Unraveling the complexity of therapeutic drug monitoring for monoclonal antibody therapies to individualize dose in oncology

por Chatelut, Etienne, Hendrikx, Jeroen J. M. A., Martin, Jennifer, Ciccolini, Joseph, Moes, Dirk Jan A. R.
Publicado 2021

The Course of AαVal541 as a Proteinase 3 Specific Neo-Epitope after Alpha-1-Antitrypsin Augmentation in Severe Deficient Patients

por Schouten, Iris G. M., Mumford, Richard A., Moes, Dirk Jan A. R., Hiemstra, Pieter S., Stolk, Jan
Publicado 2021

Clinical Pharmacokinetics and Pharmacodynamics of Immune Checkpoint Inhibitors

por Centanni, Maddalena, Moes, Dirk Jan A. R., Trocóniz, Iñaki F., Ciccolini, Joseph, van Hasselt, J. G. Coen
Publicado 2019

A Review of Mathematical Models for Tumor Dynamics and Treatment Resistance Evolution of Solid Tumors

por Yin, Anyue, Moes, Dirk Jan A.R., van Hasselt, Johan G.C., Swen, Jesse J., Guchelaar, Henk‐Jan
Publicado 2019

The Clinical Impact of the C(0)/D Ratio and the CYP3A5 Genotype on Outcome in Tacrolimus Treated Kidney Transplant Recipients

por van Gelder, Teun, Meziyerh, Soufian, Swen, Jesse J., de Vries, Aiko P. J., Moes, Dirk Jan A. R.
Publicado 2020

Anti-cancer treatment schedule optimization based on tumor dynamics modelling incorporating evolving resistance

por Yin, Anyue, van Hasselt, Johan G. C., Guchelaar, Henk-Jan, Friberg, Lena E., Moes, Dirk Jan A. R.
Publicado 2022

Publisher Correction: Anti-cancer treatment schedule optimization based on tumor dynamics modelling incorporating evolving resistance

por Yin, Anyue, van Hasselt, Johan G. C., Guchelaar, Henk-Jan, Friberg, Lena E., Moes, Dirk Jan A. R.
Publicado 2022

Population pharmacokinetics and genetics of oral meltdose tacrolimus (Envarsus) in stable adult liver transplant recipients

por Martial, Lisa C., Biewenga, Maaike, Ruijter, Bastian N., Keizer, Ron, Swen, Jesse J., van Hoek, Bart, Moes, Dirk Jan A. R.
Publicado 2021

Exposure–response analysis of endoxifen serum concentrations in early-breast cancer

por Sanchez-Spitman, Anabel Beatriz, Moes, Dirk-Jan A. R., Swen, Jesse J., Dezentjé, Vincent O., Lambrechts, Diether, Neven, Patrick, Gelderblom, Hans, Guchelaar, Henk-Jan
Publicado 2020

Feasibility of Community Pharmacist-Initiated and Point-of-Care CYP2C19 Genotype-Guided De-Escalation of Oral P2Y12 Inhibitors

por Levens, Amar D., den Haan, Melina C., Jukema, J. Wouter, Heringa, Mette, van den Hout, Wilbert B., Moes, Dirk Jan A. R., Swen, Jesse J.
Publicado 2023

Therapeutic Drug Monitoring of Conditioning Agents in Pediatric Allogeneic Stem Cell Transplantation; Where do We Stand?

por van der Stoep, M. Y. Eileen C., Oostenbrink, Lisa V. E., Bredius, Robbert G. M., Moes, Dirk Jan A. R., Guchelaar, Henk-Jan, Zwaveling, Juliette, Lankester, Arjan C.
Publicado 2022

Physiologically based pharmacokinetic modeling of tacrolimus for food–drug and CYP3A drug–drug–gene interaction predictions

por Loer, Helena Leonie Hanae, Feick, Denise, Rüdesheim, Simeon, Selzer, Dominik, Schwab, Matthias, Teutonico, Donato, Frechen, Sebastian, van der Lee, Maaike, Moes, Dirk Jan A. R., Swen, Jesse J., Lehr, Thorsten
Publicado 2023

Monitoring of Ex Vivo Cyclosporin a Activity in Healthy Volunteers Using T Cell Function Assays in Relation to Whole Blood and Cellular Pharmacokinetics

por in ’t Veld, Aliede E., Jansen, Manon A. A., Huisman, Bertine W., Schoonakker, Mascha, de Kam, Marieke L., Moes, Dirk Jan A. R., van Poelgeest, Mariëtte I. E., Burggraaf, Jacobus, Moerland, Matthijs
Publicado 2022

Immune Monitoring of Mycophenolate Mofetil Activity in Healthy Volunteers Using Ex Vivo T Cell Function Assays

por in ’t Veld, Aliede E., Jansen, Manon A. A., de Kam, Marieke L., Yavuz, Yalҫin, Moes, Dirk Jan A. R., Oudhoff, Kathalijne A., van Poelgeest, Mariette I. E., Burggraaf, Jacobus, Moerland, Matthijs
Publicado 2023

Model-Informed Precision Dosing of Everolimus: External Validation in Adult Renal Transplant Recipients

por Zwart, Tom C., Moes, Dirk Jan A. R., van der Boog, Paul J. M., van Erp, Nielka P., de Fijter, Johan W., Guchelaar, Henk-Jan, Keizer, Ron J., ter Heine, Rob
Publicado 2020

Volumetric microsampling for simultaneous remote immunosuppressant and kidney function monitoring in outpatient kidney transplant recipients

por Zwart, Tom C., Metscher, Erik, van der Boog, Paul J. M., Swen, Jesse J., de Fijter, Johan W., Guchelaar, Henk‐Jan, de Vries, Aiko P. J., Moes, Dirk Jan A. R.
Publicado 2022

The Cyclophilin-Dependent Calcineurin Inhibitor Voclosporin Inhibits SARS-CoV-2 Replication in Cell Culture

por Ogando, Natacha S., Metscher, Erik, Moes, Dirk Jan A. R., Arends, Eline J., Tas, Ali, Cross, Jennifer, Snijder, Eric J., Teng, Y. K. Onno, de Vries, Aiko P. J., van Hemert, Martijn J.
Publicado 2022

Ustekinumab Trough Concentrations Are Associated with Biochemical Outcomes in Patients with Crohn’s Disease

por Straatmijer, Tessa, Biemans, Vince B. C., Moes, Dirk Jan A. R., Hoentjen, Frank, ter Heine, Rob, Maljaars, P. W. Jeroen, Theeuwen, Rosaline, Pierik, Marieke, Duijvestein, Marjolijn, van der Meulen-de Jong, Andrea E.
Publicado 2023

Physiologically‐based pharmacokinetic modeling of quinidine to establish a CYP3A4, P‐gp, and CYP2D6 drug–drug–gene interaction network

por Feick, Denise, Rüdesheim, Simeon, Marok, Fatima Zahra, Selzer, Dominik, Loer, Helena Leonie Hanae, Teutonico, Donato, Frechen, Sebastian, van der Lee, Maaike, Moes, Dirk Jan A. R., Swen, Jesse J., Schwab, Matthias, Lehr, Thorsten
Publicado 2023

Exposure–response analyses of cabozantinib in patients with metastatic renal cell cancer

por Krens, Stefanie D., van Erp, Nielka P., Groenland, Stefanie L., Moes, Dirk Jan A. R., Mulder, Sasja F., Desar, Ingrid M. E., van der Hulle, Tom, Steeghs, Neeltje, van Herpen, Carla M. L.
Publicado 2022