KRAS-Mutant Lung Cancer: Targeting Molecular and Immunologic Pathways, Therapeutic Advantages and Restrictions

por Karimi, Nastaran, Moghaddam, Seyed Javad
Publicado 2023

Cell Type-Specific Roles of STAT3 Signaling in the Pathogenesis and Progression of K-ras Mutant Lung Adenocarcinoma

por Clowers, Michael J., Moghaddam, Seyed Javad
Publicado 2022

Nontypeable Haemophilus influenzae in chronic obstructive pulmonary disease and lung cancer

por Moghaddam, Seyed Javad, Ochoa, Cesar E, Sethi, Sanjay, Dickey, Burton F
Publicado 2011

Understanding the Complexity of the Tumor Microenvironment in K-ras Mutant Lung Cancer: Finding an Alternative Path to Prevention and Treatment

por Deng, Shanshan, Clowers, Michael J., Velasco, Walter V., Ramos-Castaneda, Marco, Moghaddam, Seyed Javad
Publicado 2020

Enhancement of lung tumorigenesis in a Gprc5a Knockout mouse by chronic extrinsic airway inflammation

por Barta, Peter, Van Pelt, Carolyn, Men, Taoyan, Dickey, Burton F, Lotan, Reuben, Moghaddam, Seyed Javad
Publicado 2012

Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase

por Gong, Lei, Cumpian, Amber M, Caetano, Mauricio S, Ochoa, Cesar E, De la Garza, Maria Miguelina, Lapid, Daniel J, Mirabolfathinejad, Seyedeh Golsar, Dickey, Burton F, Zhou, Qinghua, Moghaddam, Seyed Javad
Publicado 2013

STAT3 restrains RANK- and TLR4-mediated signaling by suppressing expression of the E2 ubiquitin ligase Ubc13

por Zhang, Huiyuan, Hu, Hongbo, Greeley, Nathaniel, Jin, Jin, Matthews, Allison J., Ohashi, Erika, Caetano, Mauricio S., Li, Haiyan S., Wu, Xuefeng, Mandal, Pijus K., McMurray, John S., Moghaddam, Seyed Javad, Sun, Shao-Cong, Watowich, Stephanie S.
Publicado 2014

OBIF: an omics-based interaction framework to reveal molecular drivers of synergy

por Pantaleón García, Jezreel, Kulkarni, Vikram V, Reese, Tanner C, Wali, Shradha, Wase, Saima J, Zhang, Jiexin, Singh, Ratnakar, Caetano, Mauricio S, Kadara, Humam, Moghaddam, Seyed Javad, Johnson, Faye M, Wang, Jing, Wang, Yongxing, Evans, Scott E
Publicado 2022

Cigarette smoke exposure accelerates AML progression in FLT3-ITD models

por Figueroa, Mary, Ma, Huaxian, Alfayez, Mansour, Morales-Mantilla, Daniel Enrique, Wang, Fei, Lu, Yue, Estecio, Marcos R., King, Katherine Y., Kleinerman, Eugenie, Moghaddam, Seyed Javad, Daver, Naval, Andreeff, Michael, Konopleva, Marina, DiNardo, Courtney, Chandra, Joya
Publicado 2023

Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes

por Finnicum, Casey T., Rahal, Zahraa, Hassane, Maya, Treekitkarnmongkol, Warapen, Sinjab, Ansam, Morris, Rhiannon, Liu, Yuejiang, Tang, Elizabeth L., Viet, Sarah, Petersen, Jason L., Lorenzi, Philip L., Tan, Lin, Petrosino, Joseph, Hoffman, Kristi L., Fujimoto, Junya, Moghaddam, Seyed Javad, Kadara, Humam
Publicado 2022

Toll-like receptors 2, 4, and 9 modulate promoting effect of COPD-like airway inflammation on K-ras-driven lung cancer through activation of the MyD88/NF-ĸB pathway in the airway e...

por Velasco, Walter V., Khosravi, Nasim, Castro-Pando, Susana, Torres-Garza, Nelly, Grimaldo, Maria T., Krishna, Avantika, Clowers, Michael J., Umer, Misha, Tariq Amir, Sabah, Del Bosque, Diana, Daliri, Soudabeh, De La Garza, Maria Miguelina, Ramos-Castaneda, Marco, Evans, Scott E., Moghaddam, Seyed Javad
Publicado 2023

Targeting IL-1β as an immunopreventive and therapeutic modality for K-ras–mutant lung cancer

por Yuan, Bo, Clowers, Michael J., Velasco, Walter V., Peng, Stephen, Peng, Qian, Shi, Yewen, Ramos-Castaneda, Marco, Zarghooni, Melody, Yang, Shuanying, Babcock, Rachel L., Chang, Seon Hee, Heymach, John V., Zhang, Jianjun, Ostrin, Edwin J., Watowich, Stephanie S., Kadara, Humam, Moghaddam, Seyed Javad
Publicado 2022

COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation

por De la Garza, Maria Miguelina, Cumpian, Amber M., Daliri, Soudabeh, Castro-Pando, Susana, Umer, Misha, Gong, Lei, Khosravi, Nasim, Caetano, Mauricio S., Ramos-Castañeda, Marco, Flores, Alejandra Garza, Beltran, Evelyn C., Tran, Hai T., Tuvim, Michael J., Ostrin, Edwin J., Dickey, Burton F., Evans, Christopher M., Moghaddam, Seyed Javad
Publicado 2018

Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer

por Caetano, Mauricio S., Hassane, Maya, Van, Hieu T., Bugarin, Emmanuel, Cumpian, Amber M., McDowell, Christina L., Cavazos, Carolina Gonzalez, Zhang, Huiyuan, Deng, Shanshan, Diao, Lixia, Wang, Jing, Evans, Scott E., Behrens, Carmen, Wistuba, Ignacio I., Fuqua, Susan A. W., Lin, Huang, Stabile, Laura P., Watowich, Stephanie S., Kadara, Humam, Moghaddam, Seyed Javad
Publicado 2018

Single-Cell Expression Landscape of SARS-CoV-2 Receptor ACE2 and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients

por Han, Guangchun, Sinjab, Ansam, Hara, Kieko, Treekitkarnmongkol, Warapen, Brennan, Patrick, Chang, Kyle, Bogatenkova, Elena, Sanchez-Espiridion, Beatriz, Behrens, Carmen, Solis, Luisa M., Gao, Boning, Girard, Luc, Zhang, Jianjun, Sepesi, Boris, Cascone, Tina, Byers, Lauren A., Gibbons, Don L., Chen, Jichao, Moghaddam, Seyed Javad, Ostrin, Edwin J., Scheet, Paul, Fujimoto, Junya, Shay, Jerry, Heymach, John V., Minna, John D., Dubinett, Steven, Wistuba, Ignacio I., Stevenson, Christopher S., Spira, Avrum E., Wang, Linghua, Kadara, Humam
Publicado 2021