The mitochondrial SIR2 related protein 2 (SIR2RP2) impacts Leishmania donovani growth and infectivity

por Mittal, Nimisha, Muthuswami, Rohini, Madhubala, Rentala
Publicado 2017

Rapid diagnosis of Leishmania infection with a portable loop-mediated isothermal amplification device

por Puri, Madhu, Brar, Harsimran Kaur, Mittal, Nimisha, Madan, Evanka, Srinivasan, Rajesh, Rawat, Kapil, Moulik, Srija, Chatterjee, Mitali, Gorthi, Sai Siva, Muthuswami, Rohini, Madhubala, Rentala
Publicado 2021

PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum

por Rocamora, Frances, Gupta, Purva, Istvan, Eva S., Luth, Madeline R., Carpenter, Emma F., Kümpornsin, Krittikorn, Sasaki, Erika, Calla, Jaeson, Mittal, Nimisha, Carolino, Krypton, Owen, Edward, Llinás, Manuel, Ottilie, Sabine, Goldberg, Daniel E., Lee, Marcus C. S., Winzeler, Elizabeth A.
Publicado 2021

Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer

por Abacha, Yabalu Z., Forkuo, Arnold Donkor, Gbedema, Stephen Y., Mittal, Nimisha, Ottilie, Sabine, Rocamora, Frances, Winzeler, Elizabeth A., van Schalkwyk, Donelly A., Kelly, John M., Taylor, Martin C., Reader, Janette, Birkholtz, Lyn-Marie, Lisgarten, David R., Cockcroft, Jeremy K., Lisgarten, John N., Palmer, Rex A., Talbert, Rosemary C., Shnyder, Steven D., Wright, Colin W.
Publicado 2022

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity

por Vanaerschot, Manu, Murithi, James M., Pasaje, Charisse Flerida A., Ghidelli-Disse, Sonja, Dwomoh, Louis, Bird, Megan, Spottiswoode, Natasha, Mittal, Nimisha, Arendse, Lauren B., Owen, Edward S., Wicht, Kathryn J., Siciliano, Giulia, Bösche, Markus, Yeo, Tomas, Kumar, T.R. Santha, Mok, Sachel, Carpenter, Emma F., Giddins, Marla J., Sanz, Olalla, Ottilie, Sabine, Alano, Pietro, Chibale, Kelly, Llinás, Manuel, Uhlemann, Anne-Catrin, Delves, Michael, Tobin, Andrew B., Doerig, Christian, Winzeler, Elizabeth A., Lee, Marcus C.S., Niles, Jacquin C., Fidock, David A.
Publicado 2020

Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box

por Reader, Janette, van der Watt, Mariëtte E., Taylor, Dale, Le Manach, Claire, Mittal, Nimisha, Ottilie, Sabine, Theron, Anjo, Moyo, Phanankosi, Erlank, Erica, Nardini, Luisa, Venter, Nelius, Lauterbach, Sonja, Bezuidenhout, Belinda, Horatscheck, Andre, van Heerden, Ashleigh, Spillman, Natalie J., Cowell, Anne N., Connacher, Jessica, Opperman, Daniel, Orchard, Lindsey M., Llinás, Manuel, Istvan, Eva S., Goldberg, Daniel E., Boyle, Grant A., Calvo, David, Mancama, Dalu, Coetzer, Theresa L., Winzeler, Elizabeth A., Duffy, James, Koekemoer, Lizette L., Basarab, Gregory, Chibale, Kelly, Birkholtz, Lyn-Marié
Publicado 2021

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

por Summers, Robert L., Pasaje, Charisse Flerida A., Pisco, Joao P., Striepen, Josefine, Luth, Madeline R., Kumpornsin, Krittikorn, Carpenter, Emma F., Munro, Justin T., Lin, De, Plater, Andrew, Punekar, Avinash S., Shepherd, Andrew M., Shepherd, Sharon M., Vanaerschot, Manu, Murithi, James M., Rubiano, Kelly, Akidil, Aslı, Ottilie, Sabine, Mittal, Nimisha, Dilmore, A. Hazel, Won, Madalyn, Mandt, Rebecca E.K., McGowen, Kerry, Owen, Edward, Walpole, Chris, Llinás, Manuel, Lee, Marcus C.S., Winzeler, Elizabeth A., Fidock, David A., Gilbert, Ian H., Wirth, Dyann F., Niles, Jacquin C., Baragaña, Beatriz, Lukens, Amanda K.
Publicado 2022

Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome

por Xie, Stanley C., Metcalfe, Riley D., Mizutani, Hirotake, Puhalovich, Tanya, Hanssen, Eric, Morton, Craig J., Du, Yawei, Dogovski, Con, Huang, Shih-Chung, Ciavarri, Jeffrey, Hales, Paul, Griffin, Robert J., Cohen, Lawrence H., Chuang, Bei-Ching, Wittlin, Sergio, Deni, Ioanna, Yeo, Tomas, Ward, Kurt E., Barry, Daniel C., Liu, Boyin, Gillett, David L., Crespo-Fernandez, Benigno F., Ottilie, Sabine, Mittal, Nimisha, Churchyard, Alisje, Ferguson, Daniel, Aguiar, Anna Caroline C., Guido, Rafael V. C., Baum, Jake, Hanson, Kirsten K., Winzeler, Elizabeth A., Gamo, Francisco-Javier, Fidock, David A., Baud, Delphine, Parker, Michael W., Brand, Stephen, Dick, Lawrence R., Griffin, Michael D. W., Gould, Alexandra E., Tilley, Leann
Publicado 2021