Comment on: “Retrospective Claims Analysis Indirectly Comparing Medication Adherence and Persistence Between Intravenous Biologics and Oral Small-Molecule Therapies in Inflammatory...

por Woolcott, John, Cappelleri, Joseph C., Sharma, Puza, Modesto, Irene
Publicado 2020

Identification of two tofacitinib subpopulations with different relative risk versus TNF inhibitors: an analysis of the open label, randomised controlled study ORAL Surveillance

por Kristensen, Lars Erik, Danese, Silvio, Yndestad, Arne, Wang, Cunshan, Nagy, Edward, Modesto, Irene, Rivas, Jose, Benda, Birgitta
Publicado 2023

Modeling of Treatment Outcomes with Tofacitinib Maintenance Therapy in Patients with Ulcerative Colitis: A Post Hoc Analysis of Data from the OCTAVE Clinical Program

por Chiorean, Michael, Daperno, Marco, Lees, Charlie W., Bonfanti, Gianluca, Soudis, Dimitrios, Modesto, Irene, Deuring, J. Jasper, Edwards, Roger A.
Publicado 2023

Worldwide post‐marketing safety surveillance experience with tofacitinib in ulcerative colitis

por Rubin, David T., Modesto, Irene, Vermeire, Séverine, Danese, Silvio, Ng, Siew C., Kwok, Kenneth K., Koram, Nana, Jones, Thomas V.
Publicado 2021

The Role of Portal Vein Thrombosis in the Clinical Course of Inflammatory Bowel Diseases: Report on Three Cases and Review of the Literature

por Sinagra, Emanuele, Aragona, Emma, Romano, Claudia, Maisano, Simonetta, Orlando, Ambrogio, Virdone, Roberto, Tesè, Lorenzo, Modesto, Irene, Criscuoli, Valeria, Cottone, Mario
Publicado 2012

Characteristics and Outcomes of IBD Patients with COVID-19 on Tofacitinib Therapy in the SECURE-IBD Registry

por Agrawal, Manasi, Brenner, Erica J, Zhang, Xian, Modesto, Irene, Woolcott, John, Ungaro, Ryan C, Colombel, Jean-Frederic, Kappelman, Michael D
Publicado 2020

Exposure‐Response Characterization of Tofacitinib Efficacy in Moderate to Severe Ulcerative Colitis: Results From Phase II and Phase III Induction and Maintenance Studies

por Mukherjee, Arnab, Tsuchiwata, Shinichi, Nicholas, Timothy, Cook, Jack A., Modesto, Irene, Su, Chinyu, D’Haens, Geert R., Sandborn, William J.
Publicado 2022

Modified Mayo score versus Mayo score for evaluation of treatment efficacy in patients with ulcerative colitis: data from the tofacitinib OCTAVE program

por Sandborn, William J., Sands, Bruce E., Vermeire, Séverine, Leung, Yvette, Guo, Xiang, Modesto, Irene, Su, Chinyu, Wang, Wenjin, Panés, Julian
Publicado 2022

Prediction of early clinical response in patients receiving tofacitinib in the OCTAVE Induction 1 and 2 studies

por Lees, Charlie W., Deuring, J. Jasper, Chiorean, Michael, Daperno, Marco, Bonfanti, Gianluca, Germino, Rebecca, Brown, Pritha Bhadra, Modesto, Irene, Edwards, Roger A.
Publicado 2021

Impact of Concomitant Corticosteroids on Tofacitinib Induction Efficacy and Infection Rates in Ulcerative Colitis

por Lichtenstein, Gary R., Cohen, Benjamin L., Salese, Leonardo, Modesto, Irene, Wang, Wenjin, Chan, Gary, Ahmed, Haytham Mohamed, Su, Chinyu, Peyrin-Biroulet, Laurent
Publicado 2023

Living with Ulcerative Colitis Study (LUCY) in England: a retrospective study evaluating healthcare resource utilisation and direct healthcare costs of postoperative care in ulcera...

por Brookes, Matthew J, Waller, John, Cappelleri, Joseph C, Modesto, Irene, DiBonaventura, Marco D, Bohm, Natalie, Mokgokong, Ruth, Massey, Olivia, Wood, Robert, Bargo, Danielle
Publicado 2020

Outcomes of Tofacitinib Dose Reduction in Patients with Ulcerative Colitis in Stable Remission from the Randomised RIVETING Trial

por Vermeire, Séverine, Su, Chinyu, Lawendy, Nervin, Kobayashi, Taku, Sandborn, William J, Rubin, David T, Modesto, Irene, Gardiner, Sean, Kulisek, Nicole, Zhang, Haiying, Wang, Wenjin, Panés, Julian
Publicado 2020

Efficacy and Safety of Tofacitinib Re-treatment for Ulcerative Colitis After Treatment Interruption: Results from the OCTAVE Clinical Trials

por Panés, Julian, Vermeire, Séverine, Dubinsky, Marla C, Loftus, Edward V, Lawendy, Nervin, Wang, Wenjin, Salese, Leonardo, Su, Chinyu, Modesto, Irene, Guo, Xiang, Colombel, Jean-Frederic
Publicado 2021

Venous thromboembolic events in the tofacitinib ulcerative colitis clinical development programme

por Sandborn, William J., Panés, Julian, Sands, Bruce E., Reinisch, Walter, Su, Chinyu, Lawendy, Nervin, Koram, Nana, Fan, Haiyun, Jones, Thomas V., Modesto, Irene, Quirk, Daniel, Danese, Silvio
Publicado 2019

Endoscopy and central reading in inflammatory bowel disease clinical trials: achievements, challenges and future developments

por Gottlieb, Klaus, Daperno, Marco, Usiskin, Keith, Sands, Bruce E, Ahmad, Harris, Howden, Colin W, Karnes, William, Oh, Young S, Modesto, Irene, Marano, Colleen, Stidham, Ryan William, Reinisch, Walter
Publicado 2021

Extraintestinal manifestations at baseline, and the effect of tofacitinib, in patients with moderate to severe ulcerative colitis

por Rubin, David T., Reinisch, Walter, Greuter, Thomas, Kotze, Paulo G., Pinheiro, Marcia, Mundayat, Rajiv, Maller, Eric, Fellmann, Marc, Lawendy, Nervin, Modesto, Irene, Vavricka, Stephan R., Lichtenstein, Gary R.
Publicado 2021

Long-term Risk of Herpes Zoster Infection in Patients With Ulcerative Colitis Receiving Tofacitinib

por Winthrop, Kevin L, Vermeire, Séverine, Long, Millie D, Panés, Julian, Ng, Siew C, Kulisek, Nicole, Mundayat, Rajiv, Lawendy, Nervin, Vranic, Ivana, Modesto, Irene, Su, Chinyu, Melmed, Gil Y
Publicado 2022

Tofacitinib Treatment Safety in Moderate to Severe Ulcerative Colitis: Comparison of Observational Population Cohort Data From the IBM MarketScan® Administrative Claims Database Wi...

por Curtis, Jeffrey R, Regueiro, Miguel, Yun, Huifeng, Su, Chinyu, DiBonaventura, Marco, Lawendy, Nervin, Nduaka, Chudy I, Koram, Nana, Cappelleri, Joseph C, Chan, Gary, Modesto, Irene, Lichtenstein, Gary R
Publicado 2020

Tofacitinib for the Treatment of Ulcerative Colitis: An Integrated Summary of up to 7.8 Years of Safety Data from the Global Clinical Programme

por Sandborn, William J, D’Haens, Geert R, Sands, Bruce E, Panaccione, Remo, Ng, Siew C, Lawendy, Nervin, Kulisek, Nicole, Modesto, Irene, Guo, Xiang, Mundayat, Rajiv, Su, Chinyu, Vranic, Ivana, Panés, Julian
Publicado 2022

Safety and efficacy of tofacitinib for treatment of ulcerative colitis: final analysis of OCTAVE Open, an open‐label, long‐term extension study with up to 7.0 years of treatment...

por Sandborn, William J., Lawendy, Nervin, Danese, Silvio, Su, Chinyu, Loftus, Edward V., Hart, Ailsa, Dotan, Iris, Damião, Adérson O. M. C., Judd, Donna T., Guo, Xiang, Modesto, Irene, Wang, Wenjin, Panés, Julian
Publicado 2021