N-Acetylaspartate reductions in brain injury: impact on post-injury neuroenergetics, lipid synthesis, and protein acetylation

por Moffett, John R., Arun, Peethambaran, Ariyannur, Prasanth S., Namboodiri, Aryan M. A.
Publicado 2013

The end of the road for the tryptophan depletion concept in pregnancy and infection

por Badawy, Abdulla A.-B., Namboodiri, Aryan M.A., Moffett, John R.
Publicado 2016

Acetate Revisited: A Key Biomolecule at the Nexus of Metabolism, Epigenetics and Oncogenesis—Part 1: Acetyl-CoA, Acetogenesis and Acyl-CoA Short-Chain Synthetases

por Moffett, John R., Puthillathu, Narayanan, Vengilote, Ranjini, Jaworski, Diane M., Namboodiri, Aryan M.
Publicado 2020

Acetate Revisited: A Key Biomolecule at the Nexus of Metabolism, Epigenetics, and Oncogenesis – Part 2: Acetate and ACSS2 in Health and Disease

por Moffett, John R., Puthillathu, Narayanan, Vengilote, Ranjini, Jaworski, Diane M., Namboodiri, Aryan M.
Publicado 2020

NAAG peptidase inhibition in the periaqueductal gray and rostral ventromedial medulla reduces flinching in the formalin model of inflammation

por Yamada, Toshihiko, Zuo, Daiying, Yamamoto, Tatsuo, Olszewski, Rafal T, Bzdega, Tomasz, Moffett, John R, Neale, Joseph H
Publicado 2012

A role for the locus coeruleus in the analgesic efficacy of N-acetylaspartylglutamate peptidase (GCPII) inhibitors ZJ43 and 2-PMPA

por Nonaka, Takahiro, Yamada, Toshihiko, Ishimura, Tatsuhiro, Zuo, Daiying, Moffett, John R, Neale, Joseph H, Yamamoto, Tatsuo
Publicado 2017

Quinolinate as a Marker for Kynurenine Metabolite Formation and the Unresolved Question of NAD(+) Synthesis During Inflammation and Infection

por Moffett, John R., Arun, Peethambaran, Puthillathu, Narayanan, Vengilote, Ranjini, Ives, John A., Badawy, Abdulla A-B, Namboodiri, Aryan M.
Publicado 2020

Increasing N-acetylaspartate in the Brain during Postnatal Myelination Does Not Cause the CNS Pathologies of Canavan Disease

por Appu, Abhilash P., Moffett, John R., Arun, Peethambaran, Moran, Sean, Nambiar, Vikram, Krishnan, Jishnu K. S., Puthillathu, Narayanan, Namboodiri, Aryan M. A.
Publicado 2017

Acetate Supplementation Induces Growth Arrest of NG2/PDGFRα-Positive Oligodendroglioma-Derived Tumor-Initiating Cells

por Long, Patrick M., Tighe, Scott W., Driscoll, Heather E., Moffett, John R., Namboodiri, Aryan M. A., Viapiano, Mariano S., Lawler, Sean E., Jaworski, Diane M.
Publicado 2013

Acss2 Deletion Reveals Functional Versatility via Tissue-Specific Roles in Transcriptional Regulation

por Vasudevan, Narayanan Puthillathu, Soni, Dharmendra K., Moffett, John R., Krishnan, Jishnu K. S., Appu, Abhilash P., Ghoshal, Sarani, Arun, Peethambaran, Denu, John M., Flagg, Thomas P., Biswas, Roopa, Namboodiri, Aryan M.
Publicado 2023

Metabolic acetate therapy improves phenotype in the tremor rat model of Canavan disease

por Arun, Peethambaran, Madhavarao, Chikkathur N., Moffett, John R., Hamilton, Kristen, Grunberg, Neil E., Ariyannur, Prasanth S., Gahl, William A., Anikster, Yair, Mog, Steven, Hallows, William C., Denu, John M., Namboodiri, Aryan M. A.
Publicado 2010