Mouse tumor susceptibility genes identify drug combinations for multiple myeloma

por Zhang, Shuling, DuBois, Wendy, Zhang, Ke, Simmons, John K., Hughitt, V. Keith, Gorjifard, Sayeh, Gaikwad, Snehal, Peat, Tyler J., Mock, Beverly A.
Publicado 2020

Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression

por Felsenstein, Kenneth M., Saunders, Lindsey B., Simmons, John K., Leon, Elena, Calabrese, David R., Zhang, Shuling, Michalowski, Aleksandra, Gareiss, Peter, Mock, Beverly A., Schneekloth, John S.
Publicado 2015

Characterization of clinically used oral antiseptics as quadruplex-binding ligands

por Calabrese, David R, Zlotkowski, Katherine, Alden, Stephanie, Hewitt, William M, Connelly, Colleen M, Wilson, Robert M, Gaikwad, Snehal, Chen, Lu, Guha, Rajarshi, Thomas, Craig J, Mock, Beverly A, Schneekloth, John S
Publicado 2018

Conventional Co-Housing Modulates Murine Gut Microbiota and Hematopoietic Gene Expression

por Chen, Jichun, Zhang, Shuling, Feng, Xingmin, Wu, Zhijie, Dubois, Wendy, Thovarai, Vishal, Ahluwalia, Sonia, Gao, Shouguo, Chen, Jinguo, Peat, Tyler, Sen, Shurjo K., Trinchieri, Giorgio, Young, Neal S., Mock, Beverly A.
Publicado 2020

A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma

por Gaikwad, Snehal M., Phyo, Zaw, Arteaga, Anaisa Quintanilla, Gorjifard, Sayeh, Calabrese, David R., Connors, Daniel, Huang, Jing, Michalowski, Aleksandra M., Zhang, Shuling, Liu, Zheng-Gang, Schneekloth, John S., Mock, Beverly A.
Publicado 2020

The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription

por Malik, Navdeep, Yan, Hualong, Moshkovich, Nellie, Palangat, Murali, Yang, Howard, Sanchez, Vanesa, Cai, Zhuo, Peat, Tyler J., Jiang, Shunlin, Liu, Chengyu, Lee, Maxwell, Mock, Beverly A., Yuspa, Stuart H., Larson, Daniel, Wakefield, Lalage M., Huang, Jing
Publicado 2019

mTOR inhibition overcomes RSK3-mediated resistance to BET inhibitors in small cell lung cancer

por Kumari, Anju, Gesumaria, Lisa, Liu, Yan-Jin, Hughitt, V. Keith, Zhang, Xiaohu, Ceribelli, Michele, Wilson, Kelli M., Klumpp-Thomas, Carleen, Chen, Lu, McKnight, Crystal, Itkin, Zina, Thomas, Craig J., Mock, Beverly A., Schrump, David S., Chen, Haobin
Publicado 2023

Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex

por Calabrese, David R., Chen, Xiang, Leon, Elena C., Gaikwad, Snehal M., Phyo, Zaw, Hewitt, William M., Alden, Stephanie, Hilimire, Thomas A., He, Fahu, Michalowski, Aleksandra M., Simmons, John K., Saunders, Lindsey B., Zhang, Shuling, Connors, Daniel, Walters, Kylie J., Mock, Beverly A., Schneekloth, John S.
Publicado 2018

mTOR intersects antibody-inducing signals from TACI in marginal zone B cells

por Sintes, Jordi, Gentile, Maurizio, Zhang, Shuling, Garcia-Carmona, Yolanda, Magri, Giuliana, Cassis, Linda, Segura-Garzón, Daniel, Ciociola, Alessandra, Grasset, Emilie K., Bascones, Sabrina, Comerma, Laura, Pybus, Marc, Lligé, David, Puga, Irene, Gutzeit, Cindy, He, Bing, DuBois, Wendy, Crespo, Marta, Pascual, Julio, Mensa, Anna, Aróstegui, Juan Ignacio, Juan, Manel, Yagüe, Jordi, Serrano, Sergi, Lloreta, Josep, Meffre, Eric, Hahne, Michael, Cunningham-Rundles, Charlotte, Mock, Beverly A., Cerutti, Andrea
Publicado 2017

Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice

por Xie, Kan, Fuchs, Helmut, Scifo, Enzo, Liu, Dan, Aziz, Ahmad, Aguilar-Pimentel, Juan Antonio, Amarie, Oana Veronica, Becker, Lore, da Silva-Buttkus, Patricia, Calzada-Wack, Julia, Cho, Yi-Li, Deng, Yushuang, Edwards, A. Cole, Garrett, Lillian, Georgopoulou, Christina, Gerlini, Raffaele, Hölter, Sabine M., Klein-Rodewald, Tanja, Kramer, Michael, Leuchtenberger, Stefanie, Lountzi, Dimitra, Mayer-Kuckuk, Phillip, Nover, Lena L., Oestereicher, Manuela A., Overkott, Clemens, Pearson, Brandon L., Rathkolb, Birgit, Rozman, Jan, Russ, Jenny, Schaaf, Kristina, Spielmann, Nadine, Sanz-Moreno, Adrián, Stoeger, Claudia, Treise, Irina, Bano, Daniele, Busch, Dirk H., Graw, Jochen, Klingenspor, Martin, Klopstock, Thomas, Mock, Beverly A., Salomoni, Paolo, Schmidt-Weber, Carsten, Weiergräber, Marco, Wolf, Eckhard, Wurst, Wolfgang, Gailus-Durner, Valérie, Breteler, Monique M. B., Hrabě de Angelis, Martin, Ehninger, Dan
Publicado 2022