In vaginal fluid, bacteria associated with bacterial vaginosis can be suppressed with lactic acid but not hydrogen peroxide

por O'Hanlon, Deirdre E, Moench, Thomas R, Cone, Richard A
Publicado 2011

Vaginal pH and Microbicidal Lactic Acid When Lactobacilli Dominate the Microbiota

por O’Hanlon, Deirdre E., Moench, Thomas R., Cone, Richard A.
Publicado 2013

Vaginal pH measured in vivo: lactobacilli determine pH and lactic acid concentration

por O’Hanlon, Deirdre Elizabeth, Come, Richard A., Moench, Thomas R.
Publicado 2019

Cervicovaginal fluid and semen block the microbicidal activity of hydrogen peroxide produced by vaginal lactobacilli

por O'Hanlon, Deirdre E, Lanier, Blair R, Moench, Thomas R, Cone, Richard A
Publicado 2010

Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse

por Moench, Thomas R, Mumper, Russell J, Hoen, Timothy E, Sun, Mianmian, Cone, Richard A
Publicado 2010

Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission

por Cone, Richard A, Hoen, Timothy, Wong, XiXi, Abusuwwa, Raed, Anderson, Deborah J, Moench, Thomas R
Publicado 2006

Biomarkers and biometric measures of adherence to use of ARV-based vaginal rings

por Stalter, Randy M, Moench, Thomas R, MacQueen, Kathleen M, Tolley, Elizabeth E, Owen, Derek H
Publicado 2016

An acceptability and safety study of the Duet(® )cervical barrier and gel delivery system in Zimbabwe

por Montgomery, Elizabeth T, Woodsong, Cynthia, Musara, Petina, Cheng, Helen, Chipato, Tsungai, Moench, Thomas R, Spielberg, Freya, van der Straten, Ariane
Publicado 2010

Low pH immobilizes and kills human leukocytes and prevents transmission of cell-associated HIV in a mouse model

por Olmsted, Stuart S, Khanna, Kristen V, Ng, Erina M, Whitten, Steven T, Johnson, Owen N, Markham, Richard B, Cone, Richard A, Moench, Thomas R
Publicado 2005

Engineering monoclonal antibody-based contraception and multipurpose prevention technologies(†)

por Anderson, Deborah J, Politch, Joseph A, Cone, Richard A, Zeitlin, Larry, Lai, Samuel K, Santangelo, Philip J, Moench, Thomas R, Whaley, Kevin J
Publicado 2020

LALAPG variant of the Human Contraception Antibody (HCA) reduces Fc-mediated effector functions while maintaining sperm agglutination activity

por Mausser, Emilie, Nador, Ellena, Politch, Joseph A., Pauly, Michael R., Marathe, Jai G., Moench, Thomas R., Zeitlin, Larry, Whaley, Kevin J., Anderson, Deborah J.
Publicado 2023

Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid

por Tyssen, David, Wang, Ying-Ying, Hayward, Joshua A., Agius, Paul A., DeLong, Kevin, Aldunate, Muriel, Ravel, Jacques, Moench, Thomas R., Cone, Richard A., Tachedjian, Gilda
Publicado 2018

SPL7013 Gel (VivaGel®) Retains Potent HIV-1 and HSV-2 Inhibitory Activity following Vaginal Administration in Humans

por Price, Clare F., Tyssen, David, Sonza, Secondo, Davie, Ashley, Evans, Sonya, Lewis, Gareth R., Xia, Shirley, Spelman, Tim, Hodsman, Peter, Moench, Thomas R., Humberstone, Andrew, Paull, Jeremy R.A., Tachedjian, Gilda
Publicado 2011

Production and characterization of a human antisperm monoclonal antibody against CD52g for topical contraception in women

por Baldeon-Vaca, Gabriela, Marathe, Jai G., Politch, Joseph A., Mausser, Emilie, Pudney, Jeffrey, Doud, James, Nador, Ellena, Zeitlin, Larry, Pauly, Michael, Moench, Thomas R., Brennan, Miles, Whaley, Kevin J., Anderson, Deborah J.
Publicado 2021

The cervicovaginal mucus barrier to HIV-1 is diminished in bacterial vaginosis

por Hoang, Thuy, Toler, Emily, DeLong, Kevin, Mafunda, Nomfuneko A., Bloom, Seth M., Zierden, Hannah C., Moench, Thomas R., Coleman, Jenell S., Hanes, Justin, Kwon, Douglas S., Lai, Samuel K., Cone, Richard A., Ensign, Laura M.
Publicado 2020

Safety, acceptability, and pharmacokinetics of a monoclonal antibody-based vaginal multipurpose prevention film (MB66): A Phase I randomized trial

por Politch, Joseph A., Cu-Uvin, Susan, Moench, Thomas R., Tashima, Karen T., Marathe, Jai G., Guthrie, Kate M., Cabral, Howard, Nyhuis, Tara, Brennan, Miles, Zeitlin, Larry, Spiegel, Hans M. L., Mayer, Kenneth H., Whaley, Kevin J., Anderson, Deborah J.
Publicado 2021

Hexavalent sperm-binding IgG antibody released from vaginal film for development of potent on-demand nonhormonal female contraception

por Shrestha, Bhawana, Vincent, Kathleen, Schaefer, Alison, Zhu, Yong, Vargas, Gracie, Motamedi, Massoud, Swope, Kelsi, Morton, Josh, Simpson, Carrie, Pham, Henry, Brennan, Miles B., Pauly, Michael H., Zeitlin, Larry, Bratcher, Barry, Whaley, Kevin J., Moench, Thomas R., Lai, Samuel K.
Publicado 2021