Structure–Activity Relationship Studies of Pyrimidine-4-Carboxamides as Inhibitors of N-Acylphosphatidylethanolamine Phospholipase D

por Mock, Elliot D., Kotsogianni, Ioli, Driever, Wouter P. F., Fonseca, Carmen S., Vooijs, Jelle M., den Dulk, Hans, van Boeckel, Constant A. A., van der Stelt, Mario
Publicado 2020

Mitochondrial dysfunction and mitophagy defects in LRRK2-R1441C Parkinson’s disease models

por Williamson, Matthew G, Madureira, Marta, McGuinness, William, Heon-Roberts, Rachel, Mock, Elliot D, Naidoo, Kalina, Cramb, Kaitlyn M L, Caiazza, Maria-Claudia, Malpartida, Ana B, Lavelle, Martha, Savory, Katrina, Humble, Stewart W, Patterson, Ryan, Davis, John B, Connor-Robson, Natalie, Ryan, Brent J, Wade-Martins, Richard
Publicado 2023

Activity-Based Protein Profiling Identifies α-Ketoamides as Inhibitors for Phospholipase A2 Group XVI

por Zhou, Juan, Mock, Elliot D., Martella, Andrea, Kantae, Vasudev, Di, Xinyu, Burggraaff, Lindsey, Baggelaar, Marc P., Al-Ayed, Karol, Bakker, Alexander, Florea, Bogdan I., Grimm, Sebastian H., den Dulk, Hans, Li, Chun T., Mulder, Laura, Overkleeft, Herman S., Hankemeier, Thomas, van Westen, Gerard J. P., van der Stelt, Mario
Publicado 2019

Structure–Activity Relationship Studies of α-Ketoamides as Inhibitors of the Phospholipase A and Acyltransferase Enzyme Family

por Zhou, Juan, Mock, Elliot D., Al Ayed, Karol, Di, Xinyu, Kantae, Vasudev, Burggraaff, Lindsey, Stevens, Anna F., Martella, Andrea, Mohr, Florian, Jiang, Ming, van der Wel, Tom, Wendel, Tiemen J., Ofman, Tim P., Tran, Yvonne, de Koster, Nicky, van Westen, Gerard J.P., Hankemeier, Thomas, van der Stelt, Mario
Publicado 2020

Cannabinoid CB(2) receptor ligand profiling reveals biased signalling and off-target activity

por Soethoudt, Marjolein, Grether, Uwe, Fingerle, Jürgen, Grim, Travis W., Fezza, Filomena, de Petrocellis, Luciano, Ullmer, Christoph, Rothenhäusler, Benno, Perret, Camille, van Gils, Noortje, Finlay, David, MacDonald, Christa, Chicca, Andrea, Gens, Marianela Dalghi, Stuart, Jordyn, de Vries, Henk, Mastrangelo, Nicolina, Xia, Lizi, Alachouzos, Georgios, Baggelaar, Marc P., Martella, Andrea, Mock, Elliot D., Deng, Hui, Heitman, Laura H., Connor, Mark, Di Marzo, Vincenzo, Gertsch, Jürg, Lichtman, Aron H., Maccarrone, Mauro, Pacher, Pal, Glass, Michelle, van der Stelt, Mario
Publicado 2017