PARP Inhibitors for Sensitization of Alkylation Chemotherapy in Glioblastoma: Impact of Blood-Brain Barrier and Molecular Heterogeneity

por Gupta, Shiv K., Smith, Emily J., Mladek, Ann C., Tian, Shulan, Decker, Paul A., Kizilbash, Sani H., Kitange, Gaspar J., Sarkaria, Jann N.
Publicado 2019

Quantitative Analysis of Tyrosine Phosphorylation from FFPE Tissues Reveals Patient-Specific Signaling Networks

por Kohale, Ishwar N., Burgenske, Danielle M., Mladek, Ann C., Bakken, Katrina K., Kuang, Jenevieve, Boughey, Judy C., Wang, Liewei, Carter, Jodi M., Haura, Eric B., Goetz, Matthew P., Sarkaria, Jann N., White, Forest M.
Publicado 2021

Protein kinase C(ι) and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities

por Kenchappa, Rajappa S., Liu, Yi, Argenziano, Michael G., Banu, Matei A., Mladek, Ann C., West, Rita, Luu, Amanda, Quiñones-Hinojosa, Alfredo, Hambardzumyan, Dolores, Justilien, Verline, Leitges, Michael, Sarkaria, Jann N., Sims, Peter A., Canoll, Peter, Murray, Nicole R., Fields, Alan P., Rosenfeld, Steven S.
Publicado 2021

WSD-0922, a novel brain-penetrant inhibitor of epidermal growth factor receptor, promotes survival in glioblastoma mouse models

por Conage-Pough, Jason E, Stopka, Sylwia A, Oh, Ju-Hee, Mladek, Ann C, Burgenske, Danielle M, Regan, Michael S, Baquer, Gerard, Decker, Paul A, Carlson, Brett L, Bakken, Katrina K, Zhang, Jinqiang, Liu, Lily, Sun, Claire, Mu, Zhihua, Zhong, Wei, Tran, Nhan L, Elmquist, William F, Agar, Nathalie Y R, Sarkaria, Jann N, White, Forest M
Publicado 2023

Convection enhanced delivery of EGFR targeting antibody-drug conjugates Serclutamab talirine and Depatux-M in glioblastoma patient-derived xenografts

por Porath, Kendra A, Regan, Michael S, Griffith, Jessica I, Jain, Sonia, Stopka, Sylwia A, Burgenske, Danielle M, Bakken, Katrina K, Carlson, Brett L, Decker, Paul A, Vaubel, Rachael A, Dragojevic, Sonja, Mladek, Ann C, Connors, Margaret A, Hu, Zeng, He, Lihong, Kitange, Gaspar J, Gupta, Shiv K, Feldsien, Thomas M, Lefebvre, Didier R, Agar, Nathalie Y R, Eckel-Passow, Jeanette E, Reilly, Edward B, Elmquist, William F, Sarkaria, Jann N
Publicado 2022

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

por Randall, Elizabeth C., Emdal, Kristina B., Laramy, Janice K., Kim, Minjee, Roos, Alison, Calligaris, David, Regan, Michael S., Gupta, Shiv K., Mladek, Ann C., Carlson, Brett L., Johnson, Aaron J., Lu, Fa-Ke, Xie, X. Sunney, Joughin, Brian A., Reddy, Raven J., Peng, Sen, Abdelmoula, Walid M., Jackson, Pamela R., Kolluri, Aarti, Kellersberger, Katherine A., Agar, Jeffrey N., Lauffenburger, Douglas A., Swanson, Kristin R., Tran, Nhan L., Elmquist, William F., White, Forest M., Sarkaria, Jann N., Agar, Nathalie Y. R.
Publicado 2018