The Structural Biology of Galectin-Ligand Recognition: Current Advances in Modeling Tools, Protein Engineering, and Inhibitor Design

por Modenutti, Carlos P., Capurro, Juan I. Blanco, Di Lella, Santiago, Martí, Marcelo A.
Publicado 2019

First Whole-Genome Shotgun Sequence of a Promising Cellulase Secretor, Trichoderma koningiopsis Strain POS7

por Castrillo, María Lorena, Bich, Gustavo Ángel, Modenutti, Carlos, Turjanski, Adrián, Zapata, Pedro Darío, Villalba, Laura Lidia
Publicado 2017

Solvents to Fragments to Drugs: MD Applications in Drug Design

por Defelipe, Lucas A., Arcon, Juan Pablo, Modenutti, Carlos P., Marti, Marcelo A., Turjanski, Adrián G., Barril, Xavier
Publicado 2018

Origin and Evolution of Two Independently Duplicated Genes Encoding UDP- Glucose: Glycoprotein Glucosyltransferases in Caenorhabditis and Vertebrates

por Caraballo, Diego A., Buzzi, Lucila I., Modenutti, Carlos P., Acosta-Montalvo, Ana, Castro, Olga A., Rossi, María S.
Publicado 2019

VarQ: A Tool for the Structural and Functional Analysis of Human Protein Variants

por Radusky, Leandro, Modenutti, Carlos, Delgado, Javier, Bustamante, Juan P., Vishnopolska, Sebastian, Kiel, Christina, Serrano, Luis, Marti, Marcelo, Turjanski, Adrián
Publicado 2018

Longitudinal characterization of HIV-1 pol-gene in treatment-naïve men-who-have-sex-with-men from acute to chronic infection stages

por Cevallos, Cintia, Culasso, Andrés C.A., Modenutti, Carlos, Gun, Ana, Sued, Omar, Avila, María M., Flichman, Diego, Delpino, M. Victoria, Quarleri, Jorge
Publicado 2020

Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C-Type Lectin Langerin

por Zhang, Hengxi, Modenutti, Carlos, Nekkanti, Yelha Phani Kumar, Denis, Maxime, Bermejo, Iris A., Lefèbre, Jonathan, Che, Kateryna, Kim, Dongyoon, Kagelmacher, Marten, Kurzbach, Dennis, Nazaré, Marc, Rademacher, Christoph
Publicado 2022

Treatment with a New Peroxisome Proliferator-Activated Receptor Gamma Agonist, Pyridinecarboxylic Acid Derivative, Increases Angiogenesis and Reduces Inflammatory Mediators in the...

por Penas, Federico Nicolás, Carta, Davide, Dmytrenko, Ganna, Mirkin, Gerado A., Modenutti, Carlos Pablo, Cevey, Ágata Carolina, Rada, Maria Jimena, Ferlin, Maria Grazia, Sales, María Elena, Goren, Nora Beatriz
Publicado 2017

Rescue of secretion of a rare-disease associated mis-folded mutant glycoprotein in UGGT1 knock-out mammalian cells

por Tax, Gábor, Guay, Kevin P., Soldà, Tatiana, Hitchman, Charlie J., Hill, Johan C., Vasiljević, Snežana, Lia, Andrea, Modenutti, Carlos P., Straatman, Kees R., Santino, Angelo, Molinari, Maurizio, Zitzmann, Nicole, Hebert, Daniel N., Roversi, Pietro, Trerotola, Marco
Publicado 2023

From Genome to Drugs: New Approaches in Antimicrobial Discovery

por Serral, Federico, Castello, Florencia A., Sosa, Ezequiel J., Pardo, Agustín M., Palumbo, Miranda Clara, Modenutti, Carlos, Palomino, María Mercedes, Lazarowski, Alberto, Auzmendi, Jerónimo, Ramos, Pablo Ivan P., Nicolás, Marisa F., Turjanski, Adrián G., Martí, Marcelo A., Fernández Do Porto, Darío
Publicado 2021

Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase

por Modenutti, Carlos P., Blanco Capurro, Juan I., Ibba, Roberta, Alonzi, Dominic S., Song, Mauro N., Vasiljević, Snežana, Kumar, Abhinav, Chandran, Anu V., Tax, Gabor, Marti, Lucia, Hill, Johan C., Lia, Andrea, Hensen, Mario, Waksman, Thomas, Rushton, Jonathan, Rubichi, Simone, Santino, Angelo, Martí, Marcelo A., Zitzmann, Nicole, Roversi, Pietro
Publicado 2021

A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN

por Wawrzinek, Robert, Wamhoff, Eike-Christian, Lefebre, Jonathan, Rentzsch, Mareike, Bachem, Gunnar, Domeniconi, Gary, Schulze, Jessica, Fuchsberger, Felix F., Zhang, Hengxi, Modenutti, Carlos, Schnirch, Lennart, Marti, Marcelo A., Schwardt, Oliver, Bräutigam, Maria, Guberman, Mónica, Hauck, Dirk, Seeberger, Peter H., Seitz, Oliver, Titz, Alexander, Ernst, Beat, Rademacher, Christoph
Publicado 2021

First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival

por Guijarro, Maria V., Kellish, Patrick C., Dib, Peter E., Paciaroni, Nicholas G., Nawab, Akbar, Andring, Jacob, Kulemina, Lidia, Borrero, Nicholas V., Modenutti, Carlos, Feely, Michael, Nasri, Elham, Seifert, Robert P., Luo, Xiaoping, Bennett, Richard L., Shabashvili, Daniil, Licht, Jonathan D., McKenna, Robert, Roitberg, Adrian, Huigens, Robert W., Kaye, Frederic J., Zajac-Kaye, Maria
Publicado 2023

A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint

por Guay, Kevin P., Ibba, Roberta, Kiappes, J.L., Vasiljević, Snežana, Bonì, Francesco, De Benedictis, Maria, Zeni, Ilaria, Le Cornu, James D., Hensen, Mario, Chandran, Anu V., Kantsadi, Anastassia L., Caputo, Alessandro T., Blanco Capurro, Juan I., Bayo, Yusupha, Hill, Johan C., Hudson, Kieran, Lia, Andrea, Brun, Juliane, Withers, Stephen G., Martí, Marcelo, Biasini, Emiliano, Santino, Angelo, De Rosa, Matteo, Milani, Mario, Modenutti, Carlos P., Hebert, Daniel N., Zitzmann, Nicole, Roversi, Pietro
Publicado 2023