Defining baseline epigenetic landscapes in the rat liver

por Thomson, John P, Ottaviano, Raffaele, Buesen, Roland, Moggs, Jonathan G, Schwarz, Michael, Meehan, Richard R
Publicado 2017

The Need to Decide If All Estrogens Are Intrinsically Similar

por Moggs, Jonathan G., Ashby, John, Tinwell, Helen, Lim, Fei Ling, Moore, David J., Kimber, Ian, Orphanides, George
Publicado 2004

Computational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion

por Luisier, Raphaëlle, Unterberger, Elif B., Goodman, Jay I., Schwarz, Michael, Moggs, Jonathan, Terranova, Rémi, van Nimwegen, Erik
Publicado 2014

Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver

por Thomson, John P., Hunter, Jennifer M., Lempiäinen, Harri, Müller, Arne, Terranova, Rémi, Moggs, Jonathan G., Meehan, Richard R.
Publicado 2013

Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques

por Thomson, John P., Hunter, Jennifer M., Nestor, Colm E., Dunican, Donncha S., Terranova, Rémi, Moggs, Jonathan G., Meehan, Richard R.
Publicado 2013

Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques

por Thomson, John P., Hunter, Jennifer M., Nestor, Colm E., Dunican, Donncha S., Terranova, Rémi, Moggs, Jonathan G., Meehan, Richard R.
Publicado 2014

Constitutive androstane receptor 1 is constitutively bound to chromatin and ‘primed’ for transactivation in hepatocytes

por McMahon, Michael, Ding, Shaohong, Jimenez, Lourdes Acosta, Terranova, Remi, Gerard, Marie-Apolline, Vitobello, Antonio, Moggs, Jonathan, Henderson, Colin J., Wolf, C. Roland
Publicado 2019

Unaltered hepatic wound healing response in male rats with ancestral liver injury

por Beil, Johanna, Perner, Juliane, Pfaller, Lena, Gérard, Marie-Apolline, Piaia, Alessandro, Doelemeyer, Arno, Wasserkrug Naor, Adi, Martin, Lori, Piequet, Aline, Dubost, Valérie, Chibout, Salah-Dine, Moggs, Jonathan, Terranova, Rémi
Publicado 2023

Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome

por Thomson, John P, Lempiäinen, Harri, Hackett, Jamie A, Nestor, Colm E, Müller, Arne, Bolognani, Federico, Oakeley, Edward J, Schübeler, Dirk, Terranova, Rémi, Reinhardt, Diana, Moggs, Jonathan G, Meehan, Richard R
Publicado 2012

Reciprocal changes in DNA methylation and hydroxymethylation and a broad repressive epigenetic switch characterize FMR1 transcriptional silencing in fragile X syndrome

por Brasa, Sarah, Mueller, Arne, Jacquemont, Sébastien, Hahne, Florian, Rozenberg, Izabela, Peters, Thomas, He, Yunsheng, McCormack, Christine, Gasparini, Fabrizio, Chibout, Salah-Dine, Grenet, Olivier, Moggs, Jonathan, Gomez-Mancilla, Baltazar, Terranova, Rémi
Publicado 2016

Phenotypic Anchoring of Gene Expression Changes during Estrogen-Induced Uterine Growth

por Moggs, Jonathan G., Tinwell, Helen, Spurway, Tracey, Chang, Hur-Song, Pate, Ian, Lim, Fei Ling, Moore, David J., Soames, Anthony, Stuckey, Ruth, Currie, Richard, Zhu, Tong, Kimber, Ian, Ashby, John, Orphanides, George
Publicado 2004

Phenobarbital Mediates an Epigenetic Switch at the Constitutive Androstane Receptor (CAR) Target Gene Cyp2b10 in the Liver of B6C3F1 Mice

por Lempiäinen, Harri, Müller, Arne, Brasa, Sarah, Teo, Soon-Siong, Roloff, Tim-Christoph, Morawiec, Laurent, Zamurovic, Natasa, Vicart, Axel, Funhoff, Enrico, Couttet, Philippe, Schübeler, Dirk, Grenet, Olivier, Marlowe, Jennifer, Moggs, Jonathan, Terranova, Rémi
Publicado 2011

Perturbation of microRNAs in Rat Heart during Chronic Doxorubicin Treatment

por Vacchi-Suzzi, Caterina, Bauer, Yasmina, Berridge, Brian R., Bongiovanni, Sandrine, Gerrish, Kevin, Hamadeh, Hisham K., Letzkus, Martin, Lyon, Jonathan, Moggs, Jonathan, Paules, Richard S., Pognan, François, Staedtler, Frank, Vidgeon-Hart, Martin P., Grenet, Olivier, Couttet, Philippe
Publicado 2012

Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital

por Antoine, Daniel J, Dear, James W, Lewis, Philip Starkey, Platt, Vivien, Coyle, Judy, Masson, Moyra, Thanacoody, Ruben H, Gray, Alasdair J, Webb, David J, Moggs, Jonathan G, Bateman, D Nicholas, Goldring, Christopher E, Park, B Kevin
Publicado 2013

Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion

por Vitobello, Antonio, Perner, Juliane, Beil, Johanna, Zhu, Jiang, Del Río-Espínola, Alberto, Morawiec, Laurent, Westphal, Magdalena, Dubost, Valérie, Altorfer, Marc, Naumann, Ulrike, Mueller, Arne, Kapur, Karen, Borowsky, Mark, Henderson, Colin, Wolf, C Roland, Schwarz, Michael, Moggs, Jonathan, Terranova, Rémi
Publicado 2019

Heart Structure-Specific Transcriptomic Atlas Reveals Conserved microRNA-mRNA Interactions

por Vacchi-Suzzi, Caterina, Hahne, Florian, Scheubel, Philippe, Marcellin, Magali, Dubost, Valerie, Westphal, Magdalena, Boeglen, Catherine, Büchmann-Møller, Stine, Cheung, Ming Sin, Cordier, André, De Benedetto, Christopher, Deurinck, Mark, Frei, Moritz, Moulin, Pierre, Oakeley, Edward, Grenet, Olivier, Grevot, Armelle, Stull, Robert, Theil, Diethilde, Moggs, Jonathan G., Marrer, Estelle, Couttet, Philippe
Publicado 2013

The genetic consequences of dog breed formation—Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier...

por Axelsson, Erik, Ljungvall, Ingrid, Bhoumik, Priyasma, Conn, Laura Bas, Muren, Eva, Ohlsson, Åsa, Olsen, Lisbeth Høier, Engdahl, Karolina, Hagman, Ragnvi, Hanson, Jeanette, Kryvokhyzha, Dmytro, Pettersson, Mats, Grenet, Olivier, Moggs, Jonathan, Del Rio-Espinola, Alberto, Epe, Christian, Taillon, Bruce, Tawari, Nilesh, Mane, Shrinivas, Hawkins, Troy, Hedhammar, Åke, Gruet, Philippe, Häggström, Jens, Lindblad-Toh, Kerstin
Publicado 2021

Correction: The genetic consequences of dog breed formation—Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease...

por Axelsson, Erik, Ljungvall, Ingrid, Bhoumik, Priyasma, Conn, Laura Bas, Muren, Eva, Ohlsson, Åsa, Olsen, Lisbeth Høier, Engdahl, Karolina, Hagman, Ragnvi, Hanson, Jeanette, Kryvokhyzha, Dmytro, Pettersson, Mats, Grenet, Olivier, Moggs, Jonathan, Rio-Espinola, Alberto Del, Epe, Christian, Taillon, Bruce, Tawari, Nilesh, Mane, Shrinivas, Hawkins, Troy, Hedhammar, Åke, Gruet, Philippe, Häggström, Jens, Lindblad-Toh, Kerstin
Publicado 2022

Challenges and approaches for the development of safer immunomodulatory biologics

por Sathish, Jean G., Sethu, Swaminathan, Bielsky, Marie-Christine, de Haan, Lolke, French, Neil S., Govindappa, Karthik, Green, James, Griffiths, Christopher E. M., Holgate, Stephen, Jones, David, Kimber, Ian, Moggs, Jonathan, Naisbitt, Dean J., Pirmohamed, Munir, Reichmann, Gabriele, Sims, Jennifer, Subramanyam, Meena, Todd, Marque D., Van Der Laan, Jan Willem, Weaver, Richard J., Park, B. Kevin
Publicado 2013