahu, Sounak, Sullivan, Teresa, Southon, Eileen, Nousome, Darryl, Reid, Susan, Narula, Sakshi, Smolen, Julia, Sengupta, Trisha, Riedel-Topper, Maximilian, Kapoor, Medha, Babbar, Anav, Stauffer, Stacey, Cleveland, Linda, Tandon, Mayank, Malys, Tyler, Sharan, Shyam K.
Publicado 2023